{"cross_mech":[],"family":{"alphafold_models":1935,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents the catalytic C-terminal domain of the LpxI enzyme that is involved in biosynthesis of lipid A. Specifically it carried out the hydrolysis of UDP-2,3-diacyl- glucosamine. This step is either carried out by LpxI or LpxH [[cite:PUB00091500]]. This domain comprises a five-stranded mixed beta-sheet bracketed by one alpha-helix on one side and three on the other. This domain is structurally related to a superfamily that includes cytosine deaminase [[cite:PUB00091500]].","domain_architectures":7,"interpro_id":"IPR010415","known_evidence_count":null,"matches":2774,"name":"LpxI C-terminal domain","partial_evidence_count":null,"pfam_id":"PF06230","proteins":2749,"proteomes":2742,"short_name":"LpxI_C","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06230","structures":2,"taxa":4373,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF06230.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":1935,"domain_architectures":7,"matches":2774,"proteins":2749,"proteomes":2742,"structures":2,"taxa":4373},"curation_status":"SEEDED","description":"This entry represents the catalytic C-terminal domain of the LpxI enzyme that is involved in biosynthesis of lipid A. Specifically it carried out the hydrolysis of UDP-2,3-diacyl- glucosamine. This step is either carried out by LpxI or LpxH [[cite:PUB00091500]]. This domain comprises a five-stranded mixed beta-sheet bracketed by one alpha-helix on one side and three on the other. This domain is structurally related to a superfamily that includes cytosine deaminase [[cite:PUB00091500]].","id":"Pfam:PF06230","interpro_id":"InterPro:IPR010415","name":"LpxI C-terminal domain","pfam_id":"PF06230","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"LpxI_C","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06230"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF06230.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"4a2859112b54f0084fde932e772bbf42ffdd51780ec3d384b6e345781af8fd0b"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF06230","short_name":"LpxI_C","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}
