{"cross_mech":[],"family":{"alphafold_models":3087,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This is a family of bacterial Fe(2+) trafficking proteins.","domain_architectures":8,"interpro_id":"IPR007457","known_evidence_count":null,"matches":4562,"name":"Bacterial Fe(2+) trafficking","partial_evidence_count":null,"pfam_id":"PF04362","proteins":4556,"proteomes":4418,"short_name":"Iron_traffic","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04362","structures":4,"taxa":6189,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF04362.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":3087,"domain_architectures":8,"matches":4562,"proteins":4556,"proteomes":4418,"structures":4,"taxa":6189},"curation_status":"SEEDED","description":"This is a family of bacterial Fe(2+) trafficking proteins.","id":"Pfam:PF04362","interpro_id":"InterPro:IPR007457","name":"Bacterial Fe(2+) trafficking","pfam_id":"PF04362","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Iron_traffic","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04362"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF04362.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"85ba1c0def52378198ffcf6ad6a2fed6bcaa80d234dd1c3d8f94ec99c29f5b57"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/iron-traffic-pf04362.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04362","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/iron-traffic-pf04362.yaml"}],"pfam_ids":["PF04362"],"protein_name":"Probable Fe(2+)-trafficking protein","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSRTVFCQRLKKEGPGLDFQLYPGELGKRIFDNISKEAWTEWQKKQVMLINEKKLNMMNLEHRQLLEKEMVNYLFEAGEVAIDGYTPPSK","sequence_length":90,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"6e90370f2947324f40180cad52110b44199ef5fc3eef926be14b28137f1669f4","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/A0KPN5.json","taxon_id":"380703","uniprot_accession":"A0KPN5","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli O1:K1 / APEC","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/iron-traffic-pf04362.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04362","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/iron-traffic-pf04362.yaml"}],"pfam_ids":["PF04362"],"protein_name":"Probable Fe(2+)-trafficking protein","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK","sequence_length":91,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"6be2313ae4366ce6f248da0a3fddf50d90a626a06227061cb18aef0b7c0f7e15","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/A1AFE8.json","taxon_id":"405955","uniprot_accession":"A1AFE8","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/oxidative-damage-protection-protein-nf003817.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:NF003817","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/oxidative-damage-protection-protein-nf003817.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/iron-traffic-pf04362.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04362","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/iron-traffic-pf04362.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/fe-ii-trafficking-protein-yggx-superfamily-ipr036766.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR036766","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/fe-ii-trafficking-protein-yggx-superfamily-ipr036766.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/fe-ii-trafficking-protein-yggx-1-10-3880-10.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:1.10.3880.10","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/fe-ii-trafficking-protein-yggx-1-10-3880-10.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P0A8P3","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF04362"],"protein_name":"Probable Fe(2+)-trafficking protein","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"6be2313ae4366ce6f248da0a3fddf50d90a626a06227061cb18aef0b7c0f7e15","sequence_version":2,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK","sequence_length":91,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"6be2313ae4366ce6f248da0a3fddf50d90a626a06227061cb18aef0b7c0f7e15","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/P0A8P3.json","taxon_id":"83333","uniprot_accession":"P0A8P3","uniprot_release":"2026_03"}],"pfam_id":"PF04362","short_name":"Iron_traffic","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}