Early Dental Biofilm Five-Species Model

Community ID CommunityMech:000081

Ecological State ENGINEERED

Environment dental plaque biofilm on tooth surface
ENVO:01001034

A defined five-member oral biofilm model representing early acidogenic stages of the caries process. The community combines Streptococcus oralis, Streptococcus sanguinis, Streptococcus mitis, Streptococcus downei, and Actinomyces naeslundii in flow-channel biofilms to reproduce the composition, architecture, and microscale pH heterogeneity of early dental plaque.

Taxonomy

Taxon	Ontology ID	Abundance
Streptococcus oralis	NCBITaxon:1303	N/A
PMID:21966490 - SUPPORT (IN_VITRO) "Strains of Streptococcus oralis, Streptococcus sanguinis, Streptococcus mitis, Streptococcus downei and Actinomyces naeslundii were employed in the model."
Streptococcus sanguinis	NCBITaxon:1305	N/A
PMID:21966490 - SUPPORT (IN_VITRO) "Strains of Streptococcus oralis, Streptococcus sanguinis, Streptococcus mitis, Streptococcus downei and Actinomyces naeslundii were employed in the model."
Streptococcus mitis	NCBITaxon:28037	N/A
PMID:21966490 - SUPPORT (IN_VITRO) "Strains of Streptococcus oralis, Streptococcus sanguinis, Streptococcus mitis, Streptococcus downei and Actinomyces naeslundii were employed in the model."
Streptococcus downei	NCBITaxon:1317	N/A
PMID:21966490 - SUPPORT (IN_VITRO) "Strains of Streptococcus oralis, Streptococcus sanguinis, Streptococcus mitis, Streptococcus downei and Actinomyces naeslundii were employed in the model."
Actinomyces naeslundii	NCBITaxon:1655	N/A
PMID:21966490 - SUPPORT (IN_VITRO) "Strains of Streptococcus oralis, Streptococcus sanguinis, Streptococcus mitis, Streptococcus downei and Actinomyces naeslundii were employed in the model."

Ecological Interactions

ℹ️ No detailed ecological interaction data is available for this community.

This record may be a metabolic model or minimal entry containing only taxonomy and external resource links.

Environmental Factors

Factor	Value	Unit
Glucose challenge		N/A
PMID:21966490 - SUPPORT (IN_VITRO) "We employed the pH-sensitive ratiometric probe C-SNARF-4 to perform real-time microscopic analyses of the biofilm pH in response to salivary solutions containing glucose."
Persistent acidic microenvironments		N/A
PMID:21966490 - SUPPORT (IN_VITRO) "Anaerobic glycolysis in the model biofilms created a mildly acidic environment. Decrease in pH in different areas of the biofilms varied, and distinct extracellular pH-microenvironments were conserved over several hours."