{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF08866","protein_label":"","reviewed":null,"short_name":"DUF1831","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf1831-pf08866.yaml","source_record_id":"Pfam:PF08866","source_record_label":"Putative amino acid metabolism","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"KNOWN_HISTORICAL_DUF"}],"family":{"alphafold_models":483,"candidate_reasons":["short_name_matches_duf"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":true,"records_by_mech":{},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.","domain_architectures":1,"interpro_id":"IPR014965","known_evidence_count":null,"matches":699,"name":"Putative amino acid metabolism","partial_evidence_count":null,"pfam_id":"PF08866","proteins":699,"proteomes":699,"short_name":"DUF1831","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08866","structures":1,"taxa":999,"unknown_status":"KNOWN_HISTORICAL_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF08866.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":483,"domain_architectures":1,"matches":699,"proteins":699,"proteomes":699,"structures":1,"taxa":999},"curation_status":"SEEDED","description":"Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.","id":"Pfam:PF08866","interpro_id":"InterPro:IPR014965","name":"Putative amino acid metabolism","pfam_id":"PF08866","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"KNOWN_HISTORICAL_DUF","short_name":"DUF1831","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF08866"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF08866.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"3633ff4e2fa6b3dc1786fab0314bd92dda8b414c9431f4d593a99a41f16190be"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF08866","short_name":"DUF1831","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}
