{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF09185","protein_label":"Uncharacterized protein MG027","reviewed":true,"short_name":"DUF1948","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf1948-pf09185.yaml","source_record_id":"Pfam:PF09185","source_record_label":"Domain of unknown function (DUF1948)","source_section":"canonical_examples","taxon_id":"NCBITaxon:243273","taxon_label":"Mycoplasmoides genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)","uniprot_accession":"P47273","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF09185","protein_label":"Uncharacterized protein MG027 homolog","reviewed":true,"short_name":"DUF1948","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf1948-pf09185.yaml","source_record_id":"Pfam:PF09185","source_record_label":"Domain of unknown function (DUF1948)","source_section":"canonical_examples","taxon_id":"NCBITaxon:272634","taxon_label":"Mycoplasmoides pneumoniae (strain ATCC 29342 / M129 / Subtype 1)","uniprot_accession":"P75084","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF09185","protein_label":"","reviewed":null,"short_name":"DUF1948","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf1948-pf09185.yaml","source_record_id":"Pfam:PF09185","source_record_label":"Domain of unknown function (DUF1948)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":3,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":2,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"Members of this family of Mycoplasma hypothetical proteins adopt a helical structure, with one central alpha-helix surrounded by five others, in a NusB-like fold. Their function has not, as yet, been determined [[cite:PUB00030162]].","domain_architectures":1,"interpro_id":"IPR015268","known_evidence_count":null,"matches":3,"name":"Domain of unknown function (DUF1948)","partial_evidence_count":null,"pfam_id":"PF09185","proteins":3,"proteomes":3,"short_name":"DUF1948","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09185","structures":1,"taxa":18,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF09185.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":3,"domain_architectures":1,"matches":3,"proteins":3,"proteomes":3,"structures":1,"taxa":18},"curation_status":"SEEDED","description":"Members of this family of Mycoplasma hypothetical proteins adopt a helical structure, with one central alpha-helix surrounded by five others, in a NusB-like fold. Their function has not, as yet, been determined [[cite:PUB00030162]].","id":"Pfam:PF09185","interpro_id":"InterPro:IPR015268","name":"Domain of unknown function (DUF1948)","pfam_id":"PF09185","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF1948","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09185"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF09185.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"b6ad34d523ff02bb5e1d9b99dffd149e2c45fee0f28f6b213d2e090db51c3761"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mycoplasmoides genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf1948-pf09185.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF09185","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf1948-pf09185.yaml"}],"pfam_ids":["PF09185"],"protein_name":"Uncharacterized protein MG027","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MAITVKGLTNKLTRTQRRIAVVEFIFSLLFFLPKEAEVIQADFLEYDTKERQLNEWQKLIVKAFSENIFSFQKKIEEQQLKNQLEIQTKYNKISGKKIDLLTTAVVLCALSEQKAHNTDKPLLISEALLIMDHYSQGAEKKQTHALLDKLL","sequence_length":151,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"2217d8871755179911cc2ec6cc88a6fd29537fe45f744c9cda56a0aa6ffc0e3a","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P47273.json","taxon_id":"243273","uniprot_accession":"P47273","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mycoplasmoides pneumoniae (strain ATCC 29342 / M129 / Subtype 1)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf1948-pf09185.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF09185","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf1948-pf09185.yaml"}],"pfam_ids":["PF09185"],"protein_name":"Uncharacterized protein MG027 homolog","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MCPSSFVLVIRLWFPPLTGAIVNGTTSKLTRTQRRIAIVEFIFATLFFLPKTADQIQAAFLDYDVPERPLNDWQKEIVKVFSERCVEFIELIENQQQRNQAEVQSKYNKVSGKKVDLLTKAVILCALSEQHAQATDKPLLISEALLIMDHYSQVPEKKQTHALLDKLL","sequence_length":168,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"08c187be9543dcff1d5417b96920b31a839afbf1cdd50fff6f3193577e3ebf81","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P75084.json","taxon_id":"272634","uniprot_accession":"P75084","uniprot_release":"2026_03"}],"pfam_id":"PF09185","short_name":"DUF1948","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}