{"cross_mech":[],"family":{"alphafold_models":3423,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family has a TIM barrel-like fold with a deep C-terminal trefoil knot. The arrangement of its hydrophilic and hydrophobic surfaces are opposite to that of the classic TIM barrel proteins. It is likely to bind RNA [[cite:PUB00021971]], and may function as a methyltransferase [[cite:PUB00044735],[cite:PUB00057459]].","domain_architectures":71,"interpro_id":"IPR003750","known_evidence_count":null,"matches":4061,"name":"Putative RNA methyltransferase","partial_evidence_count":null,"pfam_id":"PF02598","proteins":3935,"proteomes":3194,"short_name":"Methyltrn_RNA_3","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF02598","structures":5,"taxa":8305,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF02598.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":3423,"domain_architectures":71,"matches":4061,"proteins":3935,"proteomes":3194,"structures":5,"taxa":8305},"curation_status":"SEEDED","description":"This family has a TIM barrel-like fold with a deep C-terminal trefoil knot. The arrangement of its hydrophilic and hydrophobic surfaces are opposite to that of the classic TIM barrel proteins. It is likely to bind RNA [[cite:PUB00021971]], and may function as a methyltransferase [[cite:PUB00044735],[cite:PUB00057459]].","id":"Pfam:PF02598","interpro_id":"InterPro:IPR003750","name":"Putative RNA methyltransferase","pfam_id":"PF02598","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Methyltrn_RNA_3","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF02598"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF02598.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"b479e7e668dbe51e1a6d1bd47c1f6eefacaad3d39aeda0d4f1c5e3369b313278"}},"protein_examples":{"candidate_count":6,"discovery_scanned":true,"example_count":6,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Drosophila melanogaster","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd18086","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF02598","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml"}],"pfam_ids":["PF02598"],"protein_name":"28S rRNA (uridine-N(3))-methyltransferase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MKTMLAAPTASSNGRPIGPHKSWKKVNEERKALKRQRKQDKLLKELQQAKEAESQAGKAANEVQAKDKPNPSTLSIAVPGSILENAQSNELRAYVAGQIARAACIFRVNEVIVFDDVGIATARETKRSYEADGEGSSTGTVRSSSLQLARILQYLECPQYLRKYFFPLHKDLKYSGLLNPLDTPHHLRQQSKFRYREGVICDKKAKEGHSYANVGLLNDVLVDKAIEPGVRVTVKMEPQSESCRKQRGTLVSPDEPRRETGVYWGYQVRIAHSMSEIFTKSPYATGYDVTVGTSDRGTNVHEVPNRSYNFNHMLIVFGGLQGLESALANDEKLTVDDPELLFDHYVNVLPRQGSRTIRTEEALLIALAALQEKLQPQVADVEIDLTDLLPKSEDSGIAVRRDVLVSKKQKKRKQVEDTPDETVVDEPSFSKPLPKVARLTANPFADSSEELAKNTPAQDDFEVVSSTTVSGTSHSCADDDLSRFD","sequence_length":485,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"4f2ef6e6072d9758a23d9c485c14bc69df5f879c14058136a5103951746d6c1a","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/A1Z830.json","taxon_id":"7227","uniprot_accession":"A1Z830","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd18086","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF02598","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P53336","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF02598"],"protein_name":"Putative methyltransferase YGR283C","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"e33b321a1c8a4e5a63127a3ed7df010034c16c7db277541baf5622b388702645","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MAVKHKSESLKHEEGAAKKAKTGLLKLKKIMDIESNVVKYSICIPTTVIDNCNNLEQVTFTAYQIARTAVLFNVQEIIVLDQSKDKKHEKKSRSKETISDCLLLATLLQYFVTPPNLLDTTFKKKNKLYLKCASTFPPLNQLPFMNASAEQHYKEGLSIARDSSKGKSDDALTNLVYIGKNQIITLSNQNIPNTARVTVDTERKEVVSPIDAYKGKPLGYHVRMASTLNEVSEGYTKIVWVNSGDFHYDEELSKYHKVETKLPYIAKLKKSSTSEKPCNILLIFGKWGHLKRCFRRSDLESSSLHHYFSGQLQFPASVPQGNIPIQDSLPIALTMFQRWAS","sequence_length":341,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"e33b321a1c8a4e5a63127a3ed7df010034c16c7db277541baf5622b388702645","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P53336.json","taxon_id":"559292","uniprot_accession":"P53336","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd18086","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF02598","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml"}],"pfam_ids":["PF02598"],"protein_name":"Putative methyltransferase YMR310C","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSSTRKFKKVEKPLSQTRHYSLCIPTTLVSDCRNLSQITHKVYQVAKFASLFNVSEVVILEDNSQVDATKKKISTAKLILALLQYFVTPPYLRNTVFNEKFRPYLTAASKLPRLSTLPFTRYQKQDHGRYREGLTIKMQKPTLARKKIGKVFKQTKYINIGKSKALALQSQLVPINARVTIDTITRKIVSPQEAYGDFTGLDSQYGYYTRIASSFTDLFMKGPLKEGYTQSVYVPLTTRDTSIPELSSLPTAETNPHILLVFSTWDTLARAFKLDQDQFVDCQGPQEFFDAQLPCPVSNSDVADAIPMTLTTLSTVF","sequence_length":317,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"95287775c1ebc859bbcf4795c20928cb5d84a08a97f872e5918d341da77dfd3e","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q04867.json","taxon_id":"559292","uniprot_accession":"Q04867","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Caenorhabditis elegans","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd18086","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF02598","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml"}],"pfam_ids":["PF02598"],"protein_name":"Putative methyltransferase spot-1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MHPDQKKTFKEKNDIRKKLFNSTKEERLDWRKMKDEKKRKNEEKIIKEAEEAKKAKIEKVDHTPPFTISIAVPGQFLNNAQSAELRTYMAGQIARAATLYRVDEIIIYDESCRMTDEAVNAYYNGTWQGNLIPAETNYEGCFYLAKILEYLECPQYLRKDLFPIQKPLKNAGLLNPLDAQHHLKYDEKTLRFREGVVLKKRSKDGRGPICNIGLEKEFEIDSDAVQLPPYTRVTVEIKNLTEQCKLYRGSITSGATVTRETGLYWGYSVRLMTGLQKVLQAKKFDIVAGVSPRGKLASQMDVCILNKPKILLVFGGVAGVDAAVESEELAEWRRAEDAFDVLIRTTSLSNGSRSERVEENVLSVLAQVQCHLETLNAL","sequence_length":378,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"cc753ee4c2dd451ab289e93efb027a95b74f9bc0e6ce06f3bee70f1f7239986a","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q10950.json","taxon_id":"6239","uniprot_accession":"Q10950","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/rrna-uridine-n3-methyltransferase-activity-go0070042.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0070042","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/rrna-uridine-n3-methyltransferase-activity-go0070042.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd18086","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF02598","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/alpha-beta-knot-methyltransferases-ipr029028.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR029028","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/alpha-beta-knot-methyltransferases-ipr029028.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/trna-guanine-n1-methyltransferase-n-terminal-ipr029026.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR029026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/trna-guanine-n1-methyltransferase-n-terminal-ipr029026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/spout-methyltransferase-trefoil-knot-domain-3-40-1280-10.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.40.1280.10","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/spout-methyltransferase-trefoil-knot-domain-3-40-1280-10.yaml"}],"pfam_ids":["PF02598"],"protein_name":"28S rRNA (uridine-N(3))-methyltransferase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MAERPRKRPCGPGEHGQRVEWRKWKQQKKEEKKKWKDLKIMKKLERQRAQEEEAKRQEEEEEAAAQRSNQGRPYTLSVALPGSILDNAQSPELRTYLAGQIARACTIFCVDEIVVFDEEGQDTKSVEGEFRGVGKKGQACVQLARILQYLECPQYLRKAFFPKHQDLQFAGILNPLDSPHHMRQDEESEFREGVVVDRPTKAGHGSLVNCGMKKEVKIDKKLDPGLRVTVRLNQQQLPECKTYKGTVVSSQDPRTKAGLYWGYTVRLASCLSAVFAEAPFQDGYDLTIGTSERGSDVASAQLPSFRHALVVFGGLQGLEAAVDADPNLEVADPSVLFDFYVNTCLSQGSRTIRTEEAILISLAALQPGLTQVGSRPASPLSGPRM","sequence_length":385,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"a0a4a5e683687323f31f3d7e8a8c987b29bb2de10baeed594a478dd245903dc4","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q3UHX9.json","taxon_id":"10090","uniprot_accession":"Q3UHX9","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/rrna-uridine-n3-methyltransferase-activity-go0070042.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0070042","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/rrna-uridine-n3-methyltransferase-activity-go0070042.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd18086","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/spout-superfamily-rna-methyltransferase-hsc9orf114-like-human-c9orf114-cd18086.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF02598","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/methyltrn-rna-3-pf02598.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/alpha-beta-knot-methyltransferases-ipr029028.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR029028","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/alpha-beta-knot-methyltransferases-ipr029028.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/trna-guanine-n1-methyltransferase-n-terminal-ipr029026.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR029026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/trna-guanine-n1-methyltransferase-n-terminal-ipr029026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/spout-methyltransferase-trefoil-knot-domain-3-40-1280-10.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.40.1280.10","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/spout-methyltransferase-trefoil-knot-domain-3-40-1280-10.yaml"}],"pfam_ids":["PF02598"],"protein_name":"28S rRNA (uridine-N(3))-methyltransferase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MAERGRKRPCGPGEHGQRIEWRKWKQQKKEEKKKWKDLKLMKKLERQRAQEEQAKRLEEEEAAAEKEDRGRPYTLSVALPGSILDNAQSPELRTYLAGQIARACAIFCVDEIVVFDEEGQDAKTVEGEFTGVGKKGQACVQLARILQYLECPQYLRKAFFPKHQDLQFAGLLNPLDSPHHMRQDEESEFREGIVVDRPTRPGHGSFVNCGMKKEVKIDKNLEPGLRVTVRLNQQQHPDCKTYHGKVVSSQDPRTKAGLYWGYTVRLASCLSAVFAEAPFQDGYDLTIGTSERGSDVASAQLPNFRHALVVFGGLQGLEAGADADPNLEVAEPSVLFDLYVNTCPGQGSRTIRTEEAILISLAALQPGLIQAGARHT","sequence_length":376,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"92184d205b2594b62a641066f5969fc4b2d12efda05ecea0a3360df401e8a0ca","sequence_version":3,"source_url":"https://rest.uniprot.org/uniprotkb/Q5T280.json","taxon_id":"9606","uniprot_accession":"Q5T280","uniprot_release":"2026_03"}],"pfam_id":"PF02598","short_name":"Methyltrn_RNA_3","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}