{"cross_mech":[],"family":{"alphafold_models":1401,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"YjbH is a family of Gram-negative beta-barrel outer-membrane lipoproteins that act as putative porins. YbjH is one of four gene-products expressed from an operon, yjbEFGH, which is regulated by the Rcs phosphorelay in a RcsA-dependent manner, similar to that of other exopolysaccharide biosynthetic pathways. It is highly possible that the yjbEFGH operon encodes a system involved in EPS secretion since none of the products is predicted to have enzymic activity, the products are all secreted and YbjH and F are predicted to be beta-barrel lipoproteins similar to porins. It may be that the operon products play some role in biofilm formation and/or matrix production [[cite:PUB00058168]].","domain_architectures":11,"interpro_id":"IPR010344","known_evidence_count":null,"matches":2441,"name":"Exopolysaccharide biosynthesis protein YbjH","partial_evidence_count":null,"pfam_id":"PF06082","proteins":2228,"proteomes":1876,"short_name":"YjbH","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06082","structures":0,"taxa":2865,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF06082.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":1401,"domain_architectures":11,"matches":2441,"proteins":2228,"proteomes":1876,"structures":0,"taxa":2865},"curation_status":"SEEDED","description":"YjbH is a family of Gram-negative beta-barrel outer-membrane lipoproteins that act as putative porins. YbjH is one of four gene-products expressed from an operon, yjbEFGH, which is regulated by the Rcs phosphorelay in a RcsA-dependent manner, similar to that of other exopolysaccharide biosynthetic pathways. It is highly possible that the yjbEFGH operon encodes a system involved in EPS secretion since none of the products is predicted to have enzymic activity, the products are all secreted and YbjH and F are predicted to be beta-barrel lipoproteins similar to porins. It may be that the operon products play some role in biofilm formation and/or matrix production [[cite:PUB00058168]].","id":"Pfam:PF06082","interpro_id":"InterPro:IPR010344","name":"Exopolysaccharide biosynthesis protein YbjH","pfam_id":"PF06082","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"YjbH","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06082"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF06082.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"9f0ffa26388f35a5331af991f652832dfe8b00a34e132c8494187c09902a15c6"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/yjbh-pf06082.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF06082","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/yjbh-pf06082.yaml"}],"pfam_ids":["PF06082"],"protein_name":"Uncharacterized lipoprotein YjbH","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MKKRHLLSLLALGISTACYGETYPAPIGPSQSDFGGVGLLQTPTARMAREGELSLNYRDNDQYRYYSASVQLFPWLETTLRYTDVRTRQYSSVEAFSGDQTYKDKAFDLKLRLWEESYWLPQVAVGARDIGGTGLFDAEYLVASKAWGPFDFTLGLGWGYLGTSGNVKNPLCSASDKYCYRDNSYKQAGSIDGSQMFHGPASLFGGVEYQTPWQPLRLKLEYEGNNYQQDFAGKLEQKSKFNVGAIYRVTDWADVNLSYERGNTFMFGVTLRTNFNDLRPSYNDNARPQYQPQPQDAILQHSVVANQLTLLKYNAGLADPQIQAKGDTLYVTGEQVKYRDSREGIIRANRIVMNDLPDGIKTIRITENRLNMPQVTTETDVASLKNHLAGEPLGHETTLAQKRVEPVVPQSTEQGWYIDKSRFDFHIDPVLNQSVGGPENFYMYQLGVMGTADLWLTDHLLTTGSLFANLANNYDKFNYTNPPQDSHLPRVRTHVREYVQNDVYVNNLQANYFQHLGNGFYGQVYGGYLETMFGGAGAEVLYRPLDSNWAFGLDANYVKQRDWRSAKDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVVGGYATITNVSKEEYGEGDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGRKFQLYDMTSDRSVNFR","sequence_length":698,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"7d253f3e04efb08f47227e85529bb214c1513f37efd7fb8e0e71fab488e8a292","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P32689.json","taxon_id":"83333","uniprot_accession":"P32689","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/yjbh-pf06082.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF06082","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/yjbh-pf06082.yaml"}],"pfam_ids":["PF06082"],"protein_name":"Uncharacterized lipoprotein GfcD","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MKKNSYLLSCLAIAVSSACHAEVLTYPDPLGSSQSDFGGTGLLQMPNARIAPEGEFSVNYRDNDQYRFYSTSVALFPWLEGTIRYTDVRTRKYSQWEDFSGDQSYKDKSFDFKLRLWEEGYWLPQVAFGKRDIAGTGLFDGEYLVASKQAGPFDFTLGMAWGYAGNAGNITNPFCRVSDKYCHRAESHDAGDISFSDIFRGPASIFGGIEYQTPWNPLRLKLEYDGNNYQNDFAGKLPQASHFNVGAVYRAASWADLNLSYERGNTLMFGFTLRTNFNDLRPALRDTPKPAYQPAPESEGLQYTTVANQLTALKYNAGFDAPEIQLRDKTLYMSGQQYKYRDSREAVDRANRILVNNLPQGVEKISVTQKREHMAMVTTETDVASLRKQLAGTAPGQSEPLQQQRVEAEDLSAFGRGYRIREDRFSYSFNPTLSQSLGGPEDFYMFQLGLMSSARYWFTDHLLLDGGIFTNIYNNYDKFKSSLLPADSTLPRVRTHIRDYVRNDVYLNNLQANYFADLGNGFYGQVYGGYLETMYAGVGSELLYRPLDACWALGVDVNYVKQRDWDNMMRFTDYSTPTGFVTAYWNPPTLNGVLMKLSVGQYLAKDKGATIDVAKRFDSGVAVGVWAAISNVSKDDYGEGGFSKGFYISIPFDLMTIGPNRNRAVVSWTPLTRDGGQMLSRKYQLYPMTAEREVPVGQ","sequence_length":698,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"fa0d97767d5ee05f00c51c874294abda7e42cbb1c632011dcb89cd73e98212ec","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P75882.json","taxon_id":"83333","uniprot_accession":"P75882","uniprot_release":"2026_03"}],"pfam_id":"PF06082","short_name":"YjbH","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}