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This domain folds into an (alpha /alpha)6 barrel. Beta-AFase has been characterised as an unusual beta-L-arabinofuranosidase enzyme, [ec:3.2.1.185]. It releases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration [[cite:PUB00075450],[cite:PUB00151606]].","id":"Pfam:PF07944","interpro_id":"InterPro:IPR012878","name":"Beta-L-arabinofuranosidase, GH127 catalytic domain","pfam_id":"PF07944","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Beta-AFase-like_GH127_cat","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF07944"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF07944.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"5547da19e514ef38b7ae756b0e4c076cba80816017c9acd6aa7752ad49eceb24"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/glyco-hydro127c-pf20737.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF20737","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/glyco-hydro127c-pf20737.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/glyco-hydro127m-pf20736.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF20736","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/glyco-hydro127m-pf20736.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/repeat/pfam/beta-afase-like-gh127-cat-pf07944.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF07944","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/repeat/pfam/beta-afase-like-gh127-cat-pf07944.yaml"}],"pfam_ids":["PF07944","PF20736","PF20737"],"protein_name":"Non-reducing end beta-L-arabinofuranosidase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MNVTITSPFWKRRRDQIVESVIPYQWGVMNDEIDTTVPDDPAGNQLADSKSHAVANLKVAAGELDDEFHGMVFQDSDVYKWLEEAAYALAYHPDPELKALCDRTVDLIARAQQSDGYLDTPYQIKSGVWADRPRFSLIQQSHEMYVMGHYIEAAVAYHQVTGNEQALEVAKKMADCLDANFGPEEGKIHGADGHPEIELALAKLYEETGEKRYLTLSQYLIDVRGQDPQFYAKQLKAMNGDNIFHDLGFYKPTYFQAAEPVRDQQTADGHAVRVGYLCTGVAHVGRLLGDQGLIDTAKRFWKNIVTRRMYVTGAIGSTHVGESFTYDYDLPNDTMYGETCASVAMSMFAQQMLDLEPKGEYADVLEKELFNGSIAGISLDGKQYYYVNALETTPDGLDNPDRHHVLSHRVDWFGCACCPANIARLIASVDRYIYTERDGGKTVLSHQFIANTAEFASGLTVEQRSNFPWDGHVEYTVSLPASATDSSVRFGLRIPGWSRGSYTLTVNGKPAVGSLEDGFVYLVVNAGDTLEIALELDMSVKFVRANSRVRSDAGQVAVMRGPLVYCAEQVDNPGDLWNYRLADGVTGADAAVAFQADLLGGVDTVDLPAVREHADEDDAPLYVDADEPRAGEPATLRLVPYYSWANREIGEMRVFQRR","sequence_length":658,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"b7a7f41d8ed3004f8ac5d53da5c7a88917db51ea5d56d5614db2ff383433df7a","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/E8MGH8.json","taxon_id":"565042","uniprot_accession":"E8MGH8","uniprot_release":"2026_03"}],"pfam_id":"PF07944","short_name":"Beta-AFase-like_GH127_cat","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}