{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF07369","protein_label":"Uncharacterized protein YrdB","reviewed":true,"short_name":"DUF1488","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf1488-pf07369.yaml","source_record_id":"Pfam:PF07369","source_record_label":"Protein of unknown function (DUF1488)","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P45795","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF07369","protein_label":"Uncharacterized protein YrdB","reviewed":true,"short_name":"DUF1488","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf1488-pf07369.yaml","source_record_id":"Pfam:PF07369","source_record_label":"Protein of unknown function (DUF1488)","source_section":"canonical_examples","taxon_id":"NCBITaxon:623","taxon_label":"Shigella flexneri","uniprot_accession":"Q83JD2","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF07369","protein_label":"","reviewed":null,"short_name":"DUF1488","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf1488-pf07369.yaml","source_record_id":"Pfam:PF07369","source_record_label":"Protein of unknown function (DUF1488)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF07369","protein_label":"Uncharacterized protein YrdB","reviewed":true,"short_name":"DUF1488","source_category":"sequence/homologous_superfamily/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/homologous_superfamily/interpro/shew3726-like-superfamily-ipr036692.yaml","source_record_id":"InterPro:IPR036692","source_record_label":"Shew3726-like superfamily","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P45795","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF07369","protein_label":"Uncharacterized protein YrdB","reviewed":true,"short_name":"DUF1488","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/shew3726-like-3-30-160-140.yaml","source_record_id":"CATH:3.30.160.140","source_record_label":"Shew3726-like","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P45795","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":1913,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","description_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":2,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":3},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family consists of several hypothetical bacterial proteins of around 85 residues in length. The function of this family is unknown.","domain_architectures":7,"interpro_id":"IPR009962","known_evidence_count":null,"matches":2978,"name":"Protein of unknown function (DUF1488)","partial_evidence_count":null,"pfam_id":"PF07369","proteins":2977,"proteomes":1716,"short_name":"DUF1488","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07369","structures":1,"taxa":2276,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF07369.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":1913,"domain_architectures":7,"matches":2978,"proteins":2977,"proteomes":1716,"structures":1,"taxa":2276},"curation_status":"SEEDED","description":"This family consists of several hypothetical bacterial proteins of around 85 residues in length. The function of this family is unknown.","id":"Pfam:PF07369","interpro_id":"InterPro:IPR009962","name":"Protein of unknown function (DUF1488)","pfam_id":"PF07369","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF1488","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07369"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF07369.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"aad2e442b3c827285d081e6752803d9f73ecf2f115fafe517171eba0eadc60a5"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf1488-pf07369.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF07369","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf1488-pf07369.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/shew3726-like-superfamily-ipr036692.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR036692","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/shew3726-like-superfamily-ipr036692.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/shew3726-like-3-30-160-140.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.30.160.140","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/shew3726-like-3-30-160-140.yaml"}],"pfam_ids":["PF07369"],"protein_name":"Uncharacterized protein YrdB","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MNQAIQFPDREEWDENKKCVCFPALVNGMQLTCAISGESLAYRFTGDTPEQWLASFRQHRWDLEEEAENLIQEQSEDDQGWVWLP","sequence_length":85,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"d4494995681139d23f80e30d125fe39af65427eaf5573486cb584aa5d28a5f69","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P45795.json","taxon_id":"83333","uniprot_accession":"P45795","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Shigella flexneri","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf1488-pf07369.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF07369","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf1488-pf07369.yaml"}],"pfam_ids":["PF07369"],"protein_name":"Uncharacterized protein YrdB","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MNQAIQFPDREEWDENKKCVCFPALVNGMQLTCAISGESLAYRFTGDTPEQWLASFRQHRWDLEEEADNLIQEQSEDDQGWVWLP","sequence_length":85,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"fb74c23e55e9b2a3e155bc8ad7c85ec4f52ad38ac8c8c9f7346b2fa9b10ec7cf","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q83JD2.json","taxon_id":"623","uniprot_accession":"Q83JD2","uniprot_release":"2026_03"}],"pfam_id":"PF07369","short_name":"DUF1488","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}