{"cross_mech":[],"family":{"alphafold_models":8752,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This is the AlbA_2 domain from the Schlafen (SLFN) family of proteins which are important in cell differentiation and defense against viruses [[cite:PUB00151569],[cite:PUB00151570]]. This domain is present at the N-terminal of all SLFN proteins and includes the SLFN box, a sequence unique to these proteins that may form a dimer interface [[cite:PUB00151569]]. The AlbA_2 domain is RNA-binding and RNase region as it contains the highly conserved catalytic glutamic acid residues [[cite:PUB00151569]].","domain_architectures":234,"interpro_id":"IPR007421","known_evidence_count":null,"matches":12943,"name":"Schlafen, AlbA_2","partial_evidence_count":null,"pfam_id":"PF04326","proteins":12925,"proteomes":7286,"short_name":"SLFN_AlbA_2","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04326","structures":31,"taxa":13051,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF04326.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":8752,"domain_architectures":234,"matches":12943,"proteins":12925,"proteomes":7286,"structures":31,"taxa":13051},"curation_status":"SEEDED","description":"This is the AlbA_2 domain from the Schlafen (SLFN) family of proteins which are important in cell differentiation and defense against viruses [[cite:PUB00151569],[cite:PUB00151570]]. This domain is present at the N-terminal of all SLFN proteins and includes the SLFN box, a sequence unique to these proteins that may form a dimer interface [[cite:PUB00151569]]. The AlbA_2 domain is RNA-binding and RNase region as it contains the highly conserved catalytic glutamic acid residues [[cite:PUB00151569]].","id":"Pfam:PF04326","interpro_id":"InterPro:IPR007421","name":"Schlafen, AlbA_2","pfam_id":"PF04326","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"SLFN_AlbA_2","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04326"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF04326.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"4877d37649a08e526c5686e0b281cfbaa88f44ff63a1dc2dd6c57216ac439bbc"}},"protein_examples":{"candidate_count":15,"discovery_scanned":true,"example_count":15,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Monkeypox virus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/baculo-p26-pf04766.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF04766","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/baculo-p26-pf04766.yaml"}],"pfam_ids":["PF04326","PF04766","PF17057"],"protein_name":"Poxin-Schlafen","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MFYAHAFGGYDENLHAFPGISSTVANDVRKYSVVSVYNKKYNIVKNKYMWCNSQVNKRYIGALLPMFECNEYLQIGDPIHDLEGNQISIVTYRHKNYYALSGIGYESLDLCLEGVGIHHHVLETGNAVYGKVQHEYSTIKEKAKEMNALKPGPIIDYHVWIGDCVCQVTTVDVHGKEIMRMRFKRGAVLPIPNLVKVKVGEENDTINLSTSISALLNSGGGTIEVTSKEERVDYVLMKRLESIHHLWSVVYDHLNVVNGEERCYVHMHSSHQSPMLSTVKTNLYMKTMGACLQMDSMEALEYLSELKESGGRSPRPELQKFEYPDGVKDTESIERLAEEFFNRSELQAGESVKFGNSINVKHTSVSAKQLRTRIRQQLPSILSSFANTKGGYLFIGVDNNTHKVIGFTVGHDYLKLVESDIEKYIQKLPVVHFCKKKEDIKYACRFIKVYKPGDETTSTYVCAIKVERCCCAVFADWPESWYMDTSGSMKKYSPDEWVSHIKF","sequence_length":503,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"baf1de926137511d35bf2ac38a9ae0749eee1b928077ce8ec712b1c668f251fa","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/A0A7H0DNF0.json","taxon_id":"10244","uniprot_accession":"A0A7H0DNF0","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR031450","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-group-3-like-dna-rna-helicase-domain-ipr018647.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018647","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-group-3-like-dna-rna-helicase-domain-ipr018647.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR048729","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/uvrd-like-helicase-c-terminal-domain-ipr027785.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR027785","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/uvrd-like-helicase-c-terminal-domain-ipr027785.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-g3-helicase-pf09848.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF09848","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-g3-helicase-pf09848.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF21026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/uvrd-c-2-pf13538.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF13538","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/uvrd-c-2-pf13538.yaml"}],"pfam_ids":["PF04326","PF09848","PF13538","PF17057","PF21026"],"protein_name":"Schlafen family member 9","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"METYLSLVVKRSYPDLIIYAGEVTLGEKVRNKKDSKKRKLEKTRITQAACALLNSGGGVIVIQMANQSEQPERMGQDLETSLRNLIPSLDLQAFFETKQQEDKFYIFVKSWSSSPEDDSTKPRICSLGTSLYCRSLTSKVAMDSRDAFYFLKKKKAYIKCSPTDDRAPPAKIPRTMSQKSLESNPAFEIFQSKKLEYGQRLLFSESTSIEFKQFDTENAQKYMKDIIPEYISAFANTQGGYLFIGVDDKSIILGCPKDNVDPDSLKIVANEAISKLPVFHFCSSKDKNKVSYETRVIDVFQEGNLYGYLCVIKVEPFCCAVFSEAPISWMVDKEKGVYTLNTEEWVRMMVDVGPEAASNDLSRDFECQLSLSDSPPHCRPVYSKKGLEHKVDLQQRLFQVSPDCLKYTPESLWSELCSQHERLEDLVKQQIRSFSCGLLILSRSWAVDLNLEEKQEVICDALLIAQNSPPILYTILGEQDEQGQDYCTRTAFTLKQKLVNTGGYTGRVCVMTKVLCLSSQNNNKTSGGSVSPIDYPSSYNLANIQEMQGLLQALVIVLLNFRSFLSDQLGCEVLNLLTAQQYEILSKSLRKTRELFVHGLPGSGKTIIAMKIMEKIRNTFHCETDRILYICENQPLRDFIQAKNICQAVTRKTFMNYKFKTERFQHIIIDEAQNFRTEDGNWYEKAKGITRGMKNCPGILWIFLDYFQTSHLQESGLPDFSLQYPKEELTQVVRNADKIAEFLQQELQKIRDNPPCSIPQESLNILHEFKWSQGVSGTYEITYLTLEKMVSYITDKCDVFLSKGYSPQDIAVLFSTDREKKAYEHMFLREMRKRRRASHMNDESVCHSNMFDSIRRFSGLERSIVFGINPIATEQPISHNLLLCLASRAMKHLYILYLSTPEGQSSMVAC","sequence_length":910,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"331126e90b40760a67ffe8e33c2c16ec3f2a4018707de87bcfe9a21b4cdcbf86","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/B1ARD6.json","taxon_id":"10090","uniprot_accession":"B1ARD6","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/trna-decay-go0016078.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0016078","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/trna-decay-go0016078.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR031450","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-group-3-like-dna-rna-helicase-domain-ipr018647.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018647","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-group-3-like-dna-rna-helicase-domain-ipr018647.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR048729","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/uvrd-like-helicase-c-terminal-domain-ipr027785.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR027785","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/uvrd-like-helicase-c-terminal-domain-ipr027785.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-g3-helicase-pf09848.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF09848","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-g3-helicase-pf09848.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF21026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/uvrd-c-2-pf13538.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF13538","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/uvrd-c-2-pf13538.yaml"}],"pfam_ids":["PF04326","PF09848","PF13538","PF17057","PF21026"],"protein_name":"Schlafen family member 8","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"METHPSLAVKWSCPDLTIYAGEVTIGEEDRNKMDSKKRKLEKTRITEAACALLNSGGGLIAMQMTNKSEHPVEMGQDLEKSLRELIMSPNMQAFFETKQQEDQFYIFVKSWSCRPEDGSTKPRICSLGSSLYCRSITSKVAMDSREAFEFLKDKKACIKYRPTDDGAPPAKIPRAMCQNSLESNPAFEIFQSKKLEYGQCLLFSESTSIEFKQFSTKHVQAYMKNIIPEYISAFANTQGGYLFIGVDDKRIILGCPKDNVDRDSLKTVANETISKVPVFHFCSSKDKDKVSYETRVIDVFQEGNLYGYLCVIKVEPFCCAVFSEAPISWMVDKEKGVYRLNTEEWVRMMVDFGPEASSKDLSKDFECQLSLCNSPPHCRPVYSKKGLQHKVDLQQRLFQVSPDCLKYTPESLWKELCSQHKRLKGLVKQQIRSFSCGLLILYRSWAVDLNLKEKQEVICDALLIAQNSPPILYTILGEQDEQGQDYCNHTAFTLKQKLVNTGGYTGRVCVMTKVLCLSSQNNIETNGGSVSPINYPSSYNLANIQEMQDLLQALVIVLLNFRSFLSDQLGCEILNLLTAQQYEILSKSLRKTRELFVHGLPGSGKTIIAMKIMEKIRNTFHCETDSILYICENQPLRDFIRAKRICQAVTRKTFMNYRFKTNSFQHIIVDEAQNFRTEDGNWYGKAKAISRRVKSCPGMFWIFLDYFQTSHLKESGLPDFSRQYPREELTQVVRNGDKIAEFLQKELQKIRDNPPCSIPRQSLNIVHEFKWSQSVSGNIKTEQFTLEDMVIYVADKCYDFLRKGYSLQDIAVLFSTDKEKKTYESMFLGEMRKRRRASEMNHAYLCDSNMFDSIRRFSGLERSIVFGINPIATEQPISHNLLLCLASRAMKHLYILYFSTPEGHSSTEAC","sequence_length":910,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"5bf6d697cf391edb596a2b8489b8dbaa53e2a71940cc4a611ff31e68559396f1","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/B1ARD8.json","taxon_id":"10090","uniprot_accession":"B1ARD8","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/platelet-maturation-go0036345.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0036345","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/platelet-maturation-go0036345.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR031450","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007421","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR048729","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04326","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF21026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038461","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.30.950.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P0C7P3","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF04326","PF17057","PF21026"],"protein_name":"Protein SLFN14","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"94ccd23b3ac6fe07f010ef5d7b1d0c59cef267c925ab0c2f76c2c39dd0ceec5f","sequence_version":2,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MESLKTDTEMPYPEVIVDVGRVIFGEENRKKMTNSCLKRSENSRIIRAICALLNSGGGVIKAEIDDKTYSYQCHGLGQDLETSFQKLLPSGSQKYLDYMQQGHNLLIFVKSWSPDVFSLPLRICSLRSNLYRRDVTSAINLSASSALELLREKGFRAQRGRPRVKKLHPQQVLNRCIQEEEDMRILASEFFKKDKLMYKEKLNFTESTHVEFKRFTTKKVIPRIKEMLPHYVSAFANTQGGYVLIGVDDKSKEVVGCKWEKVNPDLLKKEIENCIEKLPTFHFCCEKPKVNFTTKILNVYQKDVLDGYVCVIQVEPFCCVVFAEAPDSWIMKDNSVTRLTAEQWVVMMLDTQSAPPSLVTDYNSCLISSASSARKSPGYPIKVHKFKEALQRHLFPVTQEEVQFKPESLCKKLFSDHKELEGLMKTLIHPCSQGIVIFSRSWAGDVGFRKEQNVLCDALLIAVNSPVVLYTILIDPNWPGGLEYARNTAHQLKQKLQTVGGYTGKVCIIPRLIHLSSTQSRPGEIPLRYPRSYRLADEEEMEDLLQALVVVSLSSRSLLSDQMGCEFFNLLIMEQSQLLSESLQKTRELFIYCFPGVRKTALAIKIMEKIKDLFHCKPKEILYVCESDSLKDFVTQQTTCQAVTRKTFMQGEFLKIKHIVMDETENFCSKYGNWYMKAKNITHPKAKGTGSENLHHGILWLFLDPFQIHHADVNGLPPPSAQFPRKTITSGIHCALEIAKVMKEEMKRIKENPPSNMSPDTLALFSETAYEEATCAQALPGVCETKTNLTTEQIANYVARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLALLKAMELIETHRPSEVVFSPATGVWGSHIVLDSIQQFSGLERTVVFGLSPECDQSEEFHKLCFASRAIKHLYLLYEKRAAY","sequence_length":912,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"94ccd23b3ac6fe07f010ef5d7b1d0c59cef267c925ab0c2f76c2c39dd0ceec5f","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/P0C7P3.json","taxon_id":"9606","uniprot_accession":"P0C7P3","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Caenorhabditis elegans","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/localization/go/endoribonuclease-complex-go1902555.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:1902555","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/localization/go/endoribonuclease-complex-go1902555.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/spry-domain-associated-with-dead-box-gene-ddx1-this-spry-domain-is-ass-cd12873.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd12873","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/spry-domain-associated-with-dead-box-gene-ddx1-this-spry-domain-is-ass-cd12873.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007421","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04326","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038461","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.30.950.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml"}],"pfam_ids":["PF00622","PF04326"],"protein_name":"Schlafen-like protein 2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MADTSPRESKLNKQDQDLHLEIDETGLACKSEVKKRWLGARGTAGLYGNGKYYYEVTITSKGLCRVGWATLGGSLNIGKGLDSFGYGGTGMKSTHKKFDDYGLPFTLNDVIGCYLDLDSRTIWWSKNGEQFPAAFSIDVKYKNSNTCLFPAVLCQNSSLSVNFGSQPFKFPPGNQFTAVSDAPNENVNWWSYEEQNSFEHVVVKLPFAVEEDVHNEFRMHTKLMLTELKRTQCKQDKDGSIRRTLQPISKTICAFLNTDGGRLFLGVNDDKVIKGISMSKNMIYHFFGSLRHMCENFKPCSPLCRIKVSILEVIPVGVIKVKLRKADLLKEEAHDFPKLACHSVGGSFCDCFLEINKAPTKQYLLIIQVSPPNPNSRTTIFQNEEGLVYRRRMASNKCVYLDDLRRMMNEKNQVFVDLPDEARAEIDSFSKFD","sequence_length":433,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"670767b296dde36231edb7129a0475e89c57a4d5f65c8b7a56a20653d4cd6d38","sequence_version":3,"source_url":"https://rest.uniprot.org/uniprotkb/Q19614.json","taxon_id":"6239","uniprot_accession":"Q19614","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007421","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04326","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038461","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.30.950.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml"}],"pfam_ids":["PF04326"],"protein_name":"Schlafen-like protein 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MTPMKRSVQTQVSEPFMESWGEESLPELPAEQSLTEYSDLEEAPSAHTLYVGHLNPQFSVPVLACLLRDTLERLEMPVAREHIEVVRRPRKAYALVQVTVHRDTLASLPWRLQTALEEHLILKELAARGKDLLLSEAQGPFSHREEKEEEEEDSGLSPGPSPGSGVPLPTWPTHTLPDRPQAQQLQSCQGRPSGVCSDSAIVHQQIVGKDQLFQGAFLGSETRNMEFKRGSGEYLSLAFKHHVRRYVCAFLNSEGGSLLVGVEDSGLVQGIRCSHRDEDRARLLVDSILQGFKPQIFPDAYTLTFIPVISTSETSVPLKVIRLTVHTPKAQSQPQLYQTDQGEVFLRRDGSIQGPLSASAIQEWCRQRWLVELGKLEEKMKALMMEKEQLQQQLQQHGPVSCTCCVL","sequence_length":407,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"dc9b98b2ab881c7bfd7f25b8892c1e6e5ff1327716881b9c682d2ff0d13ab32b","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q499Z3.json","taxon_id":"9606","uniprot_accession":"Q499Z3","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-group-3-like-dna-rna-helicase-domain-ipr018647.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018647","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-group-3-like-dna-rna-helicase-domain-ipr018647.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR048729","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-g3-helicase-pf09848.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF09848","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-g3-helicase-pf09848.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF21026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/b3r-pf17057.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF17057","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/b3r-pf17057.yaml"}],"pfam_ids":["PF04326","PF09848","PF17057","PF21026"],"protein_name":"Schlafen family member 13","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MEANHCSLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGVIQMEMANRDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKDGSFNSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVYQNISESNPAYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFANTEGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIVEVFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPPDFAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRETFLREKFEHIQHIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHSGLPPLSAQYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGVPGNTKIIKNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKKMVVQLSDACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHLYIFL","sequence_length":897,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"97eea6d24965e0f344d0713c3317c3ae3b0059627f51e42cb5da20d300edfbdd","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q68D06.json","taxon_id":"9606","uniprot_accession":"Q68D06","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR048729","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF21026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml"}],"pfam_ids":["PF04326","PF17057","PF21026"],"protein_name":"Schlafen family member 12-like","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MDLARKEFLRGNGLAAGKMNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEALAADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVGLNEDKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEELPSPASTSSPVSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKDLEKALSNILPKENQIFLFVCLFRFCLFVCWFVCFFLR","sequence_length":588,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"84937552e414af828ad63fb2527a92daaa4e735818c518b23530f8ecfd1a6829","sequence_version":4,"source_url":"https://rest.uniprot.org/uniprotkb/Q6IEE8.json","taxon_id":"9606","uniprot_accession":"Q6IEE8","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR031450","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007421","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-group-3-like-dna-rna-helicase-domain-ipr018647.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018647","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-group-3-like-dna-rna-helicase-domain-ipr018647.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR048729","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04326","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-g3-helicase-pf09848.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF09848","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-g3-helicase-pf09848.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF21026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/b3r-pf17057.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF17057","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/b3r-pf17057.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038461","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.30.950.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml"}],"pfam_ids":["PF04326","PF09848","PF17057","PF21026"],"protein_name":"Schlafen family member 11","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MEANQCPLVVEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGVIRMAKKVEHPVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPRLCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPKILEEGPFHKIHKGVYQELPNSDPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLWRDLISEHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKTFLRENFEHIQHIVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCSGLPPLSDQYPREELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGVQGTLRIKKYLTVEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKKRVVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHLYIFPWGGH","sequence_length":901,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"bb033ffe57b7807f4f35bce26f723a308909f7e17e5897e829a0ef00452dd0e6","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q7Z7L1.json","taxon_id":"9606","uniprot_accession":"Q7Z7L1","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007421","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04326","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038461","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.30.950.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml"}],"pfam_ids":["PF04326"],"protein_name":"Schlafen-like protein 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSLRKRSAQTQMWESPVMSQGKQSLLELPLKESPPKDSGLKAVPSTHTLYVSHLNPQFSVPVLACLLRDTLERLELPVARGQIEVVRRPRNTYALVQVAAPKAVLASLPWRLQMALEEQLILKELTARGKELVLSEALESLHHREQEDSGPSPSHSPGPSPGPSPGLRHPPLPQLADPSPIWGSAGRRQISQNRPSGVRSDSAIVHHKILGQEQLFQGAFLGSETRNMEFKRGSGEYLSLAFKHHVRRYVCAFLNSEGGSLLVGVEDSGLVQGIHCSHRDEDRTRLLVDSILQGFKPQVFPDAYTLTFIPVISTTTTSTPLKVLRLTVHTPKAQGEPQLYETDQGEVFLRRDGSIQGPLSVGAIQDWCRQKWAMELGKLEEKVKVLTLEKEQLQQQLRQRQPLSCSCCVL","sequence_length":410,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"a4bd0dacf74a14707226365ab45f475f7e9df2492454958af2696e9efe850e12","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q8BHW9.json","taxon_id":"10090","uniprot_accession":"Q8BHW9","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-group-3-like-dna-rna-helicase-domain-ipr018647.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR018647","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-group-3-like-dna-rna-helicase-domain-ipr018647.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/uvrd-like-helicase-c-terminal-domain-ipr027785.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR027785","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/uvrd-like-helicase-c-terminal-domain-ipr027785.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-g3-helicase-pf09848.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF09848","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-g3-helicase-pf09848.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/uvrd-c-2-pf13538.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF13538","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/uvrd-c-2-pf13538.yaml"}],"pfam_ids":["PF04326","PF09848","PF13538","PF17057","PF21026"],"protein_name":"Schlafen family member 5","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSFLEDLELNFAECIQDGGKATLGVRQREEMDTTHCMKQNEIISQAVCALLNSGGGVVRVEIENGDYNFERDGVGLNLPPLFRNHLDEMLYGKLFLIYVSSWDVAASHVRLATLCSNLYHRCGTFTEVMDPEKALKFLKRVQDPRILGDSDSLNLQEAPVDDAQMILASDLFHSPQLQYLEKLNFTKSSHVEFQMFSADLSQGIRERLPKCVSALANSEGGYVFFGVHDETRHVIGCEKEKINCTNLKSTIDACIRKMPVYHFCGQNHKVQYELKFLEVYDKEALHGYVCAIKVERFCCAAFAKAPDSWEIKDNNKKPLTANDWASRMIEINPDLSSFPQMIPWKSMLNTTPCSKTVFTHKYLKCVEDLQKDYFPVSPNRITYTPESVYKDLFADYRGLRNLINMEMRCFSQGILIFSHSWAVDLGLQRRQDVICDALLISPNNVPILYTICNKWDLGNRHYSMKVARTLKQKLVNMGGYPGRLGIIPLVLPLGSHQRVRNDLEMPVYPESYNFITTQQVEALLQSLVIILFGFRPLLNEELNLESETVALLSDQQYGLLSTNLSKHREMFVHGLPGSGKTTLALMIVGKIRNVFNCQADNILYICENQSLKRFIVRKNVCQAVTRKTFMKNTFDNVQHIIVDEAQNFRTEDGNWYAKAKAITQRARDGPGVLYIFLDYFQINHLCCSGLPELQHQKPLLKLTRMLRSGDNITSYLQDIMHQIRENPPPNVPQEALMVGEELEWGPDVTGNLEITDNLNLEQMSVYVAEKCQSLWRSGYFTDVAVLFTRARDIEKCRDKLLLAMRRRSMSQLAEEPSLLVQVREGLDSLGSHVVLESVHRFSGMERSIVFGIIPMGSETAIFYNALLCLASRARTHLYIVKVVF","sequence_length":884,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"226f0b674ed9302f4577123323f4ae7b87d701d1cf1c6d26dbd84a25c7a147d2","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q8CBA2.json","taxon_id":"10090","uniprot_accession":"Q8CBA2","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR031450","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR048729","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF21026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/b3r-pf17057.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF17057","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/b3r-pf17057.yaml"}],"pfam_ids":["PF04326","PF17057","PF21026"],"protein_name":"Ribonuclease SLFN12","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIGLNEDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKRLKSLRDQFSFAENLYQIIGIDCFQKNDKKMFKSCRRLT","sequence_length":578,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"ddcee49b9f68888a9f639f9021f2f3475461b114d2ef807dff68d3645eda4e68","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q8IYM2.json","taxon_id":"9606","uniprot_accession":"Q8IYM2","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/t-cell-proliferation-involved-in-immune-response-go0002309.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0002309","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/t-cell-proliferation-involved-in-immune-response-go0002309.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR031450","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007421","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04326","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038461","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.30.950.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml"}],"pfam_ids":["PF04326","PF17057"],"protein_name":"Schlafen family member 2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGTRLEATEQSNHRTQRNDIQLENAKAAGKMGISVDLEAKYAKLGLNLGAITFGEKDRKKMKNSHLRKQENANISLAVCALLNSGGGAIKVKIENENYSLTRDGLGLDLEASLCKCLPFVQWHLDFTESEGYIYIYVKSWSQEIFGLPIGTLRTNLYVRSMSSSVQVSAAAALEFLQDLEETGGRPCVRPELPASIAFPEVEGEWHLEDLAAALFNRTEFQYEETFPFTRSRYVEVTLLSAKRLRKRIKELLPQTVSAFANTDGGFLFIGLDGKTQQIIGFEAEKSDLVLLESEIEKHIRQLPVTHFCEEKEKIKYTCKFIEVHKSGAVCAYVCALRVERFCCAVFAAEPESWHVEGGCVKRFTTEEWVKLQMNAPSG","sequence_length":378,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"be205b0a1e169ce1a7291d6c63c6ad27616b3cb9d5a33b2ed1c0d9a2d5a2c84e","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q9Z0I6.json","taxon_id":"10090","uniprot_accession":"Q9Z0I6","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR031450","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007421","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04326","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038461","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.30.950.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml"}],"pfam_ids":["PF04326","PF17057"],"protein_name":"Schlafen family member 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MNITDEGTPVLILNAGGITLGTESRKTMENHDRVEENRNITKALCALINSGEGKVKAHIKNPDYILSKHGIGEDLETSFKNILPSRPLDFKQYQSYFFICVEKSQSPDVSVGKPATIATNLYMRNGASSVEMNLDAAQKFLDNIKVAGGRSPSARPSDRPGDDTQEEGHIQELAAAFFKQSKLTKKENFLFSESKNVEYKSFETKKLLQRVKEILPRTVSAFANTDGGYLFIGLDEKKQEIVGFEAKNCQPKCLESEIEKCIQQLPVTHFCEEREKIKYKCKFIEVHDSGVVCKYVCALRVERFCCAVFAAEPESWHMKDGGVKRFTIEEWIKLLMS","sequence_length":337,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"9920333549951dd3929bdd425b2b2e9da395b4e9f07c240a9a0aec0668acf046","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q9Z0I7.json","taxon_id":"10090","uniprot_accession":"Q9Z0I7","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/platelet-maturation-go0036345.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0036345","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/platelet-maturation-go0036345.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR031450","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/poxin-schlafen-schlafen-like-n-terminal-domain-ipr031450.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007421","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-alba-2-domain-ipr007421.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR048729","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/schlafen-gtpase-like-domain-ipr048729.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04326","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-alba-2-pf04326.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF21026","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/slfn-gtpase-like-pf21026.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038461","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/schlafen-alba-2-domain-superfamily-ipr038461.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.30.950.30","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/schlafen-aaa-domain-3-30-950-30.yaml"}],"pfam_ids":["PF04326","PF17057","PF21026"],"protein_name":"Protein SLFN14","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MPYAEITVNLGKVTLGEENRKKMTNSCLKRHENSSLVQAVCALLNSGGGVIKAEINDKSYSYRCHGLGQDLETSFQKLLPSGSQKHLDYMQQNHDLLIFVKSWSPDASSLPLRICSLRSNLYQRDVTSAINLCANGALELLREKESRAQRGTPRLHSQDHILNRTIQEEEDIKMCALEFLKKDKLNFKEKLSFTESTHVEFKRFTTKKIVPRIKETLAHYVSAFANTQGGYIIIGVDDKSKEVFGCKKEKVNPDSLKTEIKNCIEKLPTYHFCREKPKVNFTTKILKVYQKEALYGFVCVVQVEPFCCVVFAEDPDSWIMENNIVTRLKVQQWVEMMLDIQSDPSSGFPTINDSAHLMTPALSAPRRPAYLTKVLEHKETLQRHFFSVTQENLQFQPESLCKKLFSDHEGLEDLLKAQTHPCSHGIVIFSRSWAGDIGLMREEKVLCDALLVAVGSPLVLYTILTDPSSTGRADYTQNTALQLKRQLQTLGGYPGKICVIPRVIYLASRGSRPDQPPVYYPRPYTLSSKAEVEDLLQGLVLVSLCSRSVLSDQLGCEFFKQCLEEQANTLSRNLQESRELFIHCLPGTRKTALAIKMVEKIKDVFHCKPKEILFVCENDSLRDFVMQQVTCRAVTRRTFMREEFPKIKHIVMDETENFCSRHGDWYVKAKSTTHPKANGAANEHPHHGILWLFLDPFQVRHADGSGLPVPSAQFPRKMITSEIHCAVEIAKVMKDEMKRMQENPPSMGLPDTLATFQEAPYEEAMRAGALPGVCEIKANLTPEQIANYVAEKCHSLFHEGYLPQDIAILYRRREDRGQYKDVLLKAMARGTTEVAFNSAADVCADGIILDSVEQFSGMVRNIVFGLCPESVHSEGVHKLCFASKAIKHLYLLYGGRTAF","sequence_length":899,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"8ed1ca1cb8cc7857b479f041d95fa2e48249ad8f9b5145ad6c943348b580b0bd","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/V9GXG1.json","taxon_id":"10090","uniprot_accession":"V9GXG1","uniprot_release":"2026_03"}],"pfam_id":"PF04326","short_name":"SLFN_AlbA_2","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}