{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF04489","protein_label":"Protein UL31","reviewed":true,"short_name":"DUF570","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf570-pf04489.yaml","source_record_id":"Pfam:PF04489","source_record_label":"Protein of unknown function (DUF570)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10360","taxon_label":"Human cytomegalovirus (strain AD169)","uniprot_accession":"P16848","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF04489","protein_label":"U10 protein","reviewed":true,"short_name":"DUF570","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf570-pf04489.yaml","source_record_id":"Pfam:PF04489","source_record_label":"Protein of unknown function (DUF570)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10370","taxon_label":"Human herpesvirus 6A (strain Uganda-1102)","uniprot_accession":"Q01348","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF04489","protein_label":"Protein UL31","reviewed":true,"short_name":"DUF570","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf570-pf04489.yaml","source_record_id":"Pfam:PF04489","source_record_label":"Protein of unknown function (DUF570)","source_section":"canonical_examples","taxon_id":"NCBITaxon:295027","taxon_label":"Human cytomegalovirus (strain Merlin)","uniprot_accession":"Q6SWA0","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF04489","protein_label":"","reviewed":null,"short_name":"DUF570","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf570-pf04489.yaml","source_record_id":"Pfam:PF04489","source_record_label":"Protein of unknown function (DUF570)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":25,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","description_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":3,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"Protein of unknown function, found in herpesvirus and cytomegalovirus.","domain_architectures":1,"interpro_id":"IPR007578","known_evidence_count":null,"matches":33,"name":"Protein of unknown function (DUF570)","partial_evidence_count":null,"pfam_id":"PF04489","proteins":33,"proteomes":22,"short_name":"DUF570","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04489","structures":0,"taxa":96,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF04489.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":25,"domain_architectures":1,"matches":33,"proteins":33,"proteomes":22,"structures":0,"taxa":96},"curation_status":"SEEDED","description":"Protein of unknown function, found in herpesvirus and cytomegalovirus.","id":"Pfam:PF04489","interpro_id":"InterPro:IPR007578","name":"Protein of unknown function (DUF570)","pfam_id":"PF04489","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF570","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04489"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF04489.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"420fb19493ec2422b68cdd40331a07d943b6d15df455d56ae807ab4df9761739"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Human cytomegalovirus (strain AD169)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf570-pf04489.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04489","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf570-pf04489.yaml"}],"pfam_ids":["PF04489"],"protein_name":"Protein UL31","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGDKPTLVTLLTVAVSSPPPSSPLPLVSFTELLLPPPSVAAAAVAATATSEVGEKTAEQEVAAADPETGNERRENRENEGGETRTTGTTAVKRSHDGIPRQLAERLRLCRHMDPEQDYRLPAQDVVTSWIEALRDADRDNYGRCVRHAKIHRSASHLTAYESYLVSITEQYNTASNVTEKASYVQGCIFLSFPVIYNNTQGCGYKYDWSNVVTPKAAYAELFFLLCSTSESSVVLQPLITKGGLCSSMAVYDEETMRQSQAVQIGFLHTQLVMVPFVPHACPHYAVPFTTPGKPGCGGAPSGVAGLEEAAPFGRVSVTRHGATLLCRVDHLTWISKRVTTYGHKKITRYLAQFRGTMDDDEAALPGEDEAWIASKNVQYEFMGLIFTVNVDSLCVDAEQRQLLGTVATSFCHRVSDKITARNMPRAFSFYLLTSAQRGYDLRFSRNPSLFFSGDALNCPLLNEPNVFSLTVHAPYDIHFGVQPRQTVELDLRYVQITDRCFLVANLPHEDAFYTGLSVWRGGEPLKVTLWTRTRSIVIPQGTPIATLYQITEGDGNVYSYNHHTVFRQMHAAGTTTFFLGDMQLPADNFLTSPHP","sequence_length":595,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"369cf359a6939bf06b21dce41430b61449e7557938969b169437055501cb8f59","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/P16848.json","taxon_id":"10360","uniprot_accession":"P16848","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Human herpesvirus 6A (strain Uganda-1102)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf570-pf04489.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04489","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf570-pf04489.yaml"}],"pfam_ids":["PF04489"],"protein_name":"U10 protein","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MEIVTYKTVSARSPTVTWSSGFGRAIASIQKRNQDNIRKPLRFYTGLLHCLIKQYEHCLVPPNKSIRFDKGKIEVAALILDLGHQVLGRQIHVRQRIYSWTSITLPKLFTPKELYFLIASPEEENIAFNPTITKGGWISGSFSYPVDYRSNFSLTGMSANILMVPFVPYKYPLNYARFISSIDLMILNEQFPEHECGDIQILKQRNYLYLGVIKNLTWKKSVTGTGQTAPHRILKASFIGSWPDTSLPDRVALRFFNNTRFTIHCHEFSINIENLGLVKNKEKVFGTLATVCCEQIPSLLTTENLPKYLIVQFEVVTQIEEPEPLLFSSNPKLYFTGDVLNATIQLQHNPNYYELLVHAPYDIHFYPSRCHIVILPIRYFTKPDKQILISGYQNEGFFETQVMLWAPGTPLHITLRSFSPNLILPQSTPIATLFYVERMTSQNNEQKDVIAKLSENGHFIGNLKLPRENFLHHDAIADSPLASISKDSATPGPETVFSSVSPS","sequence_length":503,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"4d0f3624b00e3195fe214e5472e4fe8c3c467cdf583d40df709331786fa18063","sequence_version":3,"source_url":"https://rest.uniprot.org/uniprotkb/Q01348.json","taxon_id":"10370","uniprot_accession":"Q01348","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Human cytomegalovirus (strain Merlin)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf570-pf04489.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF04489","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf570-pf04489.yaml"}],"pfam_ids":["PF04489"],"protein_name":"Protein UL31","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGDKPTLVTLLTVAVSSPPPSSPLPLVSFTELLLPPPSVAAAAVAATATSEVGEKTAEQEVAAAGPETRNERRENREDEGGETRTTGTTAVKRSHDGIPRQLAERLRLCRHMDPEQDYRLPAQDVVTSWIEALRDADRDNYGRCVRHAKIHRSASHLTAYESYLVSITEQYNTASNVTEKASYVQGCIFLSFPVIYNNTQGCGYKYDWSNVVTPKAAYAELFFLLCSTSESSVVLQPLITKGGLCSSMAVYDEETMRQSQAVQIGFLHTQLVMVPFVPHACPHYAVPFTTPGKPGCGGAPSGVAGLEETAPFGRVSVTRHGATLLCRVDHLTWISKRVTTYGHKKITRYLAQFRGTMDDDEAALPGEDEAWIASKNVQYEFMGLIFTVNVDSLCVDAEQRQLLGTVATSFCHRVSDKITARNMPRAFSFYLLTSAQRGYDLRFSRNPSLFFSGDALNCPLLNEPNVFSLTVHAPYDIHFGVQPRQTVELDLRYVQITDRCFLVANLPHEDAFYTGLSVWRGGEPLKVTLWTRTRSIVIPQGTPIATLYQITEGDGNVYSYNHHTVFRQMHAAGATTFFLGDMQLPADNFLTSPHP","sequence_length":595,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"27f5723f282d9f562dc33996ff1648b51cf018ba16245ad1ab7d9dcc9d5e48cc","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q6SWA0.json","taxon_id":"295027","uniprot_accession":"Q6SWA0","uniprot_release":"2026_03"}],"pfam_id":"PF04489","short_name":"DUF570","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}