{"cross_mech":[],"family":{"alphafold_models":4276,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This is the ssDNA binding domain of anti-restriction factor ArdC deployed by plasmids and phages in polyvalent proteins related to the BHD domains of XPC/Rad4 and the Tc-38 domain found in kinetoplastid minicircle binding proteins [[cite:PUB00098071],[cite:PUB00091133],[cite:PUB00098072]]. The structure of this domain is composed of three alpha-helices and a three-stranded beta-sheet that supports a long and protuberant beta-hairpin [[cite:PUB00098072]]. This domain is also found in the N-terminal region of the RP4 TraC1 primase [[cite:PUB00043496]], together with the Toprim domain (pfam:PF01751, pfam:PF13362 and pfam:PF13662).","domain_architectures":194,"interpro_id":"IPR013610","known_evidence_count":null,"matches":6494,"name":"N-terminal domain of anti-restriction factor ArdC","partial_evidence_count":null,"pfam_id":"PF08401","proteins":6492,"proteomes":4027,"short_name":"ArdcN","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08401","structures":2,"taxa":6807,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF08401.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":4276,"domain_architectures":194,"matches":6494,"proteins":6492,"proteomes":4027,"structures":2,"taxa":6807},"curation_status":"SEEDED","description":"This is the ssDNA binding domain of anti-restriction factor ArdC deployed by plasmids and phages in polyvalent proteins related to the BHD domains of XPC/Rad4 and the Tc-38 domain found in kinetoplastid minicircle binding proteins [[cite:PUB00098071],[cite:PUB00091133],[cite:PUB00098072]]. The structure of this domain is composed of three alpha-helices and a three-stranded beta-sheet that supports a long and protuberant beta-hairpin [[cite:PUB00098072]]. This domain is also found in the N-terminal region of the RP4 TraC1 primase [[cite:PUB00043496]], together with the Toprim domain (pfam:PF01751, pfam:PF13362 and pfam:PF13662).","id":"Pfam:PF08401","interpro_id":"InterPro:IPR013610","name":"N-terminal domain of anti-restriction factor ArdC","pfam_id":"PF08401","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"ArdcN","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08401"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF08401.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"a9722910426d8e4fc6b20644978d3e11da8d170305bc706855de0abe684ac5a8"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia 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primase 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primase 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