{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF05338","protein_label":"Protein ORF30","reviewed":true,"short_name":"DUF717","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf717-pf05338.yaml","source_record_id":"Pfam:PF05338","source_record_label":"Protein of unknown function (DUF717)","source_section":"canonical_examples","taxon_id":"NCBITaxon:868565","taxon_label":"Human herpesvirus 8 type P (isolate GK18)","uniprot_accession":"F5HES7","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF05338","protein_label":"Uncharacterized gene 30 protein","reviewed":true,"short_name":"DUF717","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf717-pf05338.yaml","source_record_id":"Pfam:PF05338","source_record_label":"Protein of unknown function (DUF717)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10383","taxon_label":"Saimiriine herpesvirus 2 (strain 11)","uniprot_accession":"Q01010","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF05338","protein_label":"Uncharacterized gene 30 protein","reviewed":true,"short_name":"DUF717","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf717-pf05338.yaml","source_record_id":"Pfam:PF05338","source_record_label":"Protein of unknown function (DUF717)","source_section":"canonical_examples","taxon_id":"NCBITaxon:82831","taxon_label":"Equine herpesvirus 2 (strain 86/87)","uniprot_accession":"Q66633","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF05338","protein_label":"","reviewed":null,"short_name":"DUF717","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf717-pf05338.yaml","source_record_id":"Pfam:PF05338","source_record_label":"Protein of unknown function (DUF717)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":26,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","description_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":3,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family consists of several herpesvirus proteins of unknown function.","domain_architectures":1,"interpro_id":"IPR008002","known_evidence_count":null,"matches":31,"name":"Protein of unknown function (DUF717)","partial_evidence_count":null,"pfam_id":"PF05338","proteins":31,"proteomes":26,"short_name":"DUF717","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05338","structures":0,"taxa":77,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF05338.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":26,"domain_architectures":1,"matches":31,"proteins":31,"proteomes":26,"structures":0,"taxa":77},"curation_status":"SEEDED","description":"This family consists of several herpesvirus proteins of unknown function.","id":"Pfam:PF05338","interpro_id":"InterPro:IPR008002","name":"Protein of unknown function (DUF717)","pfam_id":"PF05338","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF717","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05338"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF05338.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"4dc608d0982d72c8ce4fe958e608463a555edeefd040580313a088844955de19"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Human herpesvirus 8 type P (isolate GK18)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf717-pf05338.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF05338","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf717-pf05338.yaml"}],"pfam_ids":["PF05338"],"protein_name":"Protein ORF30","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGEPVDPGHVVNEKDFEECEQFFSQPLREQVVAGVRALDGLGLADSLCHKTERLCLLMDLVGTECFARVCRLDTGAK","sequence_length":77,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"780ecccbff192ac772521f96f2d3f00917a001171e9cd9ba973d9a97384a5b24","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/F5HES7.json","taxon_id":"868565","uniprot_accession":"F5HES7","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Saimiriine herpesvirus 2 (strain 11)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf717-pf05338.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF05338","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf717-pf05338.yaml"}],"pfam_ids":["PF05338"],"protein_name":"Uncharacterized gene 30 protein","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSKPCISEEDFKDCQAFFAKPLPILVAEISKSLANIDFVDTASQQVDQLGIFLDLIGTECFKEVLCPHTSANLTN","sequence_length":75,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"faa34bff5c7f37528dbe74d79de1e882f60335d074f27baa91093bf796f320b8","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q01010.json","taxon_id":"10383","uniprot_accession":"Q01010","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Equine herpesvirus 2 (strain 86/87)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf717-pf05338.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF05338","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf717-pf05338.yaml"}],"pfam_ids":["PF05338"],"protein_name":"Uncharacterized gene 30 protein","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSLVESDFEECLEFFSRPLPELLDGLLASLGEAGNLDSQGQRVEKAALVLELTGTECVREVVFKQEERGRLRGTEGPSRPPSSGAGDPRGATTLG","sequence_length":95,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"c5047e1f8bf539e046be073c8c2db8c3028114f1fba82afb8fa8830354414ba8","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q66633.json","taxon_id":"82831","uniprot_accession":"Q66633","uniprot_release":"2026_03"}],"pfam_id":"PF05338","short_name":"DUF717","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}