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Metal ion

manganese(2+)

CofactorMech:manganese · CHEBI:29035

manganese(2+) is represented by the precise ChEBI entity CHEBI:29035. Cofactor roles are chemical-context annotations; ingredient links describe chemical supply and do not establish uptake, bioavailability or a requirement for every organism.

Download source YAML · View source at this revision

Chemical identity evidence

Scoped relationships

Provisional links retain upstream ingredient identifiers. Verified links describe the cited source context, not universal organism requirements. Conjugate forms and precursor supply are distinct relationships.

Supplied by · CHEBI:86360

PROVISIONAL · mediaingredientmech

The source is a chemically specified salt containing this metal in the +2 oxidation state; supply is chemical composition, not proof of uptake, cellular availability or enzyme occupancy.

Linked source record: data/ingredients/mapped/Mnso4.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142

  • MIM ingredient identity — The cited ingredient is mapped to CHEBI:86360; this is a compound-identity assertion, not a bioavailability measurement.

    Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86360 — The source compound contains the metal in oxidation state +2, corresponding to CHEBI:29035; supply does not imply enzyme occupancy.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

Supplied by · CHEBI:86364

PROVISIONAL · mediaingredientmech

The source is a chemically specified salt containing this metal in the +2 oxidation state; supply is chemical composition, not proof of uptake, cellular availability or enzyme occupancy.

Linked source record: data/ingredients/mapped/Mnso4_X_1_H2o.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142

  • MIM ingredient identity — The cited ingredient is mapped to CHEBI:86364; this is a compound-identity assertion, not a bioavailability measurement.

    Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86364 — The exact source salt or hydrate supplies the chemical component represented by CHEBI:86360; this is a composition relationship.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86360 — The parent salt contains the metal in oxidation state +2; the resulting ion is CHEBI:29035.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

Supplied by · CHEBI:86356

PROVISIONAL · mediaingredientmech

The source is a chemically specified salt containing this metal in the +2 oxidation state; supply is chemical composition, not proof of uptake, cellular availability or enzyme occupancy.

Linked source record: data/ingredients/mapped/Mnso4_X_2_H2o.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142

  • MIM ingredient identity — The cited ingredient is mapped to CHEBI:86356; this is a compound-identity assertion, not a bioavailability measurement.

    Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86356 — The exact source salt or hydrate supplies the chemical component represented by CHEBI:86360; this is a composition relationship.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86360 — The parent salt contains the metal in oxidation state +2; the resulting ion is CHEBI:29035.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

Supplied by · CHEBI:86358

PROVISIONAL · mediaingredientmech

The source is a chemically specified salt containing this metal in the +2 oxidation state; supply is chemical composition, not proof of uptake, cellular availability or enzyme occupancy.

Linked source record: data/ingredients/mapped/Mnso4_X_4_H2o.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142

  • MIM ingredient identity — The cited ingredient is mapped to CHEBI:86358; this is a compound-identity assertion, not a bioavailability measurement.

    Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86358 — The exact source salt or hydrate supplies the chemical component represented by CHEBI:86360; this is a composition relationship.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86360 — The parent salt contains the metal in oxidation state +2; the resulting ion is CHEBI:29035.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

Supplied by · CHEBI:131524

PROVISIONAL · mediaingredientmech

The source is a chemically specified salt containing this metal in the +2 oxidation state; supply is chemical composition, not proof of uptake, cellular availability or enzyme occupancy.

Linked source record: data/ingredients/mapped/Mnso4_X_5_H2o.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142

  • MIM ingredient identity — The cited ingredient is mapped to CHEBI:131524; this is a compound-identity assertion, not a bioavailability measurement.

    Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0

  • ChEBI CHEBI:131524 — The exact source salt or hydrate supplies the chemical component represented by CHEBI:86360; this is a composition relationship.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86360 — The parent salt contains the metal in oxidation state +2; the resulting ion is CHEBI:29035.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

Supplied by · CHEBI:131523

PROVISIONAL · mediaingredientmech

The source is a chemically specified salt containing this metal in the +2 oxidation state; supply is chemical composition, not proof of uptake, cellular availability or enzyme occupancy.

Linked source record: data/ingredients/mapped/Mnso4_X_6_H2o.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142

  • MIM ingredient identity — The cited ingredient is mapped to CHEBI:131523; this is a compound-identity assertion, not a bioavailability measurement.

    Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0

  • ChEBI CHEBI:131523 — The exact source salt or hydrate supplies the chemical component represented by CHEBI:86360; this is a composition relationship.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86360 — The parent salt contains the metal in oxidation state +2; the resulting ion is CHEBI:29035.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

Supplied by · CHEBI:86364

PROVISIONAL · mediaingredientmech

The source is a chemically specified salt containing this metal in the +2 oxidation state; supply is chemical composition, not proof of uptake, cellular availability or enzyme occupancy.

Linked source record: data/ingredients/mapped/Mnso4_X_H2o.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142

  • MIM ingredient identity — The cited ingredient is mapped to CHEBI:86364; this is a compound-identity assertion, not a bioavailability measurement.

    Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86364 — The exact source salt or hydrate supplies the chemical component represented by CHEBI:86360; this is a composition relationship.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

  • ChEBI CHEBI:86360 — The parent salt contains the metal in oxidation state +2; the resulting ion is CHEBI:29035.

    Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0

Required by · proteintraitsmech:COFACTOR_REQ_CHEBI_29035

VERIFIED · proteintraitsmech

Conceptual requirement coverage: this PTM trait defines the requirement for the same ChEBI chemical. It is not an organism-level or enzyme-level measurement.

Linked source record: data/traits/function/cofactor_requirement/chebi/manganese-2-chebi29035.yaml
Source revision: 8d08b33cfbee1e9d1c2fdb2211b82b49dd0c8b1f

  • PTM cofactor-requirement concept — The target is a CLASS trait with an explicit cross-reference to this chemical, rather than a measured protein observation.

    Source reference · JSON Pointer /xrefs · Source licence: CC-BY-4.0

Used by · gomodel:YeastPathways_DETOX1-PWY

VERIFIED · pathwaymech

PathwayMech edge cofactor-b8aa1e3a2c24 records SGD:S000001050 has_cofactor CHEBI:29035. This is a cross-reference to the source-scoped reaction or cofactor annotation, not proof of complete pathway flux. SOD2 cofactor support is a reviewed UniProt annotation by similarity; it is not a newly checked direct yeast metal assay.

Linked source record: data/pathways/superoxide-radicals-degradation.yaml
Source revision: 9584009d49579267233124f4a1057b9425a007d9

  • PathwayMech reaction or cofactor edge — PathwayMech edge cofactor-b8aa1e3a2c24 records SGD:S000001050 has_cofactor CHEBI:29035. This is a cross-reference to the source-scoped reaction or cofactor annotation, not proof of complete pathway flux. SOD2 cofactor support is a reviewed UniProt annotation by similarity; it is not a newly checked direct yeast metal assay.

    Source reference · JSON Pointer /mechanistic_edges/33 · Source licence: CC-BY-4.0

Research gaps

Curation provenance

Recorded curation events
UTC timestampAction and curatorSummary
CREATE · cofactor-stream-cCurate initial source-backed cofactor and scoped cross-corpus links
History source