{"cross_mech":[],"family":{"alphafold_models":3614,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"Fn3_5 is an fn3-like domain which is frequently found as the first of three on streptococcal C5a peptidase (SCP), a highly specific protease and adhesin/invasin. 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proteinase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MQRKKKGLSILLAGTVALGALAVLPVGEIQAKAAISQQTKVSSLANTVKAATAKQAATDTTAATTNQAIATQLAAKGIDYNKLNKVQQQDTYVDVIVQMSAAPASENGTLRTDYSSTAEIQQETNKVIAAQASVKAAVEQVTQQTAGESYGYVVNGFSTKVRVVDIPKLKQIAGVKTVTLAKVYYPTDAKANSMANVQAVWSNYKYKGEGTVVSVIDTGIDPTHKDMRLSDDKDVKLTKYDVEKFTDTAKHGRYFTSKVPYGFNYADNNDTITDDTVDEQHGMHVAGIIGANGTGDDPTKSVVGVAPEAQLLAMKVFTNSDTSATTGSATLVSAIEDSAKIGADVLNMSLGSDSGNQTLEDPEIAAVQNANESGTAAVISAGNSGTSGSATQGVNKDYYGLQDNEMVGTPGTSRGATTVASAENTDVISQAVTITDGKDLQLGPETIQLSSNDFTGSFDQKKFYVVKDASGDLSKGAAADYTADAKGKIAIVKRGELNFADKQKYAQAAGAAGLIIVNNDGTATPLTSIRLTTTFPTFGLSSKTGQKLVDWVTAHPDDSLGVKIALTLLPNQKYTEDKMSDFTSYGPVSNLSFKPDITAPGGNIWSTQNNNGYTNMSGTSMASPFIAGSQALLKQALNNKNNPFYADYKQLKGTALTDFLKTVEMNTAQPINDINYNNVIVSPRRQGAGLVDVKAAIDALEKNPSTVVAENGYPAVELKDFTSTDKTFKLTFTNRTTHELTYQMDSNTDTNAVYTSATDPNSGVLYDKKIDGAAIKAGSDITVPAGKTAQIEFTLSLPKSFDQQQFVEGFLNFKGSDGSRLNLPYMGFFGDWNDGKIVDSLNGITYSPAGGNYGTVPLLTNKNTGHQYYGGMVTDADGKQTVDDQAIAFSSDKNALYNDISMQYYLLRNISNVQVDILDGQGNKVTTLSSSTNQTKTYYDAHSQKYIYYNAPAWDGTYYDQRDGNIKTADDGSYTYRISGVPEGGDKRQVFDVPFKLDSKAPTVRHVALSAKTENGKTQYYLTAEAKDDLSGLDATKSVKTAINEVTNLDATFTDAGTTADGYTKIETPLSDEQAQALGNGDNSAELYLTDNASNATNQDASVQKPGSTSFDLIVNGGGIPDKISSTTTGYEANTQGGGTYTFSGTYPAAVDGTYTDAQGKKHDLNTTYDAATNSFTASMAVTNADYAAQVDLYADKAHTQLLKHFDTKVRLTAPTFTDLKFNNGSDQTSEATIKVTGTVSSDTKTVNVGDTVAALDAQHHFSVDVPVNYGDNTIKVTATDEDGNTTTEQKTITSSYDPDVLKNAVTFDQGVKFGANEFNATSAKFYDPKTGIATITGKVKHPTTTLQVDGKQISIKNDLTFSFTLDLGTLGQKPFGVVVGDTTQNKTFQEALTFILDAVAPTLSLDSSTDAPVYTNDPNFQITGTATDNAQYLSLAINGSHVASQYADININSGKPGHMAIDQPVKLLEGKNVLTVAVTDSENNTTTKKITVYYEPKKTLAAPTVTPSTTEPAKTVTLTANAAATGETVQYSADGGKTYQDVPAAGVTVTANGTFKFKSTDLYGNESPAVDYVVTNIKADDPAQLQTAKQALTNLIASAKTLSASGKYDDATTTALAAATQKAQTALDQTDASVDSLTGANRDLQTAINQLAAKLPADKKTSLLNQLQSVKAALGTDLGNQTDPSTGKTFTAALDDLVAQAQAGTQTADQLQASLAKVLDAVLAKLAEGIKAATPAEVGNAKDAATGKTWYADIADTLTSGQASADASDKLAHLQALQSLKTKVAAAVEAAKTAGKGDDTTGTSDKGGGQGTPAPAPGDTGKDKGDEGSQPSSGGNIPTKPATTTSTSTDDTTDRNGQHTSGKGALPKTAETTERPAFGFLGVIVVSLMGVLGLKRKQREE","sequence_length":1902,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"9f9c9b7ce9c9e0bdecb67e6c3cd656eaea761ac66f50379eece2c5964b5a39a1","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q02470.json","taxon_id":"1597","uniprot_accession":"Q02470","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Streptococcus pyogenes serotype M18 (strain MGAS8232)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/chu-c-pf13585.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF13585","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/chu-c-pf13585.yaml"}],"pfam_ids":["PF00082","PF02225","PF06280","PF13585","PF22143"],"protein_name":"C5a peptidase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPAAEQAVETPQPTAVSEEVPSSKETKTPQTPDNAEETVADKANDLALQAPAKTADTPATSKATIRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKENPQKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYEIQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYYQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMKNGYFLEGFVRFKQDPKKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTLEVATSATFSTEDRRLTLASKPKTSQPIYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQAPDKKPEAKPEQDGSGQTPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASARDQLPTTNDKDTNRLHLLKLVMTTFFFGLVAHIFKTKRQKETKK","sequence_length":1150,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"539ec61743cba9777c2cee02d1e00d6c7b5f7c0ffad11dde03f049808179cdb6","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q8NZ80.json","taxon_id":"186103","uniprot_accession":"Q8NZ80","uniprot_release":"2026_03"}],"pfam_id":"PF06280","short_name":"fn3_5","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}