{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF07118","protein_label":"Uncharacterized protein ORF99","reviewed":true,"short_name":"DUF1374","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf1374-pf07118.yaml","source_record_id":"Pfam:PF07118","source_record_label":"Protein of unknown function (DUF1374)","source_section":"canonical_examples","taxon_id":"NCBITaxon:654909","taxon_label":"Acidianus filamentous virus 1 (isolate United States/Yellowstone)","uniprot_accession":"Q70LE8","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF07118","protein_label":"Uncharacterized protein 75","reviewed":true,"short_name":"DUF1374","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf1374-pf07118.yaml","source_record_id":"Pfam:PF07118","source_record_label":"Protein of unknown function (DUF1374)","source_section":"canonical_examples","taxon_id":"NCBITaxon:157898","taxon_label":"Sulfolobus islandicus rod-shaped virus 1","uniprot_accession":"Q8QL13","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF07118","protein_label":"Uncharacterized protein 102","reviewed":true,"short_name":"DUF1374","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf1374-pf07118.yaml","source_record_id":"Pfam:PF07118","source_record_label":"Protein of unknown function (DUF1374)","source_section":"canonical_examples","taxon_id":"NCBITaxon:157898","taxon_label":"Sulfolobus islandicus rod-shaped virus 1","uniprot_accession":"Q8QL51","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF07118","protein_label":"","reviewed":null,"short_name":"DUF1374","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf1374-pf07118.yaml","source_record_id":"Pfam:PF07118","source_record_label":"Protein of unknown function (DUF1374)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":8,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","description_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":3,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family consists of several hypothetical Sulfolobus virus proteins of around 100 residues in length. The function of this family is unknown.","domain_architectures":2,"interpro_id":"IPR009804","known_evidence_count":null,"matches":40,"name":"Protein of unknown function (DUF1374)","partial_evidence_count":null,"pfam_id":"PF07118","proteins":40,"proteomes":13,"short_name":"DUF1374","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07118","structures":5,"taxa":89,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF07118.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":8,"domain_architectures":2,"matches":40,"proteins":40,"proteomes":13,"structures":5,"taxa":89},"curation_status":"SEEDED","description":"This family consists of several hypothetical Sulfolobus virus proteins of around 100 residues in length. The function of this family is unknown.","id":"Pfam:PF07118","interpro_id":"InterPro:IPR009804","name":"Protein of unknown function (DUF1374)","pfam_id":"PF07118","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF1374","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07118"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF07118.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"beed6654eff6a534e1dd2f040f81f9e61e41c70fff5af9e0bb623b58a2d79e01"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Acidianus filamentous virus 1 (isolate United States/Yellowstone)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf1374-pf07118.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF07118","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf1374-pf07118.yaml"}],"pfam_ids":["PF07118"],"protein_name":"Uncharacterized protein ORF99","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MDTHEFHKLLIKVVDLFLEDRIKEFELKLNTTLDELEFEELIGKPDSSNSAENNGIFIDEYSYDASENAIKKLFVEYVRQPEFKYTVLSIKGVNDWVRE","sequence_length":99,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"c50f087967e1042a3c3e66dd13dc61af845123582c1f3a83e6e01d98dd3b39df","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q70LE8.json","taxon_id":"654909","uniprot_accession":"Q70LE8","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Sulfolobus islandicus rod-shaped virus 1","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf1374-pf07118.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF07118","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf1374-pf07118.yaml"}],"pfam_ids":["PF07118"],"protein_name":"Uncharacterized protein 75","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MDLFFEDSIIQELSLKFKISFEINEEEYQQLIELAFSQFIYPSNDNIEIKINTKELADNEKALLYEIQLWRTKKS","sequence_length":75,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"a32c484cb46172c0cddbce073d914fcea5528b87eab997d54dec0d79dcf5dae8","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q8QL13.json","taxon_id":"157898","uniprot_accession":"Q8QL13","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Sulfolobus islandicus rod-shaped virus 1","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf1374-pf07118.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF07118","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf1374-pf07118.yaml"}],"pfam_ids":["PF07118"],"protein_name":"Uncharacterized protein 102","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MEFEDLDVVLYVFFENPEMKSFEFEFKQLFETTESGLRYLIGVPDSRNKIKNNNEIIEEFIYYQNDDIVTKLIFYYTKGTNRIYIRKIYGWKEKRLESEDEE","sequence_length":102,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"4f511b59b861fbd522218043207a4836399877d7b46c1c5c0db65bc810062410","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q8QL51.json","taxon_id":"157898","uniprot_accession":"Q8QL51","uniprot_release":"2026_03"}],"pfam_id":"PF07118","short_name":"DUF1374","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}