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They were identified as proteins involved in vacuolar processing and morphology [[cite:PUB00066964]] and meiosis [[cite:PUB00044889]], respectively.","domain_architectures":54,"interpro_id":"IPR008506","known_evidence_count":null,"matches":3893,"name":"SRP-independent targeting protein 2/TMEM208","partial_evidence_count":null,"pfam_id":"PF05620","proteins":3823,"proteomes":3211,"short_name":"TMEM208_SND2","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05620","structures":0,"taxa":8600,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF05620.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":3288,"domain_architectures":54,"matches":3893,"proteins":3823,"proteomes":3211,"structures":0,"taxa":8600},"curation_status":"SEEDED","description":"This family includes SRP-independent targeting protein 2 (SND2) from yeast and transmembrane protein 208 (TMEM208) from mammals. 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