{"cross_mech":[],"family":{"alphafold_models":1772,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This prokaryotic protein family includes CbiZ which converts adenosylcobinamide (AdoCbi) to adenosylcobyric acid (AdoCby), an intermediate of the de novo coenzyme B12 biosynthetic route [[cite:PUB00019258]].","domain_architectures":14,"interpro_id":"IPR002808","known_evidence_count":null,"matches":2701,"name":"Adenosylcobinamide amidohydrolase","partial_evidence_count":null,"pfam_id":"PF01955","proteins":2665,"proteomes":2525,"short_name":"CbiZ","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01955","structures":0,"taxa":3886,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF01955.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":1772,"domain_architectures":14,"matches":2701,"proteins":2665,"proteomes":2525,"structures":0,"taxa":3886},"curation_status":"SEEDED","description":"This prokaryotic protein family includes CbiZ which converts adenosylcobinamide (AdoCbi) to adenosylcobyric acid (AdoCby), an intermediate of the de novo coenzyme B12 biosynthetic route [[cite:PUB00019258]].","id":"Pfam:PF01955","interpro_id":"InterPro:IPR002808","name":"Adenosylcobinamide amidohydrolase","pfam_id":"PF01955","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"CbiZ","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01955"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF01955.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"7befacf1a0c286d149a4781078a737126fd317193b67e91173c3f7404b451dba"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/cbiz-pf01955.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01955","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/cbiz-pf01955.yaml"}],"pfam_ids":["PF01955"],"protein_name":"Uncharacterized protein MJ1613","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MIEKVLEMDDWKAYKIPHTVEIDGMVEETKTLIIEFKNKRKVLSTREGFKEVKYVGNHSIPVPFWDKVHNYKDYENQVLNKIGIKKEDIALLSTGANMDNLAVAKEEFDEFYVVAFTTAGAKHNAIRLGDEEADYIEKDFKTYKIVDGKIVPKEEIGTVNIILITNANLTDGAMARAIITITEAKTNAFQELNIRSTKHPELQATGTGTDNIVVVKGFGSGVDYTGGHTKMGEMIAKAVKRSVIEALIKQDKIKI","sequence_length":255,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"79143cd363cf39ad06c6f7adfaa2ebb0481d7eef7dc814e738994aa75c57e675","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q59008.json","taxon_id":"243232","uniprot_accession":"Q59008","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/cbiz-pf01955.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01955","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/cbiz-pf01955.yaml"}],"pfam_ids":["PF01955"],"protein_name":"Adenosylcobinamide amidohydrolase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MQYHIKDQTLIIKGDFEAVSTGLNGGRARVEYIFNKQVPRTFNPPSPEEFIREEARKDGIETASLGLLTAVNMEYLQVIEDDYMTAFITAGVSNCSEFRAKAGTINIILVSKARLSETALFGAIITATEAKGLALLEKGYNFLGTNTDAVIVAYETCSDSGPKSKTNQEIPYAGSSTEFGKKITEAVIKGIKAGLELRGE","sequence_length":200,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"2e602b867512d7a0ad9bf6756c564fe5005941c3b3646afb38efeff2b1369fe3","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q8Q0G3.json","taxon_id":"192952","uniprot_accession":"Q8Q0G3","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/cbiz-pf01955.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF01955","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/cbiz-pf01955.yaml"}],"pfam_ids":["PF01955"],"protein_name":"Adenosylcobinamide amidohydrolase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MFETTLHDGVLELAAPGARWLSTGWNGGDTRADRAYSITVPDDWAPDSTHEYVTDRLAAAGFAPRDDAPVLLTGVAQEHARIARCGPVAVAATAGLSNPAALPMDPDGGTLPDAKRAPPGTVNLVAATTRALDDAALSNLVAVAAEAKAATLLATAGFPGTTSDAVVVACDPGGETAPYSGSATPVGAATRACVREAVRASLDSRDAASPDSVESAAHGTTTDVQAAVFRP","sequence_length":231,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"24a1cb196bff4a4e4d9a6e7d52edc75f1ad66137a0fa4a0707de39d8cce7f671","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q9HPK9.json","taxon_id":"64091","uniprot_accession":"Q9HPK9","uniprot_release":"2026_03"}],"pfam_id":"PF01955","short_name":"CbiZ","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}