{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF10360","protein_label":"","reviewed":null,"short_name":"DUF2433","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf2433-ipr018829.yaml","source_record_id":"InterPro:IPR018829","source_record_label":"Domain of unknown function DUF2433","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF10360","protein_label":"Uncharacterized protein C16H5.12c","reviewed":true,"short_name":"DUF2433","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2433-pf10360.yaml","source_record_id":"Pfam:PF10360","source_record_label":"Protein of unknown function (DUF2433)","source_section":"canonical_examples","taxon_id":"NCBITaxon:284812","taxon_label":"Schizosaccharomyces pombe (strain 972 / ATCC 24843)","uniprot_accession":"O42947","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF10360","protein_label":"","reviewed":null,"short_name":"DUF2433","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2433-pf10360.yaml","source_record_id":"Pfam:PF10360","source_record_label":"Protein of unknown function (DUF2433)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":1097,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":1,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This is a conserved 120 residue region of a family of proteins found in fungi. The function is not known.","domain_architectures":28,"interpro_id":"IPR018829","known_evidence_count":null,"matches":1386,"name":"Protein of unknown function (DUF2433)","partial_evidence_count":null,"pfam_id":"PF10360","proteins":1384,"proteomes":1326,"short_name":"DUF2433","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10360","structures":0,"taxa":2784,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF10360.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":1097,"domain_architectures":28,"matches":1386,"proteins":1384,"proteomes":1326,"structures":0,"taxa":2784},"curation_status":"SEEDED","description":"This is a conserved 120 residue region of a family of proteins found in fungi. The function is not known.","id":"Pfam:PF10360","interpro_id":"InterPro:IPR018829","name":"Protein of unknown function (DUF2433)","pfam_id":"PF10360","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF2433","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10360"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF10360.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"54e946f27f51370cfd2864a865c741151bc7ae1d435ec5a554f6112953c33080"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Schizosaccharomyces pombe (strain 972 / ATCC 24843)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf2433-pf10360.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF10360","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf2433-pf10360.yaml"}],"pfam_ids":["PF10360"],"protein_name":"Uncharacterized protein C16H5.12c","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSVDTAKSDIQAEPSTGTLENKSSKTYSDSENNSTLDVSAQVLTLDNKSRILCIADVRGELSLINSLVEETNASCVIHTGDFGFFERSSLPSISERTLRHIVQFSPLIKKLPRSKNFDYYPSNPIGDLKNSIASHPDCLLSELPQFLSQEKKFSVPVYVVWGACEDVHVLEKFRSGEYSIPNLNIVDELHSYLLQIGDMKIRLLGLGGPYVPFKLFDNGDGKGTIAGGQGTMWTTILQMGELIETAKSLLDREEARIFITHHPIGREGVLSQLATACQADLTLSAGLHFRYGASYNEFCVNHSPEHYLQKLSAARAQFMEVYDTVKAEVEKMVTPEQHHLINNVVRLVSRMPDATNSYAMNNMLPGTAFKNLWNFNLLDASFGWTVFVVENGHVQVESKSHGFNLGYRRMASRRNENYASHIPRSTSENTGTYYYANNRLVESQAQFTKNREATATPTEEEQIEGYDQEHTDELGMSRANTTEESAETHEVIEEKSGPPAAEEEPISGVAEKPSPNEEEQPAIGGKEEVDVEEVTKGTGNLELGETTTEVTILEQENAANVTRSQAQEGRRTDMQKGNDREFRQYSGEQRYERCGFHITPCNSEEEARSYFKDGTDSLITNIQIRTSLNRYKSPQAPQNVNPTNYAYVFVENQNAVSKALGSIKVPEGVRVNIMRDDSYYRQNRGWYRNNRMEGHGTGMRTNRGRGRGGRMNRMQHPRPLQSGGSVNKQSAEPTTHG","sequence_length":737,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"338e457754328d1576f8b71071e482c9766858e236f84e444d82cb79fe58e054","sequence_version":3,"source_url":"https://rest.uniprot.org/uniprotkb/O42947.json","taxon_id":"284812","uniprot_accession":"O42947","uniprot_release":"2026_03"}],"pfam_id":"PF10360","short_name":"DUF2433","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}
