← Cofactor catalogue
Prosthetic group
cobalamin
CofactorMech:cobalamin · CHEBI:30411
cobalamin is represented by the precise ChEBI entity CHEBI:30411. Cofactor roles are chemical-context annotations; ingredient links describe chemical supply and do not establish uptake, bioavailability or a requirement for every organism. This class leaves the cobalt oxidation state unspecified and is not substituted for methylcobalamin or adenosylcobalamin.
Download source YAML · View source at this revision
Chemical identity evidence
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ChEBI CHEBI:30411 — ChEBI assigns a cofactor, coenzyme or prosthetic-group role to CHEBI:30411.
Source reference · JSON Pointer /roles_classification · Source licence: CC-BY-4.0
Scoped relationships
Provisional links retain upstream ingredient identifiers. Verified links describe the cited source context, not universal organism requirements. Conjugate forms and precursor supply are distinct relationships.
Supplied by · CHEBI:30411
PROVISIONAL · mediaingredientmech
The current MIM ontology mapping exactly matches the candidate cofactor chemical identifier. This establishes a compound supply link, not organism-specific uptake or requirement.
Linked source record: data/ingredients/mapped/Cobalamine.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142
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MIM ingredient identity — The cited ingredient is mapped to CHEBI:30411; this is a compound-identity assertion, not a bioavailability measurement.
Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0
Required by · proteintraitsmech:COFACTOR_REQ_CHEBI_30411
VERIFIED · proteintraitsmech
Conceptual requirement coverage: this PTM trait defines the requirement for the same ChEBI chemical. It is not an organism-level or enzyme-level measurement.
Linked source record: data/traits/function/cofactor_requirement/chebi/cobalamin-chebi30411.yaml
Source revision: 8d08b33cfbee1e9d1c2fdb2211b82b49dd0c8b1f
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PTM cofactor-requirement concept — The target is a CLASS trait with an explicit cross-reference to this chemical, rather than a measured protein observation.
Source reference · JSON Pointer /xrefs · Source licence: CC-BY-4.0
Research gaps
- pathwaymech: No exact-identifier cofactor-use or production link verified in the complete 282-record PathwayMech snapshot. Related broader/narrower chemical forms are not substituted. Specific methyl/adenosyl forms cannot establish this unspecified-oxidation-state class as the exact endpoint.
- proteintraitsmech: The curated PTM link covers a cofactor-requirement concept only. A separately sourced, named enzyme exemplar requiring this exact chemical has not been curated in this seed record.