{"cross_mech":[],"family":{"alphafold_models":5610,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry includes coiled-coil domain-containing proteins 90 (CCDC90) and related proteins. CCDC90A is a key regulator of the mitochondrial calcium uniporter (MCU) and hence was renamed MCUR1 [[cite:PUB00097799],[cite:PUB00076354],[cite:PUB00097801]]. A study in mammals and in yeast homologue fmp32 has reported that MCUR1 is a cytochrome c oxidase assembly factor and that it has an indirect role as a regulator of MCU [[cite:PUB00075452]], however, subsequent publications confirmed the function of MCUR1 as a regulator of MCU [[cite:PUB00097799],[cite:PUB00097800]]. The role of CCDC90B proteins is still not known.","domain_architectures":96,"interpro_id":"IPR024461","known_evidence_count":null,"matches":6782,"name":"Coiled-coil domain-containing protein 90-like","partial_evidence_count":null,"pfam_id":"PF07798","proteins":6646,"proteomes":2866,"short_name":"CCDC90-like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07798","structures":1,"taxa":7214,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF07798.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":5610,"domain_architectures":96,"matches":6782,"proteins":6646,"proteomes":2866,"structures":1,"taxa":7214},"curation_status":"SEEDED","description":"This entry includes coiled-coil domain-containing proteins 90 (CCDC90) and related proteins. CCDC90A is a key regulator of the mitochondrial calcium uniporter (MCU) and hence was renamed MCUR1 [[cite:PUB00097799],[cite:PUB00076354],[cite:PUB00097801]]. A study in mammals and in yeast homologue fmp32 has reported that MCUR1 is a cytochrome c oxidase assembly factor and that it has an indirect role as a regulator of MCU [[cite:PUB00075452]], however, subsequent publications confirmed the function of MCUR1 as a regulator of MCU [[cite:PUB00097799],[cite:PUB00097800]]. The role of CCDC90B proteins is still not known.","id":"Pfam:PF07798","interpro_id":"InterPro:IPR024461","name":"Coiled-coil domain-containing protein 90-like","pfam_id":"PF07798","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"CCDC90-like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07798"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF07798.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"6ad8649da6625e37868bde2c0da49f9f0fff5ad44160962033475a0f61c72093"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo 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