{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF09428","protein_label":"Uncharacterized protein YNL050C","reviewed":true,"short_name":"DUF2011","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2011-pf09428.yaml","source_record_id":"Pfam:PF09428","source_record_label":"Fungal protein of unknown function (DUF2011)","source_section":"canonical_examples","taxon_id":"NCBITaxon:559292","taxon_label":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","uniprot_accession":"P53952","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF09428","protein_label":"Uncharacterized nucleolar protein C630.06c","reviewed":true,"short_name":"DUF2011","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2011-pf09428.yaml","source_record_id":"Pfam:PF09428","source_record_label":"Fungal protein of unknown function (DUF2011)","source_section":"canonical_examples","taxon_id":"NCBITaxon:284812","taxon_label":"Schizosaccharomyces pombe (strain 972 / ATCC 24843)","uniprot_accession":"Q9UUH6","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF09428","protein_label":"","reviewed":null,"short_name":"DUF2011","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2011-pf09428.yaml","source_record_id":"Pfam:PF09428","source_record_label":"Fungal protein of unknown function (DUF2011)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":927,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","description_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":2,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This is a family of fungal proteins whose function is unknown. They are distantly related to CUSTOS proteins [pfam:PF23999] from animals.","domain_architectures":29,"interpro_id":"IPR018555","known_evidence_count":null,"matches":1134,"name":"Fungal protein of unknown function (DUF2011)","partial_evidence_count":null,"pfam_id":"PF09428","proteins":1130,"proteomes":1107,"short_name":"DUF2011","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09428","structures":0,"taxa":2216,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF09428.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":927,"domain_architectures":29,"matches":1134,"proteins":1130,"proteomes":1107,"structures":0,"taxa":2216},"curation_status":"SEEDED","description":"This is a family of fungal proteins whose function is unknown. They are distantly related to CUSTOS proteins [pfam:PF23999] from animals.","id":"Pfam:PF09428","interpro_id":"InterPro:IPR018555","name":"Fungal protein of unknown function (DUF2011)","pfam_id":"PF09428","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF2011","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF09428"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF09428.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"d63af82edf8958dcb5cfbca8445f287008c6776b84945e77bb56a44258e2bb7d"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf2011-pf09428.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF09428","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf2011-pf09428.yaml"}],"pfam_ids":["PF09428"],"protein_name":"Uncharacterized protein YNL050C","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSEFKIVSRKDLYNEGEGLGEDYDSNSSSKNNSEHVEVLVPPTEFEFVEVERTDSSLDLKESNNSAHEQKEEKQEEFEFPLFSFGVVEASTSPAQEEQGSSTQEKDTPQTEVSLMKISLKEPEEEIINQERPKDYYFASYSADQKLQFQQSSIDYDVIIQESTKILEDDLRIRDKWPYCQGRIIDLYKHNARIELEQQKELKIKKRRPGQKQRAAKKLALERTKERDTKAREIKKQLKKKFHKRGGKKNKKKVPLNPLAKAGSTPKFRTE","sequence_length":270,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"e9563127ffe83c3a2b7e731543ac752c702d27afbe33e3427cb45f0f417b7157","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P53952.json","taxon_id":"559292","uniprot_accession":"P53952","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Schizosaccharomyces pombe (strain 972 / ATCC 24843)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf2011-pf09428.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF09428","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf2011-pf09428.yaml"}],"pfam_ids":["PF09428"],"protein_name":"Uncharacterized nucleolar protein C630.06c","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"METVKVTRKDLLLSPENKEIDSLDDVSALLSQRLSNVFEFSIASEEVQSDEVFEDTYPNDDQATFNLFSDVNTVVTKVTEPSIKNSRPLNYYILEDSPERQRQLQASVFTYDQLMKAKEEKWPACQKLHKVVSIKKEESKHRRRPSKKRRIRMKLLREKEEQLKRQAMAAKRNRFRKNVRKLPNKKKH","sequence_length":188,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"330b8bb83956e6e2ab07dbb43195e8419dd214a32c76bc1680c1956e936c358f","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q9UUH6.json","taxon_id":"284812","uniprot_accession":"Q9UUH6","uniprot_release":"2026_03"}],"pfam_id":"PF09428","short_name":"DUF2011","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}
