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This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2 [[cite:PUB00078085]].","domain_architectures":4,"interpro_id":"IPR010149","known_evidence_count":null,"matches":568,"name":"Csm2 Type III-A","partial_evidence_count":null,"pfam_id":"PF03750","proteins":564,"proteomes":541,"short_name":"Csm2_III-A","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF03750","structures":48,"taxa":1553,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF03750.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":432,"domain_architectures":4,"matches":568,"proteins":564,"proteomes":541,"structures":48,"taxa":1553},"curation_status":"SEEDED","description":"Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins [[cite:PUB00043286]]. 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