{"cross_mech":[],"family":{"alphafold_models":389,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain has a cyclophilin-like fold, consisting of an eight-stranded beta-barrel with an alpha helix located between the beta-2 and beta-3 strands and a 310 helix located between the beta-7 and beta-8 strands. The catalytic site found in human cyclophilin is not conserved in this domain, suggesting a different function for this domain [[cite:PUB00039053],[cite:PUB00048358]].","domain_architectures":6,"interpro_id":"IPR025658","known_evidence_count":null,"matches":565,"name":"Cyclophilin-like","partial_evidence_count":null,"pfam_id":"PF04126","proteins":564,"proteomes":531,"short_name":"Cyclophil_like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04126","structures":3,"taxa":1025,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF04126.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":389,"domain_architectures":6,"matches":565,"proteins":564,"proteomes":531,"structures":3,"taxa":1025},"curation_status":"SEEDED","description":"This domain has a cyclophilin-like fold, consisting of an eight-stranded beta-barrel with an alpha helix located between the beta-2 and beta-3 strands and a 310 helix located between the beta-7 and beta-8 strands. The catalytic site found in human cyclophilin is not conserved in this domain, suggesting a different function for this domain [[cite:PUB00039053],[cite:PUB00048358]].","id":"Pfam:PF04126","interpro_id":"InterPro:IPR025658","name":"Cyclophilin-like","pfam_id":"PF04126","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Cyclophil_like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04126"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF04126.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"b66cb5fc6a8dae76eadef5d6d1ebc1e22ca8fbe3215423a83c71c8d3a98761eb"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF04126","short_name":"Cyclophil_like","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}