{"cross_mech":[],"family":{"alphafold_models":29396,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family of proteins are related to a large superfamily of metalloenzymes [[cite:PUB00004994]]. TatD, a member of this family has been shown experimentally to be a DNase enzyme.","domain_architectures":259,"interpro_id":"IPR001130","known_evidence_count":null,"matches":42379,"name":"TatD related DNase","partial_evidence_count":null,"pfam_id":"PF01026","proteins":42146,"proteomes":21954,"short_name":"TatD_DNase","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01026","structures":16,"taxa":35333,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF01026.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":29396,"domain_architectures":259,"matches":42379,"proteins":42146,"proteomes":21954,"structures":16,"taxa":35333},"curation_status":"SEEDED","description":"This family of proteins are related to a large superfamily of metalloenzymes [[cite:PUB00004994]]. TatD, a member of this family has been shown experimentally to be a DNase enzyme.","id":"Pfam:PF01026","interpro_id":"InterPro:IPR001130","name":"TatD related DNase","pfam_id":"PF01026","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"TatD_DNase","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01026"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF01026.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"4a8df2b303c41bfe3ee6cf60cea7abe7284975af1c8711d3c8c71e3f4b11c89c"}},"protein_examples":{"candidate_count":18,"discovery_scanned":true,"example_count":18,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Erwinia billingiae (strain Eb661)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-2.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01090","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-2.yaml"}],"pfam_ids":["PF01026"],"protein_name":"3'-5' ssDNA/RNA exonuclease TatD","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MFDIGVNLTSTQFAKDRDQVVKRAKDAGITGLLITGTNALESQQAQSLATRRPGYCWSTAGVHPHHASEWSGETAATLKRLAESPEVVAIGECGLDFNRNISEPEQQVYAFNAQLELAAELAMPVFLHCRDAHDRFLAVLTPWLPTLPGAVVHCFTGTREELEACLAAGLSIGITGWVCDERRGVELRELMPLIPADRLLLETDAPYLLPRDMRPRPPSRRNEPCFLPHIVQVVAGLRGEEPEALGRQCDANARKLFRLPA","sequence_length":261,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"0635bd784bf56419506a95d809b8b584925c478c71711a6ac025e03826446837","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/D8MKW4.json","taxon_id":"634500","uniprot_accession":"D8MKW4","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-1.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01137","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-1.yaml"}],"pfam_ids":["PF01026"],"protein_name":"Uncharacterized metal-dependent hydrolase TatD","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MVDAHTHLDACGARDADTVRSLVERAAAAGVTAVVTVADDLESARWVTRAAEWDRRVYAAVALHPTRADALTDAARAELERLVAHPRVVAVGETGIDMYWPGRLDGCAEPHVQREAFAWHIDLAKRTGKPLMIHNRQADRDVLDVLRAEGAPDTVILHCFSSDAAMARTCVDAGWLLSLSGTVSFRTARELREAVPLMPVEQLLVETDAPYLTPHPHRGLANEPYCLPYTVRALAELVNRRPEEVALITTSNARRAYGLGWMRQ","sequence_length":264,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"c32a215b21710b452d4ccf1d0f48601f30a5a892aa486bb4ac959d4c0ad23fb6","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/O08343.json","taxon_id":"83332","uniprot_accession":"O08343","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/metal-dependent-hydrolase-nf008075.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:NF008075","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/metal-dependent-hydrolase-nf008075.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/ychf-tatd-family-dna-exonuclease-tigr00010.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:TIGR00010","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/ychf-tatd-family-dna-exonuclease-tigr00010.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-1.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01137","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-1.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-3.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01091","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-3.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P0AFQ7","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF01026"],"protein_name":"Uncharacterized metal-dependent hydrolase YcfH","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"ac89426d47e4467a60825e444742d8941ea2c55d526ea444c36644f74e81bc1f","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTLPGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYTPETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTEDRETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKENQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR","sequence_length":265,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"ac89426d47e4467a60825e444742d8941ea2c55d526ea444c36644f74e81bc1f","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P0AFQ7.json","taxon_id":"83333","uniprot_accession":"P0AFQ7","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/enzymatic_activity/ec/3-1-11-ec3-1-11--.yaml","qualification_status":"NOT_ASSESSED","record_id":"EC:3.1.11.-","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/enzymatic_activity/ec/3-1-11-ec3-1-11--.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/dna-nuclease-activity-go0004536.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0004536","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/dna-nuclease-activity-go0004536.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/3-5-ssdna-rna-exonuclease-tatd-nf007745.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:NF007745","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/3-5-ssdna-rna-exonuclease-tatd-nf007745.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018228","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd01310","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-2.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01090","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-2.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-3.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01091","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-3.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P27859","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF01026"],"protein_name":"3'-5' ssDNA/RNA exonuclease TatD","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"e2c60f5c996cf594f50be0fea16fba662ffc4e1fde99f3f69c98c7097abfb83e","sequence_version":3,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_02","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MFDIGVNLTSSQFAKDRDDVVACAFDAGVNGLLITGTNLRESQQAQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNFSTPEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREEMQACVAHGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSSRRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF","sequence_length":260,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"e2c60f5c996cf594f50be0fea16fba662ffc4e1fde99f3f69c98c7097abfb83e","sequence_version":3,"source_url":"https://rest.uniprot.org/uniprotkb/P27859.json","taxon_id":"83333","uniprot_accession":"P27859","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-2.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01090","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-2.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-3.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01091","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-3.yaml"}],"pfam_ids":["PF01026"],"protein_name":"Deoxyribonuclease Tat-D","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MWGILLKSSNKSCSRLWKPILTQYYSMTSTATDSPLKYYDIGLNLTDPMFHGIYNGKQYHPADYVKLLERAAQRHVKNALVTGSSIAESQSAIELVSSVKDLSPLKLYHTIGVHPCCVNEFADASQGDKASASIDNPSMDEAYNESLYAKVISNPSFAQGKLKELYDLMNQQAKPHDTSFRSIGEIGLDYDRFHYSSKEMQKVFFEEQLKISCLNDKLSSYPLFLHMRSACDDFVQILERFIAGFTDERDTFQLQKLGASSSSGFYKFHPDRKLVVHSFTGSAIDLQKLLNLSPNIFIGVNGCSLRTEENLAVVKQIPTERLLLETDAPWCEIKRTHASFQYLAKYQEVRDFEYPAFKSVKKNKLADKLNAEELYMVKGRNEPCNMEQVAIVVSEVKDVDLATLIDTTWKTTCKIFGE","sequence_length":418,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"4af249634857ce02af4e1ec6f165bd9ab1e29c94750a26ba7c0b2b33377116c8","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P34220.json","taxon_id":"559292","uniprot_accession":"P34220","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacillus subtilis (strain 168)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/ychf-tatd-family-dna-exonuclease-tigr00010.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:TIGR00010","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/ychf-tatd-family-dna-exonuclease-tigr00010.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018228","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd01310","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P37545","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF01026"],"protein_name":"Uncharacterized metal-dependent hydrolase YabD","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"d4ca3d61521dabe4898e5f6fc49cb1d0edb279b41311a8a17bf6fe482ec9c109","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MLFDTHAHLNAEQYDTDLEEVIERAKAEKVERIVVVGFDRPTITRAMEMIEEYDFIYAAIGWHPVDAIDMTEEDLAWIKELSAHEKVVAIGEMGLDYHWDKSPKDIQKEVFRNQIALAKEVNLPIIIHNRDATEDVVTILKEEGAEAVGGIMHCFTGSAEVARECMKMNFYLSFGGPVTFKNAKKPKEVVKEIPNDRLLIETDCPFLTPHPFRGKRNEPSYVKYVAEQIAELKEMTFEEIASITTENAKRLFRIN","sequence_length":255,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"d4ca3d61521dabe4898e5f6fc49cb1d0edb279b41311a8a17bf6fe482ec9c109","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P37545.json","taxon_id":"224308","uniprot_accession":"P37545","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018228","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml"}],"pfam_ids":["PF01026"],"protein_name":"Uncharacterized deoxyribonuclease YMR262W","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MNKLVDAHCHVITDPDNTFCGDDGGSQGTLRCVMSSNPYDWNNLKKLAGRSTSKNDICVGFGVHPWYSHLFYVGSRRDKVSHYQDVLEYKNEEQFDSLVQVLPEPLDLEEYIKREFNDTLVSVIGEIGLDKLFRLPANGFYMQNEKARLTTVKVKLSHQETVFRRFCRLARHTSKPISIHDVKCHGKLNDICNEELLTYHSVKICLHSYTGSKETLLGQWLKKFPPDRIFVSLSKWINFKDPEEGDALVRSLPSTCILTETDYPIDNPDPSYQKALTEQLQYLNAQIARAWDETLDASQAALRVYENFQKFIK","sequence_length":313,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"28552f2147c8f29506c4714ebd22cc57559c7c9b1bd39e07c26eacb315aa4499","sequence_version":3,"source_url":"https://rest.uniprot.org/uniprotkb/P38430.json","taxon_id":"559292","uniprot_accession":"P38430","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/metal-dependent-hydrolase-nf008522.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:NF008522","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/metal-dependent-hydrolase-nf008522.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-1.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01137","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-1.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-2.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01090","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-2.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P39408","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF01026"],"protein_name":"Uncharacterized metal-dependent hydrolase YjjV","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"5008a1682e365dac6e88095a0653e343e632c558df06d257744ab7d537844d64","sequence_version":2,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MICRFIDTHCHFDFPPFSGDEEASLQRAAQAGVGKIIVPATEAENFARVLALAENYQPLYAALGLHPGMLEKHSDVSLEQLQQALERRPAKVVAVGEIGLDLFGDDPQFERQQWLLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRHDLPRTGVVHGFSGSLQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASLLLETDAPDMPLNGFQGQPNRPEQAARVFAVLCELRREPADEIAQALLNNTYTLFNVP","sequence_length":259,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"5008a1682e365dac6e88095a0653e343e632c558df06d257744ab7d537844d64","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/P39408.json","taxon_id":"83333","uniprot_accession":"P39408","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-1.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01137","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-1.yaml"}],"pfam_ids":["PF01026"],"protein_name":"D-aminoacyl-tRNA deacylase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MHLVDTHVHINFDVFAADLDQLQHRWRQAGVVQLVHSCVKPQEFDQIQSLADRFPELFFAVGLHPLDAEDWQDNTAGQILAYAKADDRVVAIGEMGLDFFKADNRDHQIEVFRAQLAIARELNKPVIIHCRDAAQTMRQVLTDFQAESGPVAGVMHCWGGTPEETQWFLDLGFYISFSGTVTFKKAEGIQASAQMVPPDRLLVETDCPFLAPVPQRGKRNEPAFVRHVAEAIAALRHVPLETLAQQTTTNARNLFKLPVPA","sequence_length":261,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"ca6a11ada29e9650a3b9645844fb56003a209d5d2a4fbcf8aaa52490e2d2637d","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P73335.json","taxon_id":"1111708","uniprot_accession":"P73335","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd01310","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml"}],"pfam_ids":["PF01026"],"protein_name":"Deoxyribonuclease TATDN3","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MRAAGVGLVDCHCHLSAPDFDRDLDDVLEKAKKANVVALVAVAEHSGEFEKIMQLSERYNGFVLPCLGVHPVQGLPPEDQRSVTLKDLDVALPIIENYKDRLLAIGEVGLDFSPRFAGTGEQKEEQRQVLIRQIQLAKRLNLPVNVHSRSAGRPTINLLQEQGAEKVLLHAFDGRPSVAMEGVRAGYFFSIPPSIIRSGQKQKLVKQLPLTSICLETDSPALGPEKQVRNEPWNISISAEYIAQVKGISVEEVIEVTTQNALKLFPKLRHLLQK","sequence_length":274,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"a06217b79fdad377c38ce6ad2365ceae020456d33c6c7f44aa3cb38a67634b08","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q17R31.json","taxon_id":"9606","uniprot_accession":"Q17R31","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd01310","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml"}],"pfam_ids":["PF01026"],"protein_name":"Putative deoxyribonuclease TATDN3","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGLGLVDCHCHLSASDFDNDLDDVLEKARKANVMALVAVAEHAGEFERIMQLSERYNGFVLPCLGVHPVQELSPEKPRSVTLKDLDVALPIIEKYKDRLLAIGEVGLDFTPRYAGTDEEKEEQRQVLIRQVQLAKRLNVPLNVHSRSAGRPTISLLREQGAEQVLLHAFDGRPSVAMEGVRAGYYFSIPPSIVRSGQKQKLVKQLPLSSICLETDSPALGPEKLTRNEPCNISIAAEFIAQVKGISVEEVREVTTRNAFRLFPKLQSLLQKELQSHPLQAKSAQGSAGESKGLL","sequence_length":294,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"509c350e53beeb930c91e59351406e0edabf25002e79620d18815fbcb9d2dd13","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q3U1C6.json","taxon_id":"10090","uniprot_accession":"Q3U1C6","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018228","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:Q58171","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF01026"],"protein_name":"Uncharacterized metal-dependent hydrolase MJ0761","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"56d45ed11b921048667207a2ac61052821c68b675f73611c127a197054b5dc98","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MIDAHTHLDVRSFEDLEKMALSGIETIITCAHDPYKMSTPEVYLDHWDRLINLEVKRGEMAGVEVKVAVGVHPMGYPKNWEVLIKKLPEFLDNENVVAIGETGLHYLTEDEKNLLREQLYLAKDYNMPIIIHTPEKNKKEALIEILKILDEVKIKDSLVMIDHINKETVDLIDRDVYVGLTVQPSMKLTHEEAAEIIKNYNKKFILSSDLGSLKADIYALPRTKLYMKNIGVDEEKIIASVYKNAKGFYRL","sequence_length":251,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"56d45ed11b921048667207a2ac61052821c68b675f73611c127a197054b5dc98","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q58171.json","taxon_id":"243232","uniprot_accession":"Q58171","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml"}],"pfam_ids":["PF01026"],"protein_name":"Uncharacterized protein MJ1127","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MDVLKSLPVTDNHIHVDDKHGYGAEKVAKTFYNAGGKVMIVLNKPTFDGNLTASMDILVRDVEIINKNTPVKAFGLVGVHPAELTYLMKFMSLEEAKQRIVDALNYAKKLVEEYDFIVGIGEVGRPHYPVSEDVWKASNEILKYCMELAKDIGCAIQIHAESSTEEQFKEFSEMAKEVGLNPEKVVKHHCGNMVLEGERYGIFPSILASRVNEDVVKKSLRFVMETDYIDDLKRPGVALGIKTVPRVTRRLIEKGVLDEEGVYKIHKENIERIYDMDLEL","sequence_length":280,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"481c0696b05cd4579839c66b70ecccf21c46d95c7265fb515abc7d76cb32016c","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q58527.json","taxon_id":"243232","uniprot_accession":"Q58527","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd01310","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml"}],"pfam_ids":["PF01026"],"protein_name":"Uncharacterized protein MJ1383","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MIDTHIHSDTRGLEDLELMAMCLDGVITLAHDPFEMKNIKVWEAHVEKLLINELERAKKVGLNLFICVGMHPRAIPPEIDEALDKIKSYINYNSRVVGIGEIGLEKATKEEKEVFIKQLLLAEELNMPAVVHTPRRNKEEVTKIILDEISTLNLKNRDIVIEHCNKETTKWVLDEEFYVGLTIQPGKLTPLEAVEIVKEYKDFADKILLNSDCSSNASDVLAVPRTVLKMKINGIEKDVIYKVAHKNAVNLFGLDI","sequence_length":256,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"a86222dbb2863151007a73394ef46a7afc22a4672e25eb5c59001056b7ccde47","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q58778.json","taxon_id":"243232","uniprot_accession":"Q58778","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/ychf-tatd-family-dna-exonuclease-tigr00010.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:TIGR00010","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/ychf-tatd-family-dna-exonuclease-tigr00010.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018228","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd01310","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:Q58977","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF01026"],"protein_name":"Uncharacterized metal-dependent hydrolase MJ1582","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"18bba7022e88627430828e8ae0c345dcd32a7810d340db2e8d5e67e7f2579c08","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MRDVKYVDAHCHIEDKAFNKNRDEVIERAKKEDVIIVTSGASLGGCLRALELRKKYNIYLTLGYHPSRVKADDKVIEKVYNLIKNNEYEILAIGEIGMDIKDENYKRQEEIFKKFLSLAEELNKPIVVHARGFERKIFDIAKDKVDIMFHCYSGDVELAKEIGKEGHLISISTLVCFSEHHKKLVESLDLEYLTTETDSPYLSPIKGTKNEPKNVKLVIEEIAKIKEMEVEEVKDVIYKNTCKFFKRRL","sequence_length":249,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"18bba7022e88627430828e8ae0c345dcd32a7810d340db2e8d5e67e7f2579c08","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q58977.json","taxon_id":"243232","uniprot_accession":"Q58977","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018228","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd01310","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/tatd-dnase-pf01026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-3.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01091","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-3.yaml"}],"pfam_ids":["PF01026"],"protein_name":"Deoxyribonuclease TATDN1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSRFKFIDIGINLTDPMFRGIYRGVQKHQDDLQDVIGRAVEIGVKKFMITGGNLQDSKDALHLAQTNGMFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKVVAIGECGLDFDRLQFCPKDTQLKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRTAFPTKKKWESGHCLKDRNEPCHIIQILEIMSAVRDEDPLELANTLYNNTIKVFFPGI","sequence_length":297,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"921f5ba8082a93c9befc0d257aa27d3c5aa22ab22bbe054ccad56c7b6314c289","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q6P1N9.json","taxon_id":"9606","uniprot_accession":"Q6P1N9","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018228","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/conservation/interpro/deoxyribonuclease-tatd-related-conserved-site-ipr018228.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd01310","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/tatd-like-proteins-e-coli-tatd-is-a-cytoplasmic-protein-shown-to-have--cd01310.yaml"}],"pfam_ids":["PF01026"],"protein_name":"Deoxyribonuclease TATDN1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSLFKFVDIGINLTDPMFRGIYRGVQKHQDDLQDVIERAIQIGVKKFMITGGSLQDSKDALQLAQTNDMFFSTVGCHPTRCDEFEKGSPDQYLAGLLSLAENNKGKVVAIGECGLDFDRLQFCPKDTQLKYFEKQFELSEQTQLPMFLHCRNSHTEFLDIMRRNRDRYVGGVVHSFDGTKEAAAALVDLGLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYINTSFPTKKKWENGHCLKDRNEPCHIIQILEIMSAVREEDPLELANTLYNNTIKVFFS","sequence_length":295,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"cc9e8ec8083f58fa3cdc15b68a4e1fd2655420a3abbefc01d474be07d191d83d","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q6P8M1.json","taxon_id":"10090","uniprot_accession":"Q6P8M1","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-1.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01137","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-1.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-2.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01090","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-2.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/pattern/tatd-3.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS01091","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/pattern/tatd-3.yaml"}],"pfam_ids":["PF01026"],"protein_name":"3'-5' RNA nuclease TATDN2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKVDSKDSSHNSTNSEFAAEAEGQNDTIEEPNKVQKRKRDRLRDQGSTMIYLKAIQGILGKSMPKRKGEAATRAKPSAAEHPSHGEGPARSEGPAKTAEGAARSVTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEPLGDRRTVIDKCSPPLEFLDDSDSHLEIQKHKDREVVMEHPSSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYVMYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEEGWSQNSRSFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASSSLPKSHLEPSLEEGFIDTHCHLDMLYSKLSFQGTFTKFRKIYSSSFPKEFQGCISDFCDPRTLTDCLWEELLKEDLVWGAFGCHPHFARYYSESQERNLLQALRHPKAVAFGEMGLDYSYKCTTPVPEQHKVFERQLQLAVSLKKPLVIHCREADEDLLEIMKKFVPPDYKIHRHCFTGSYPVIEPLLKYFPNMSVGFTAVLTYSSAWEAREALRQIPLERIIVETDAPYFLPRQVPKSLCQYAHPGLALHTVREIARVKDQPLSLTLAALRENTSRLYSL","sequence_length":761,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"dfa4ddde8807fa8b843c698f3d52513677907811d1edc9b03669f5107637e813","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q93075.json","taxon_id":"9606","uniprot_accession":"Q93075","uniprot_release":"2026_03"}],"pfam_id":"PF01026","short_name":"TatD_DNase","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}