{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein YbgI","reviewed":true,"short_name":"DUF34_NIF3","source_category":"function/localization/go","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/localization/go/cell-pole-go0060187.yaml","source_record_id":"GO:0060187","source_record_label":"cell pole","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P0AFP6","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein YbgI","reviewed":true,"short_name":"DUF34_NIF3","source_category":"function/protein_family/ncbifam","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","source_record_id":"NCBIfam:TIGR00486","source_record_label":"Nif3-like dinuclear metal center hexameric protein","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P0AFP6","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NGG1-interacting factor 3","reviewed":true,"short_name":"DUF34_NIF3","source_category":"function/protein_family/ncbifam","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","source_record_id":"NCBIfam:TIGR00486","source_record_label":"Nif3-like dinuclear metal center hexameric protein","source_section":"canonical_examples","taxon_id":"NCBITaxon:559292","taxon_label":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","uniprot_accession":"P53081","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein YqfO","reviewed":true,"short_name":"DUF34_NIF3","source_category":"function/protein_family/ncbifam","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","source_record_id":"NCBIfam:TIGR00486","source_record_label":"Nif3-like dinuclear metal center hexameric protein","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"P54472","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein HcgD","reviewed":true,"short_name":"DUF34_NIF3","source_category":"function/protein_family/ncbifam","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","source_record_id":"NCBIfam:TIGR00486","source_record_label":"Nif3-like dinuclear metal center hexameric protein","source_section":"canonical_examples","taxon_id":"NCBITaxon:243232","taxon_label":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","uniprot_accession":"Q58337","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"function/protein_family/ncbifam","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","source_record_id":"NCBIfam:TIGR00486","source_record_label":"Nif3-like dinuclear metal center hexameric protein","source_section":"canonical_examples","taxon_id":"NCBITaxon:10090","taxon_label":"Mus musculus","uniprot_accession":"Q9EQ80","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"function/protein_family/ncbifam","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","source_record_id":"NCBIfam:TIGR00486","source_record_label":"Nif3-like dinuclear metal center hexameric protein","source_section":"canonical_examples","taxon_id":"NCBITaxon:9606","taxon_label":"Homo sapiens","uniprot_accession":"Q9GZT8","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"function/protein_family/ncbifam","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","source_record_id":"NCBIfam:TIGR00486","source_record_label":"Nif3-like dinuclear metal center hexameric protein","source_section":"canonical_examples","taxon_id":"NCBITaxon:7227","taxon_label":"Drosophila melanogaster","uniprot_accession":"Q9NK57","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein YbgI","reviewed":true,"short_name":"DUF34_NIF3","source_category":"function/protein_family/ncbifam","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/protein_family/ncbifam/type-2-gtp-cyclohydrolase-i-nf008064.yaml","source_record_id":"NCBIfam:NF008064","source_record_label":"type 2 GTP cyclohydrolase I","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P0AFP6","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein YbgI","reviewed":true,"short_name":"DUF34_NIF3","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf34-nif3-pf01784.yaml","source_record_id":"Pfam:PF01784","source_record_label":"Duf34/NIF3 (NGG1p interacting factor 3)","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P0AFP6","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf34-nif3-pf01784.yaml","source_record_id":"Pfam:PF01784","source_record_label":"Duf34/NIF3 (NGG1p interacting factor 3)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10090","taxon_label":"Mus musculus","uniprot_accession":"Q9EQ80","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf34-nif3-pf01784.yaml","source_record_id":"Pfam:PF01784","source_record_label":"Duf34/NIF3 (NGG1p interacting factor 3)","source_section":"canonical_examples","taxon_id":"NCBITaxon:9606","taxon_label":"Homo sapiens","uniprot_accession":"Q9GZT8","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF01784","protein_label":"","reviewed":null,"short_name":"DUF34_NIF3","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf34-nif3-pf01784.yaml","source_record_id":"Pfam:PF01784","source_record_label":"Duf34/NIF3 (NGG1p interacting factor 3)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein YbgI","reviewed":true,"short_name":"DUF34_NIF3","source_category":"sequence/homologous_superfamily/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","source_record_id":"InterPro:IPR036069","source_record_label":"DUF34/NIF3 superfamily","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P0AFP6","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NGG1-interacting factor 3","reviewed":true,"short_name":"DUF34_NIF3","source_category":"sequence/homologous_superfamily/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","source_record_id":"InterPro:IPR036069","source_record_label":"DUF34/NIF3 superfamily","source_section":"canonical_examples","taxon_id":"NCBITaxon:559292","taxon_label":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","uniprot_accession":"P53081","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein YqfO","reviewed":true,"short_name":"DUF34_NIF3","source_category":"sequence/homologous_superfamily/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","source_record_id":"InterPro:IPR036069","source_record_label":"DUF34/NIF3 superfamily","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"P54472","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein HcgD","reviewed":true,"short_name":"DUF34_NIF3","source_category":"sequence/homologous_superfamily/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","source_record_id":"InterPro:IPR036069","source_record_label":"DUF34/NIF3 superfamily","source_section":"canonical_examples","taxon_id":"NCBITaxon:243232","taxon_label":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","uniprot_accession":"Q58337","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"sequence/homologous_superfamily/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","source_record_id":"InterPro:IPR036069","source_record_label":"DUF34/NIF3 superfamily","source_section":"canonical_examples","taxon_id":"NCBITaxon:10090","taxon_label":"Mus musculus","uniprot_accession":"Q9EQ80","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"sequence/homologous_superfamily/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","source_record_id":"InterPro:IPR036069","source_record_label":"DUF34/NIF3 superfamily","source_section":"canonical_examples","taxon_id":"NCBITaxon:9606","taxon_label":"Homo sapiens","uniprot_accession":"Q9GZT8","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"sequence/homologous_superfamily/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","source_record_id":"InterPro:IPR036069","source_record_label":"DUF34/NIF3 superfamily","source_section":"canonical_examples","taxon_id":"NCBITaxon:7227","taxon_label":"Drosophila melanogaster","uniprot_accession":"Q9NK57","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein YbgI","reviewed":true,"short_name":"DUF34_NIF3","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","source_record_id":"CATH:3.40.1390.30","source_record_label":"NIF3 (NGG1p interacting factor 3)-like","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P0AFP6","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NGG1-interacting factor 3","reviewed":true,"short_name":"DUF34_NIF3","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","source_record_id":"CATH:3.40.1390.30","source_record_label":"NIF3 (NGG1p interacting factor 3)-like","source_section":"canonical_examples","taxon_id":"NCBITaxon:559292","taxon_label":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","uniprot_accession":"P53081","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein YqfO","reviewed":true,"short_name":"DUF34_NIF3","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","source_record_id":"CATH:3.40.1390.30","source_record_label":"NIF3 (NGG1p interacting factor 3)-like","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"P54472","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like metal-binding protein HcgD","reviewed":true,"short_name":"DUF34_NIF3","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","source_record_id":"CATH:3.40.1390.30","source_record_label":"NIF3 (NGG1p interacting factor 3)-like","source_section":"canonical_examples","taxon_id":"NCBITaxon:243232","taxon_label":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","uniprot_accession":"Q58337","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","source_record_id":"CATH:3.40.1390.30","source_record_label":"NIF3 (NGG1p interacting factor 3)-like","source_section":"canonical_examples","taxon_id":"NCBITaxon:10090","taxon_label":"Mus musculus","uniprot_accession":"Q9EQ80","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","source_record_id":"CATH:3.40.1390.30","source_record_label":"NIF3 (NGG1p interacting factor 3)-like","source_section":"canonical_examples","taxon_id":"NCBITaxon:9606","taxon_label":"Homo sapiens","uniprot_accession":"Q9GZT8","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF01784","protein_label":"NIF3-like protein 1","reviewed":true,"short_name":"DUF34_NIF3","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","source_record_id":"CATH:3.40.1390.30","source_record_label":"NIF3 (NGG1p interacting factor 3)-like","source_section":"canonical_examples","taxon_id":"NCBITaxon:7227","taxon_label":"Drosophila melanogaster","uniprot_accession":"Q9NK57","unknown_status":"KNOWN_HISTORICAL_DUF"}],"family":{"alphafold_models":12676,"candidate_reasons":["name_matches_duf"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":7,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":6},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family includes the DUF34/metal-binding protein/NIF3 proteins, which are widely distributed across superkingdoms. They were previously annotated as GTP cyclohydrolase 1 type 2 [[cite:PUB00070175]] and, recently, through a comprehensive literature review and integrative bioinformatics analyses it was revealed that annotations for these members were misleading as they were based on a single set of in vitro results examining the NIF3 homolog of Helicobacter pylori [[cite:PUB00070175]]. Actually, they have varied phenotypes with the unifying functional role as metal-binding proteins [[cite:PUB00100327]]. This entry contains several NIF3 (NGG1p interacting factor 3) protein homologues. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown [[cite:PUB00002954],[cite:PUB00019927]].","domain_architectures":53,"interpro_id":"IPR002678","known_evidence_count":null,"matches":18654,"name":"Duf34/NIF3 (NGG1p interacting factor 3)","partial_evidence_count":null,"pfam_id":"PF01784","proteins":18574,"proteomes":16807,"short_name":"DUF34_NIF3","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01784","structures":16,"taxa":26806,"unknown_status":"KNOWN_HISTORICAL_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF01784.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":12676,"domain_architectures":53,"matches":18654,"proteins":18574,"proteomes":16807,"structures":16,"taxa":26806},"curation_status":"SEEDED","description":"This family includes the DUF34/metal-binding protein/NIF3 proteins, which are widely distributed across superkingdoms. They were previously annotated as GTP cyclohydrolase 1 type 2 [[cite:PUB00070175]] and, recently, through a comprehensive literature review and integrative bioinformatics analyses it was revealed that annotations for these members were misleading as they were based on a single set of in vitro results examining the NIF3 homolog of Helicobacter pylori [[cite:PUB00070175]]. Actually, they have varied phenotypes with the unifying functional role as metal-binding proteins [[cite:PUB00100327]]. This entry contains several NIF3 (NGG1p interacting factor 3) protein homologues. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown [[cite:PUB00002954],[cite:PUB00019927]].","id":"Pfam:PF01784","interpro_id":"InterPro:IPR002678","name":"Duf34/NIF3 (NGG1p interacting factor 3)","pfam_id":"PF01784","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"KNOWN_HISTORICAL_DUF","short_name":"DUF34_NIF3","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01784"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF01784.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"15cd773525152192e03934b4f5baf25e24b441933fd914a82283cad762550ed0"}},"protein_examples":{"candidate_count":7,"discovery_scanned":true,"example_count":7,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/localization/go/cell-pole-go0060187.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0060187","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/localization/go/cell-pole-go0060187.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:TIGR00486","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/type-2-gtp-cyclohydrolase-i-nf008064.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:NF008064","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/type-2-gtp-cyclohydrolase-i-nf008064.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf34-nif3-pf01784.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01784","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf34-nif3-pf01784.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR036069","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.40.1390.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P0AFP6","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF01784"],"protein_name":"NIF3-like metal-binding protein YbgI","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"2ae7b83d5e346027676294a068fdc1fb9180d32c1d525133797aea1fed9feb88","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MKNTELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTASQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDAHPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDTGPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHATERGGIRALSEWLNENTDLDVTFIDIPNPA","sequence_length":247,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"2ae7b83d5e346027676294a068fdc1fb9180d32c1d525133797aea1fed9feb88","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P0AFP6.json","taxon_id":"83333","uniprot_accession":"P0AFP6","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:TIGR00486","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR036069","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.40.1390.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml"}],"pfam_ids":["PF01784"],"protein_name":"NGG1-interacting factor 3","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSRAITRAQLDKLVRSITKFYPQKYADKSWDNTGLLIDCSTAQVTTADANAKTKVLLTVDLTKSVAQEAVDANCNVIVAYHPFIFPSWNRLSPHTNPQHETAIKLIQYGISVYCPHTAVDAARGGVNDWLVRGLNNGENVAKSYALETVSGETDDLIGYGRFVEFNKDISLEQIVKNVKRVLRVPYVQVASLAAPSAWNQLKIKKVAVCAGSGSGVFKQLKEDVDLYYTGEMSHHEVLKWKEMGKTVIVCNHSNTERGFLQDVMKGLLQDEGHEVVVSKMDCDPLTVA","sequence_length":288,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"5ec34cf6d3970d1821da76910312889219597cc7d3822579216e20a3aa385138","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P53081.json","taxon_id":"559292","uniprot_accession":"P53081","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacillus subtilis (strain 168)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:TIGR00486","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR036069","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.40.1390.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml"}],"pfam_ids":["PF01784"],"protein_name":"NIF3-like metal-binding protein YqfO","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MAKSVNGQQIIQLFEQFSPKAYAVEGDKIGLQIGTLNKPIKNVMVTLDVLESVIDEAIEKEVDLIIAHHPPIFRSLKHISTDQPAGRLIEKCLKHDIAVYAAHTNLDVADGGVNDLLAEALELSETEVLAPTYTDPLKKLAVYVPKEYEEQVRAALGNAGAGHIGEYSHCAFSSEGIGSFKPLDGAKPFIGEVGELELVHEVRLETVFPKSVEKAVINAMIKSHPYEEVAYDIYPVEQTPAEKGLGRVGTLKNEMTLKEFALFVKDKLDVNGVRMVGDADSMVKKVAVLGGDGNKYIHHAKRKGADVYVTGDLYFHVAHDAMMLGLNVVDPGHYAEKIMKEGVTRKLTSMCNDKKFGVNIFVSETDTNPFTFL","sequence_length":373,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"b57b6580aeb916fb366044a3f48db7bb03cecbaf54fa3871af2b421b20a16fde","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/P54472.json","taxon_id":"224308","uniprot_accession":"P54472","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:TIGR00486","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR036069","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.40.1390.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml"}],"pfam_ids":["PF01784"],"protein_name":"NIF3-like metal-binding protein HcgD","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MKAKEIIEFIETFAPKDLAIEGDNIGLQVGDNLDKEIKKLGIALDPSLSVIKKAEKEGVDFLFTHHPLLKDPIRNFTGVIYKKLKILMENDIILYSAHTNLDICKNGLNDALAELYNLENPKPLYDNGLGRVGIFKGSFEEFLEITKKYIHKNPIVVKSKEVDDNFKLAVLSGYGLSQSSIKYVAEKADVYLSGDLTHHSKILAEELGLVVVDATHYSTEVFGLKKFKEFLSSNLDLEIISLDF","sequence_length":244,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"705127d364e1757c2363537b0e16aa61a768722ab3c13af51c3e9db82412c73a","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q58337.json","taxon_id":"243232","uniprot_accession":"Q58337","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:TIGR00486","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf34-nif3-pf01784.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01784","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf34-nif3-pf01784.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR036069","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.40.1390.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml"}],"pfam_ids":["PF01784"],"protein_name":"NIF3-like protein 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MLSSAHLVPTSVQRAQSWICRSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMDEALQKKADFILSYHPPIFRPMKHITWKTWKECLVIRALENRVAVYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPSRAPDYPTEGAHRLEFSVNRSQDLDKVMSTLRGVGGVSVTSFPARCDGEEQTRISLNCTQKTLMQVLAFLSQDRQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLAIMIERIKTHLKLSHLRLALGVGRTLESQVKVVALCAGSGGSVLQGVEADLYLTGEMSHHDVLDAASKGINVILCEHSNTERGFLSELQEMLGVHFENKINIILSETDRDPLRVV","sequence_length":376,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"8ec6de4ab1120de7cee19c340f198e223d09bb56196892e053b9341a4e02ce59","sequence_version":4,"source_url":"https://rest.uniprot.org/uniprotkb/Q9EQ80.json","taxon_id":"10090","uniprot_accession":"Q9EQ80","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:TIGR00486","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf34-nif3-pf01784.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01784","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf34-nif3-pf01784.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR036069","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.40.1390.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml"}],"pfam_ids":["PF01784"],"protein_name":"NIF3-like protein 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MLSSCVRPVPTTVRFVDSLICNSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEVLQKKADLILSYHPPIFRPMKRITWNTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGACTSRPIHPSKAPNYPTEGNHRVEFNVNYTQDLDKVMSAVKGIDGVSVTSFSARTGNEEQTRINLNCTQKALMQVVDFLSRNKQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLATMIDRIKRHLKLSHIRLALGVGRTLESQVKVVALCAGSGSSVLQGVEADLYLTGEMSHHDTLDAASQGINVILCEHSNTERGFLSDLRDMLDSHLENKINIILSETDRDPLQVV","sequence_length":377,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"ccc2025ca5d4ac8e53c622aa753c05cf7fc4e7db545988000857d52f1c276a66","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q9GZT8.json","taxon_id":"9606","uniprot_accession":"Q9GZT8","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Drosophila melanogaster","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:TIGR00486","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/nif3-like-dinuclear-metal-center-hexameric-protein-tigr00486.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR036069","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/duf34-nif3-superfamily-ipr036069.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.40.1390.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/nif3-ngg1p-interacting-factor-3-like-3-40-1390-30.yaml"}],"pfam_ids":["PF01784"],"protein_name":"NIF3-like protein 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MLRRMNTFSGQKLAAVVKELENFAPTSWAEKWDNVGLLIEPHREKQIKKILLTNDLTEPVVKEALEKEAELIISYHPPIFKPLTRITQSHWKERVVAACLANDIALYSPHTAWDKKSGGVNDWLSKAVNIISIRPLEPELGAPPGTGSGRYIETKMELSQVVESLQKRIRNSVHVALAVGHTPKTLIQSVGICAGSGASLLKGIQADLIITGEMSHHEVLEFTHNNTTVLLCNHSNSERGFLHEFCPILAKSLNEECLVFVSEVDKDPLVTVASDINKELSAFVDVYKSTSK","sequence_length":292,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"e553b2c271ee32faed65b75b092891be859a4b604c7e97c48b2da20d0e3eb5d4","sequence_version":3,"source_url":"https://rest.uniprot.org/uniprotkb/Q9NK57.json","taxon_id":"7227","uniprot_accession":"Q9NK57","uniprot_release":"2026_03"}],"pfam_id":"PF01784","short_name":"DUF34_NIF3","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}