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AflB is part of the gene cluster that mediates the biosynthesis of aflatoxins [[cite:PUB00083132]].","domain_architectures":233,"interpro_id":"IPR013565","known_evidence_count":null,"matches":3333,"name":"Fatty acid synthase subunit beta/Fas1-like, helical","partial_evidence_count":null,"pfam_id":"PF08354","proteins":3260,"proteomes":2302,"short_name":"Fas1-AflB-like_hel","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08354","structures":45,"taxa":4165,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF08354.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":205,"domain_architectures":233,"matches":3333,"proteins":3260,"proteomes":2302,"structures":45,"taxa":4165},"curation_status":"SEEDED","description":"This domain has been identified in fungi and bacteria. 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AflB is part of the gene cluster that mediates the biosynthesis of aflatoxins [[cite:PUB00083132]].","id":"Pfam:PF08354","interpro_id":"InterPro:IPR013565","name":"Fatty acid synthase subunit beta/Fas1-like, 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40)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/fas-meander-pf17951.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF17951","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/fas-meander-pf17951.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/fas1-aflb-like-hel-pf08354.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF08354","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/fas1-aflb-like-hel-pf08354.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/fas1-dh-region-pf13452.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF13452","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/fas1-dh-region-pf13452.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/fas1-thioest-ins-pf22235.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF22235","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/fas1-thioest-ins-pf22235.yaml"}],"pfam_ids":["PF00698","PF01575","PF08354","PF13452","PF16073","PF17951","PF22235"],"protein_name":"Fatty 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