{"cross_mech":[],"family":{"alphafold_models":1624,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents the probable inorganic carbon transporter subunit DabA, which is part of an energy-coupled inorganic carbon pump together with DabB subunit in DAB operons (DAB1 and DAB2), found in a wide range of bacteria and archaea. Members of this family were previously known as UPF0753. DAB operon is required for CO2 concentrating mechanisms [[cite:PUB00093673]]. The substrate of this subunit may be CO2 rather than carbonate ions based on kinetic calculations and in experimental assays in which E.coli was deleted of its carbonic anhydrase genes and expression of DAB2 operon restores its growth. Structural homology modelling suggests that DabA contains a domain that is distantly homologous to a type II beta-carbonic anhydrase (CA).","domain_architectures":7,"interpro_id":"IPR018752","known_evidence_count":null,"matches":2419,"name":"Probable inorganic carbon transporter subunit DabA","partial_evidence_count":null,"pfam_id":"PF10070","proteins":2360,"proteomes":2033,"short_name":"DabA","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10070","structures":3,"taxa":3561,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF10070.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":1624,"domain_architectures":7,"matches":2419,"proteins":2360,"proteomes":2033,"structures":3,"taxa":3561},"curation_status":"SEEDED","description":"This entry represents the probable inorganic carbon transporter subunit DabA, which is part of an energy-coupled inorganic carbon pump together with DabB subunit in DAB operons (DAB1 and DAB2), found in a wide range of bacteria and archaea. Members of this family were previously known as UPF0753. DAB operon is required for CO2 concentrating mechanisms [[cite:PUB00093673]]. The substrate of this subunit may be CO2 rather than carbonate ions based on kinetic calculations and in experimental assays in which E.coli was deleted of its carbonic anhydrase genes and expression of DAB2 operon restores its growth. Structural homology modelling suggests that DabA contains a domain that is distantly homologous to a type II beta-carbonic anhydrase (CA).","id":"Pfam:PF10070","interpro_id":"InterPro:IPR018752","name":"Probable inorganic carbon transporter subunit DabA","pfam_id":"PF10070","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"DabA","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10070"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF10070.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"a6077fbc2330fb41bbb7a63ded7dcde7eddee19eac1742b0d58733b214792700"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Halothiobacillus neapolitanus (strain ATCC 23641 / DSM 15147 / CIP 104769 / NCIMB 8539 / c2)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/daba-pf10070.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF10070","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/daba-pf10070.yaml"}],"pfam_ids":["PF10070"],"protein_name":"Probable inorganic carbon transporter subunit 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subtilis (strain 168)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/daba-pf10070.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF10070","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/daba-pf10070.yaml"}],"pfam_ids":["PF10070"],"protein_name":"Probable inorganic carbon transporter subunit 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