← Cofactor catalogue
Coenzyme
coenzyme A
CofactorMech:coenzyme-a · CHEBI:15346
coenzyme A is represented by the precise ChEBI entity CHEBI:15346. Cofactor roles are chemical-context annotations; ingredient links describe chemical supply and do not establish uptake, bioavailability or a requirement for every organism.
Download source YAML · View source at this revision
Chemical identity evidence
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ChEBI CHEBI:15346 — ChEBI assigns a cofactor, coenzyme or prosthetic-group role to CHEBI:15346.
Source reference · JSON Pointer /roles_classification · Source licence: CC-BY-4.0
Scoped relationships
Provisional links retain upstream ingredient identifiers. Verified links describe the cited source context, not universal organism requirements. Conjugate forms and precursor supply are distinct relationships.
Supplied by · CHEBI:15346
PROVISIONAL · mediaingredientmech
The current MIM ontology mapping exactly matches the candidate cofactor chemical identifier. This establishes a compound supply link, not organism-specific uptake or requirement.
Linked source record: data/ingredients/mapped/Coenzyme_A.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142
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MIM ingredient identity — The cited ingredient is mapped to CHEBI:15346; this is a compound-identity assertion, not a bioavailability measurement.
Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0
Required by · proteintraitsmech:COFACTOR_REQ_CHEBI_15346
VERIFIED · proteintraitsmech
Conceptual requirement coverage: this PTM trait defines the requirement for the same ChEBI chemical. It is not an organism-level or enzyme-level measurement.
Linked source record: data/traits/function/cofactor_requirement/chebi/coenzyme-a-chebi15346.yaml
Source revision: 8d08b33cfbee1e9d1c2fdb2211b82b49dd0c8b1f
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PTM cofactor-requirement concept — The target is a CLASS trait with an explicit cross-reference to this chemical, rather than a measured protein observation.
Source reference · JSON Pointer /xrefs · Source licence: CC-BY-4.0
Conjugate form produced by · MetaCyc:COA-PWY
VERIFIED · pathwaymech
PathwayMech edge edge-021 records RHEA:18246 produces CHEBI:57287. This is a cross-reference to the source-scoped reaction or cofactor annotation, not proof of complete pathway flux. The pathway chemical is CHEBI:57287, a distinct conjugate form of CHEBI:15346; this link does not identify their charge states.
Target chemical: CHEBI:57287
Linked source record: data/pathways/coenzyme-a-biosynthesis-i-prokaryotic.yaml
Source revision: 9584009d49579267233124f4a1057b9425a007d9
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PathwayMech reaction or cofactor edge — PathwayMech edge edge-021 records RHEA:18246 produces CHEBI:57287. This is a cross-reference to the source-scoped reaction or cofactor annotation, not proof of complete pathway flux.
Source reference · JSON Pointer /mechanistic_edges/20 · Source licence: CC-BY-4.0
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ChEBI CHEBI:15346 — ChEBI provides the conjugate-form relationship linking the source chemical family to CHEBI:57287.
Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0
Research gaps
- proteintraitsmech: The curated PTM link covers a cofactor-requirement concept only. A separately sourced, named enzyme exemplar requiring this exact chemical has not been curated in this seed record.