{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF10694","protein_label":"Uncharacterized protein YhhM","reviewed":true,"short_name":"DUF2500","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2500-pf10694.yaml","source_record_id":"Pfam:PF10694","source_record_label":"Protein of unknown function (DUF2500)","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P37615","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF10694","protein_label":"","reviewed":null,"short_name":"DUF2500","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2500-pf10694.yaml","source_record_id":"Pfam:PF10694","source_record_label":"Protein of unknown function (DUF2500)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF10694","protein_label":"Uncharacterized protein YhhM","reviewed":true,"short_name":"DUF2500","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/2-40-50-660-2-40-50-660.yaml","source_record_id":"CATH:2.40.50.660","source_record_label":"CATH homologous superfamily 2.40.50.660","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P37615","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":911,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":1,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":2},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"The members of this family are largely confined to the Gammaproteobacteria. The function is not known.","domain_architectures":4,"interpro_id":"IPR019635","known_evidence_count":null,"matches":1540,"name":"Protein of unknown function (DUF2500)","partial_evidence_count":null,"pfam_id":"PF10694","proteins":1537,"proteomes":1360,"short_name":"DUF2500","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10694","structures":3,"taxa":1954,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF10694.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":911,"domain_architectures":4,"matches":1540,"proteins":1537,"proteomes":1360,"structures":3,"taxa":1954},"curation_status":"SEEDED","description":"The members of this family are largely confined to the Gammaproteobacteria. The function is not known.","id":"Pfam:PF10694","interpro_id":"InterPro:IPR019635","name":"Protein of unknown function (DUF2500)","pfam_id":"PF10694","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF2500","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10694"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF10694.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"6a5a17cd44fcfdc9a145e5360b8dd0f953597453fa2da1805af4a446a67d2185"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf2500-pf10694.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF10694","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf2500-pf10694.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/2-40-50-660-2-40-50-660.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:2.40.50.660","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/2-40-50-660-2-40-50-660.yaml"}],"pfam_ids":["PF10694"],"protein_name":"Uncharacterized protein YhhM","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSKPPLFFIVIIGLIVVAASFRFMQQRREKADNDMAPLQQKLVVVSNKREKPINDRRSRQQEVTPAGTSIRYEASFKPQSGGMEQTFRLDAQQYHALTVGDKGTLSYKGTRFVSFVGEQ","sequence_length":119,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"ba880e7388c4735983ef4577aaf33de2e1b7be6c4b82c5b9225656832b6f03bd","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P37615.json","taxon_id":"83333","uniprot_accession":"P37615","uniprot_release":"2026_03"}],"pfam_id":"PF10694","short_name":"DUF2500","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}