{"cross_mech":[],"family":{"alphafold_models":4505,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This is a family of glycosyl-hydrolases of the CAZy GH130 family. Several have been characterised as mannosylglucose phosphorylase [[cite:PUB00068792],[cite:PUB00068791],[cite:PUB00109137]]. This enzyme is part of the mannan catalytic pathway and feeds into the glycolysis cycle [[cite:PUB00068792]]. Specifically it catalyses the reversible phosphorolysis of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine [[cite:PUB00109137]]. This family was noted to belong to the Beta fructosidase superfamily in [[cite:PUB00015849]].","domain_architectures":27,"interpro_id":"IPR007184","known_evidence_count":null,"matches":6975,"name":"beta-1,4-mannooligosaccharide phosphorylase","partial_evidence_count":null,"pfam_id":"PF04041","proteins":6736,"proteomes":3640,"short_name":"Glyco_hydro_130","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04041","structures":33,"taxa":5878,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF04041.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":4505,"domain_architectures":27,"matches":6975,"proteins":6736,"proteomes":3640,"structures":33,"taxa":5878},"curation_status":"SEEDED","description":"This is a family of glycosyl-hydrolases of the CAZy GH130 family. Several have been characterised as mannosylglucose phosphorylase [[cite:PUB00068792],[cite:PUB00068791],[cite:PUB00109137]]. This enzyme is part of the mannan catalytic pathway and feeds into the glycolysis cycle [[cite:PUB00068792]]. Specifically it catalyses the reversible phosphorolysis of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine [[cite:PUB00109137]]. This family was noted to belong to the Beta fructosidase superfamily in [[cite:PUB00015849]].","id":"Pfam:PF04041","interpro_id":"InterPro:IPR007184","name":"beta-1,4-mannooligosaccharide phosphorylase","pfam_id":"PF04041","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Glyco_hydro_130","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04041"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF04041.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"76d647a39e87d34df407223f812b779fb6afae139333b9371d87b77669df187a"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Hominimerdicola alba (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 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E50)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/repeat/pfam/glyco-hydro-130-pf04041.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04041","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/repeat/pfam/glyco-hydro-130-pf04041.yaml"}],"pfam_ids":["PF04041"],"protein_name":"1,4-beta-mannosyl-N-acetylglucosamine 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phosphorylase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MNIYRYEENPLITPLDVKPIHEGFEVIGAFNGGVAEYNGEVLLLLRVAEKPVSEDPEIVLAPVYNAKNKELELQSFRLDDENYDFEDPRMIRSKAKLEGFSYLTSLSYIRIARSKDGHHFTLDEKPFLYPFNEYQTFGIEDARVTQIGDTYHVNFSAVSEFGVADALVTTKDFENLEYQGNIFAPENKDVLIFPEKINGKYYALHRPSLKSIGNLDIWIASSPDLRSFGDHRHLLGIRPGEYDSGRVGGGCVPIKTEEGWLILYHGATEENRYVMGAALLDLNDPTIVLKRTKTPILEPVADYEKNGFFGDVVFACGAIQEGDTLHMYYGVADTSMAGCDMKISEILHQLEVEAK","sequence_length":355,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"193fef85793a058da564a5531fccbd39552bb5007c506fff4f95cc0975ff11c9","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q92DF6.json","taxon_id":"272626","uniprot_accession":"Q92DF6","uniprot_release":"2026_03"}],"pfam_id":"PF04041","short_name":"Glyco_hydro_130","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}