← Cofactor catalogue
Metal ion
copper(2+)
CofactorMech:copper · CHEBI:29036
copper(2+) is represented by the precise ChEBI entity CHEBI:29036. Cofactor roles are chemical-context annotations; ingredient links describe chemical supply and do not establish uptake, bioavailability or a requirement for every organism.
Download source YAML · View source at this revision
Chemical identity evidence
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ChEBI CHEBI:29036 — ChEBI assigns a cofactor, coenzyme or prosthetic-group role to CHEBI:29036.
Source reference · JSON Pointer /roles_classification · Source licence: CC-BY-4.0
Scoped relationships
Provisional links retain upstream ingredient identifiers. Verified links describe the cited source context, not universal organism requirements. Conjugate forms and precursor supply are distinct relationships.
Supplied by · CHEBI:49553
PROVISIONAL · mediaingredientmech
The source is a chemically specified salt containing this metal in the +2 oxidation state; supply is chemical composition, not proof of uptake, cellular availability or enzyme occupancy.
Linked source record: data/ingredients/mapped/Cucl2.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142
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MIM ingredient identity — The cited ingredient is mapped to CHEBI:49553; this is a compound-identity assertion, not a bioavailability measurement.
Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0
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ChEBI CHEBI:49553 — The source compound contains the metal in oxidation state +2, corresponding to CHEBI:29036; supply does not imply enzyme occupancy.
Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0
Supplied by · CHEBI:86318
PROVISIONAL · mediaingredientmech
The source is a chemically specified salt containing this metal in the +2 oxidation state; supply is chemical composition, not proof of uptake, cellular availability or enzyme occupancy.
Linked source record: data/ingredients/mapped/Cucl2_X_2_H2o.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142
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MIM ingredient identity — The cited ingredient is mapped to CHEBI:86318; this is a compound-identity assertion, not a bioavailability measurement.
Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0
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ChEBI CHEBI:86318 — The exact source salt or hydrate supplies the chemical component represented by CHEBI:49553; this is a composition relationship.
Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0
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ChEBI CHEBI:49553 — The parent salt contains the metal in oxidation state +2; the resulting ion is CHEBI:29036.
Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0
Supplied by · CHEBI:91245
PROVISIONAL · mediaingredientmech
The source is a chemically specified salt containing this metal in the +2 oxidation state; supply is chemical composition, not proof of uptake, cellular availability or enzyme occupancy.
Linked source record: data/ingredients/mapped/Cucl2_X_5_H2o.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142
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MIM ingredient identity — The cited ingredient is mapped to CHEBI:91245; this is a compound-identity assertion, not a bioavailability measurement.
Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0
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ChEBI CHEBI:91245 — The exact source salt or hydrate supplies the chemical component represented by CHEBI:49553; this is a composition relationship.
Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0
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ChEBI CHEBI:49553 — The parent salt contains the metal in oxidation state +2; the resulting ion is CHEBI:29036.
Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0
Required by · proteintraitsmech:COFACTOR_REQ_CHEBI_29036
VERIFIED · proteintraitsmech
Conceptual requirement coverage: this PTM trait defines the requirement for the same ChEBI chemical. It is not an organism-level or enzyme-level measurement.
Linked source record: data/traits/function/cofactor_requirement/chebi/copper-2-chebi29036.yaml
Source revision: 8d08b33cfbee1e9d1c2fdb2211b82b49dd0c8b1f
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PTM cofactor-requirement concept — The target is a CLASS trait with an explicit cross-reference to this chemical, rather than a measured protein observation.
Source reference · JSON Pointer /xrefs · Source licence: CC-BY-4.0
Research gaps
- pathwaymech: No exact-identifier cofactor-use or production link verified in the complete 282-record PathwayMech snapshot. Related broader/narrower chemical forms are not substituted. Exact Cu(2+) occurrences were inhibition or activation observations; the SOD1 cofactor is the broader copper-cation entity CHEBI:23378.
- proteintraitsmech: The curated PTM link covers a cofactor-requirement concept only. A separately sourced, named enzyme exemplar requiring this exact chemical has not been curated in this seed record.