{"cross_mech":[],"family":{"alphafold_models":2052,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"Mec-17 is the protein product of one of the 18 genes required for the development and function of the touch receptor neuron for gentle touch. Mec-17 is specifically required for maintaining the differentiation of the touch receptor [[cite:PUB00053857]]. The family shares all the residue-motifs characteristic of Gcn5-related acetyl-transferases, though the exact unction is still unknown [[cite:PUB00044970]].","domain_architectures":22,"interpro_id":"IPR007965","known_evidence_count":null,"matches":2415,"name":"GNAT acetyltransferase, Mec-17","partial_evidence_count":null,"pfam_id":"PF05301","proteins":2356,"proteomes":1155,"short_name":"Acetyltransf_16","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05301","structures":18,"taxa":3938,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF05301.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":2052,"domain_architectures":22,"matches":2415,"proteins":2356,"proteomes":1155,"structures":18,"taxa":3938},"curation_status":"SEEDED","description":"Mec-17 is the protein product of one of the 18 genes required for the development and function of the touch receptor neuron for gentle touch. Mec-17 is specifically required for maintaining the differentiation of the touch receptor [[cite:PUB00053857]]. The family shares all the residue-motifs characteristic of Gcn5-related acetyl-transferases, though the exact unction is still unknown [[cite:PUB00044970]].","id":"Pfam:PF05301","interpro_id":"InterPro:IPR007965","name":"GNAT acetyltransferase, Mec-17","pfam_id":"PF05301","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Acetyltransf_16","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05301"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF05301.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"8484874787f2fbec8751d551c1f4c266be40ad6568de2a121e5faad37e8b14cb"}},"protein_examples":{"candidate_count":8,"discovery_scanned":true,"example_count":8,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Plasmodium falciparum (isolate 3D7)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0019799","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007965","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/profile/gnat-atat.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS51730","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/profile/gnat-atat.yaml"}],"pfam_ids":["PF05301"],"protein_name":"Alpha-tubulin N-acetyltransferase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"METFNHIDIKKYTREDLLYLRNTNNVLFKMFQKQVDEIACLSSKEQKLCGTLTSINNIINENYTIYCLIHTDGLIGFIKIGEKNLYLYDKIKLHYGKCTCVLDFYILEKFQKRGLGIKIFNFMLKDNDISAFCLCYDNPSYKLQNFLKKYFSPCVLIKQPNHFVIFSNYFKNVSIKKVYERISN","sequence_length":184,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"e8098097aa056b6ebc76f2623117c814db52d2e2a04de767934a5342ae3384d6","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/C0H559.json","taxon_id":"36329","uniprot_accession":"C0H559","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Caenorhabditis elegans","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0019799","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/mechanoreceptor-differentiation-go0042490.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0042490","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/mechanoreceptor-differentiation-go0042490.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007965","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/profile/gnat-atat.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS51730","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/profile/gnat-atat.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:O45100","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF05301"],"protein_name":"Alpha-tubulin N-acetyltransferase 1","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"8cb6ffbb9fe8dd1bb3cba01bcc73f4de3838117ed103f0522c556d90eb5ea6cf","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MQVDADLRPILGPQLVRLDPMRVKQLQDPIVYEAIDNLAKLSAHCLQLRTPLTTCEKLINSDSTLYLSWKYDEEEKVSRLMGFAKVGRKKLFLYDSQMQTYEGEILCLLDFYVHFSCQRQGVGQQILDYMFSQEHTEPYQLALDNPSVTLLGFMSQKYGLIKPVWQNTNFVVFEELFLALSAENGIEKPPPDGWRRPMTPRRLGTGMTDTRWLQHAVSGHQSKGNAMAAPVDADMTPQGALSNRAHQAKARKAHILSSKPLW","sequence_length":262,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"8cb6ffbb9fe8dd1bb3cba01bcc73f4de3838117ed103f0522c556d90eb5ea6cf","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/O45100.json","taxon_id":"6239","uniprot_accession":"O45100","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Caenorhabditis elegans","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0019799","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007965","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/profile/gnat-atat.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS51730","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/profile/gnat-atat.yaml"}],"pfam_ids":["PF05301"],"protein_name":"Alpha-tubulin N-acetyltransferase 2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MEIAFDLSTIFTDNIQRLTRTDLLKYGPKRYWAVAQSIDCLGEMSSKFHGWKRVITMYDKIVDHDEEQTTYIMWEKVNGSKSILKGLLRVGYKTLYLTDNEQNQYMEKAMCILDFFVVPTEQRSGNGFKMFDEMLKAENVTVDQCAFDKPSAALQQFLEKYYDRKDLVWQSNKYALCSNFFIGRHPTVPFTPRQTKRASRASSAVSSHASSRNTSPIGRNRPRHDSVADLMRQDMLAGVRAEVDPNSPTGLKNARDFGHRRIW","sequence_length":263,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"33e367641fb7df2103ac752f9fc22cd593336d153dc0097ccee88911b1a1ec3c","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q23192.json","taxon_id":"6239","uniprot_accession":"Q23192","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0019799","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/alpha-tubulin-acetylation-go0071929.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0071929","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/alpha-tubulin-acetylation-go0071929.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/n-acyltransferase-superfamily-various-enzymes-that-characteristically--cd04301.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd04301","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/n-acyltransferase-superfamily-various-enzymes-that-characteristically--cd04301.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007965","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/acetyltransf-16-pf05301.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF05301","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/acetyltransf-16-pf05301.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/profile/gnat-atat.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS51730","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/profile/gnat-atat.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/6-20-370-120-6-20-370-120.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:6.20.370.120","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/6-20-370-120-6-20-370-120.yaml"}],"pfam_ids":["PF05301"],"protein_name":"Alpha-tubulin N-acetyltransferase 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIIDELGKASAKAQNLSAPITSASRMQSNRHVVYILKDSSARPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQRRRTRGTPPGLVAQSCCYSRHGGVNSSSPNTGNQDSKQGEQETKNRSASEEQALSQDGSGEKPMHTAPPQAPAPPAQSWTVGGDILNARFIRNLQERRSTRPW","sequence_length":421,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"e4ac57d3e625cfd4807b85309c05034d6cff5f0136f0b351320dbfdf259a4661","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q5SQI0.json","taxon_id":"9606","uniprot_accession":"Q5SQI0","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Rattus norvegicus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/acetyltransf-16-pf05301.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF05301","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/acetyltransf-16-pf05301.yaml"}],"pfam_ids":["PF05301"],"protein_name":"Alpha-tubulin N-acetyltransferase 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIVDELGKASAKAQHLPAPITSALRMQSNRHVIYVLKDTSARPAGKGAIIGFLKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSPKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHRSPTPSLRATRHSRAAVVDPIPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPDRGPLRPFVPEQELLRSLRLCPPHPTARLLLATDPGGSPAQRRRTRETPWGLVAQSCHYSRHGGFNTSFLGTGNQERKQGEQEAEDRSASEDQVLLQDGSGEEPTHTVAPRAQAPPAQSWMVGGDILNARVIRNLQERRNTRPW","sequence_length":421,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"c0178fe12efa43bfc5e91bf2385d7eedb174495f719575f1bcb76725f82acbd4","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q6MG11.json","taxon_id":"10116","uniprot_accession":"Q6MG11","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/localization/go/microtubule-bundle-go0097427.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0097427","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/localization/go/microtubule-bundle-go0097427.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0019799","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/alpha-tubulin-acetylation-go0071929.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0071929","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/alpha-tubulin-acetylation-go0071929.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/cdd/n-acyltransferase-superfamily-various-enzymes-that-characteristically--cd04301.yaml","qualification_status":"NOT_ASSESSED","record_id":"CDD:cd04301","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/cdd/n-acyltransferase-superfamily-various-enzymes-that-characteristically--cd04301.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007965","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/acetyltransf-16-pf05301.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF05301","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/acetyltransf-16-pf05301.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/profile/gnat-atat.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS51730","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/profile/gnat-atat.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/6-20-370-120-6-20-370-120.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:6.20.370.120","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/6-20-370-120-6-20-370-120.yaml"}],"pfam_ids":["PF05301"],"protein_name":"Alpha-tubulin N-acetyltransferase 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIVDELGKASAKAQHLPAPITSALRMQSNRHVIYILKDTSARPAGKGAIIGFLKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQHMLQKERVEPHQLAIDRPSPKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHRPPTSSLRATRHSRAAVADPIPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPDRGPLRPFVPEQELLRSLRLCPPHPTARLLLATDPGGSPAQRRRTRGTPWGLVAQSCHYSRHGGFNTSFLGTGNQERKQGEQEAEDRSASEDRVLLLDGSGEEPTQTGAPRAQAPPPQSWTVGGDIMNARVIRNLQERRSTRPW","sequence_length":421,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"0deae8c85f0bd681a368df7f0b557a7a185de49974eac7f08204246847d905d2","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q8K341.json","taxon_id":"10090","uniprot_accession":"Q8K341","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Drosophila melanogaster","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0019799","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007965","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/profile/gnat-atat.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS51730","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/profile/gnat-atat.yaml"}],"pfam_ids":["PF05301"],"protein_name":"Alpha-tubulin N-acetyltransferase 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MVEFRFDIKPLFAQPIIKVTSNLLPNTFRGDRRQCLDATSKMTEIIDQLGQLSATSQGLSKPVTTAQRLRMSDNQTIYLLADNEAGHNGAVLGLLKVGTKNLYLFDEAGKTRMVEQTPSILDFYVHESRQRAGLGKRLFQTMLNEEQWTARKCSVDRPSEKLLSFLSKHYGLKRIIPQANNFVLYEGFFNDGESGNGGGNGHANGTPNGLHITNSPNTHLFGATYLGEDSNQRRGSQQQTTPNARLQQITQISPSGRYGAKRPTCSMAEIIHAGNSKGGNGNGSAEANSGNGNHDIPEIAEQLQRQSLADLEANSYEPEPEVEPEPEPEPEPEPEPEVITPPSPPPKSHTPTPPSVRSPEVAESIVGDNRRAPAFQLSKQHTGMKNRSFGVGMAVMPSSKMEFDQMEREDFGVVKINRPPGHEVTSPGQDNTDAMSTVSSGGGGLTDQGYYDLKFYHNKLW","sequence_length":461,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"5a1ca09f744042603a3b9cfe1cc5aca58cc93622b38b9b6e7b4d4043a92d6f1c","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q9VSY4.json","taxon_id":"7227","uniprot_accession":"Q9VSY4","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Drosophila melanogaster","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0019799","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/tubulin-n-acetyltransferase-activity-go0019799.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR007965","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/gcn5-related-n-acetyltransferase-gnat-domain-atat-type-ipr007965.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/profile/gnat-atat.yaml","qualification_status":"NOT_ASSESSED","record_id":"PROSITE:PS51730","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/profile/gnat-atat.yaml"}],"pfam_ids":["PF05301"],"protein_name":"Alpha-tubulin N-acetyltransferase 2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MVEFAFDIKHLFPQSIIRVQAHSLRPKVTQCRRYAQTERGKSTMTSCRLSEILNIMGKLSADAQGLCHAVTSADKLASDQVVYLMADKAAGHWEITGLLKVGTKDLFVFDQGGCYRRLNQTPAILDFYVHESRQRCGQGKLLFEWMLEKQGWSAHKCTVDRPSNKMLAFMAKHYGLVRTIPQGNNFVLYEGFFDDPITTCKSASGLQATGSGCRSRSQGHYVRQEQDQAQIKHGQANRNTVQNDANSGPFRQDQKIVVGTSIYRRRWKSPRTLARAGCREVSGGRRF","sequence_length":287,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"8268f1ea132f5c9594e7f2e160aca68c11c19d768cb58563c830ad8f132133fb","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q9W5X9.json","taxon_id":"7227","uniprot_accession":"Q9W5X9","uniprot_release":"2026_03"}],"pfam_id":"PF05301","short_name":"Acetyltransf_16","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}