{"cross_mech":[],"family":{"alphafold_models":1835,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"Members of this family contain a conserved core of four predicted transmembrane segments. Some members have an additional pair of N-terminal transmembrane helices. This family includes lysine exporter LysO (YbjE) from E. coli [[cite:PUB00075629]].","domain_architectures":2,"interpro_id":"IPR005642","known_evidence_count":null,"matches":2703,"name":"Lysine exporter LysO","partial_evidence_count":null,"pfam_id":"PF03956","proteins":2618,"proteomes":2006,"short_name":"Lys_export","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF03956","structures":0,"taxa":3232,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF03956.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":1835,"domain_architectures":2,"matches":2703,"proteins":2618,"proteomes":2006,"structures":0,"taxa":3232},"curation_status":"SEEDED","description":"Members of this family contain a conserved core of four predicted transmembrane segments. Some members have an additional pair of N-terminal transmembrane helices. This family includes lysine exporter LysO (YbjE) from E. coli [[cite:PUB00075629]].","id":"Pfam:PF03956","interpro_id":"InterPro:IPR005642","name":"Lysine exporter LysO","pfam_id":"PF03956","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Lys_export","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF03956"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF03956.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"f5fed99d46f7cfe6d907f5505493e0d989cea9e9ed67d8aac2889f5c640cdf7d"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/l-lysine-efflux-transmembrane-transporter-activity-go0015661.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0015661","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/l-lysine-efflux-transmembrane-transporter-activity-go0015661.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/lys-export-pf03956.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF03956","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/lys-export-pf03956.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P75826","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF03956"],"protein_name":"Lysine exporter LysO","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"f10ce10c3814aca4fe2e035ad5ffc1580eff3157cab3b07d4975a0934e29904b","sequence_version":2,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MFSGLLIILVPLIVGYLIPLRQQAALKVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVVSSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA","sequence_length":299,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"f10ce10c3814aca4fe2e035ad5ffc1580eff3157cab3b07d4975a0934e29904b","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/P75826.json","taxon_id":"83333","uniprot_accession":"P75826","uniprot_release":"2026_03"}],"pfam_id":"PF03956","short_name":"Lys_export","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}
