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Coenzyme
pyridoxal 5'-phosphate
CofactorMech:pyridoxal-phosphate · CHEBI:18405
pyridoxal 5'-phosphate is represented by the precise ChEBI entity CHEBI:18405. Cofactor roles are chemical-context annotations; ingredient links describe chemical supply and do not establish uptake, bioavailability or a requirement for every organism.
Download source YAML · View source at this revision
Chemical identity evidence
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ChEBI CHEBI:18405 — ChEBI assigns a cofactor, coenzyme or prosthetic-group role to CHEBI:18405.
Source reference · JSON Pointer /roles_classification · Source licence: CC-BY-4.0
Scoped relationships
Provisional links retain upstream ingredient identifiers. Verified links describe the cited source context, not universal organism requirements. Conjugate forms and precursor supply are distinct relationships.
Supplied by · CHEBI:18405
PROVISIONAL · mediaingredientmech
The current MIM ontology mapping exactly matches the candidate cofactor chemical identifier. This establishes a compound supply link, not organism-specific uptake or requirement.
Linked source record: data/ingredients/mapped/Pyridoxal_Phosphate.yaml
Source revision: 0529fc6bc065bfa04aba0aed234f6b0cfad6a142
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MIM ingredient identity — The cited ingredient is mapped to CHEBI:18405; this is a compound-identity assertion, not a bioavailability measurement.
Source reference · JSON Pointer /identifier · Source licence: CC-BY-4.0
Required by · proteintraitsmech:COFACTOR_REQ_CHEBI_18405
VERIFIED · proteintraitsmech
Conceptual requirement coverage: this PTM trait defines the requirement for the same ChEBI chemical. It is not an organism-level or enzyme-level measurement.
Linked source record: data/traits/function/cofactor_requirement/chebi/pyridoxal-5-phosphate-chebi18405.yaml
Source revision: 8d08b33cfbee1e9d1c2fdb2211b82b49dd0c8b1f
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PTM cofactor-requirement concept — The target is a CLASS trait with an explicit cross-reference to this chemical, rather than a measured protein observation.
Source reference · JSON Pointer /xrefs · Source licence: CC-BY-4.0
Conjugate form produced by · MetaCyc:PYRIDOXSYN-PWY
VERIFIED · pathwaymech
PathwayMech edge edge-035 records RHEA:15150 produces CHEBI:597326. This is a cross-reference to the source-scoped reaction or cofactor annotation, not proof of complete pathway flux. The pathway chemical is CHEBI:597326, a distinct conjugate form of CHEBI:18405; this link does not identify their charge states.
Target chemical: CHEBI:597326
Linked source record: data/pathways/pyridoxal-5-phosphate-biosynthesis-i.yaml
Source revision: 9584009d49579267233124f4a1057b9425a007d9
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PathwayMech reaction or cofactor edge — PathwayMech edge edge-035 records RHEA:15150 produces CHEBI:597326. This is a cross-reference to the source-scoped reaction or cofactor annotation, not proof of complete pathway flux.
Source reference · JSON Pointer /mechanistic_edges/34 · Source licence: CC-BY-4.0
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ChEBI CHEBI:18405 — ChEBI provides the conjugate-form relationship linking the source chemical family to CHEBI:597326.
Source reference · JSON Pointer /ontology_relations · Source licence: CC-BY-4.0
Research gaps
- proteintraitsmech: The curated PTM link covers a cofactor-requirement concept only. A separately sourced, named enzyme exemplar requiring this exact chemical has not been curated in this seed record.