{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF10696","protein_label":"Uncharacterized protein YjjA","reviewed":true,"short_name":"DUF2501","source_category":"function/protein_family/ncbifam","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/protein_family/ncbifam/hypothetical-protein-nf008663.yaml","source_record_id":"NCBIfam:NF008663","source_record_label":"hypothetical protein","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P18390","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF10696","protein_label":"Uncharacterized protein YjjA","reviewed":true,"short_name":"DUF2501","source_category":"function/protein_family/ncbifam","source_mech":"ProteinTraitsMech","source_path":"data/traits/function/protein_family/ncbifam/hypothetical-protein-nf008666.yaml","source_record_id":"NCBIfam:NF008666","source_record_label":"hypothetical protein","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P18390","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF10696","protein_label":"Uncharacterized protein YjjA","reviewed":true,"short_name":"DUF2501","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2501-pf10696.yaml","source_record_id":"Pfam:PF10696","source_record_label":"Protein of unknown function (DUF2501)","source_section":"canonical_examples","taxon_id":"NCBITaxon:83333","taxon_label":"Escherichia coli (strain K12)","uniprot_accession":"P18390","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF10696","protein_label":"","reviewed":null,"short_name":"DUF2501","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2501-pf10696.yaml","source_record_id":"Pfam:PF10696","source_record_label":"Protein of unknown function (DUF2501)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":511,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":1,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":3},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"Members of this family are all Proteobacteria. Several are annotated as being YjjA or YjjA-like, but this protein is uncharacterised.","domain_architectures":4,"interpro_id":"IPR019637","known_evidence_count":null,"matches":847,"name":"Protein of unknown function (DUF2501)","partial_evidence_count":null,"pfam_id":"PF10696","proteins":838,"proteomes":809,"short_name":"DUF2501","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10696","structures":0,"taxa":1101,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF10696.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":511,"domain_architectures":4,"matches":847,"proteins":838,"proteomes":809,"structures":0,"taxa":1101},"curation_status":"SEEDED","description":"Members of this family are all Proteobacteria. Several are annotated as being YjjA or YjjA-like, but this protein is uncharacterised.","id":"Pfam:PF10696","interpro_id":"InterPro:IPR019637","name":"Protein of unknown function (DUF2501)","pfam_id":"PF10696","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF2501","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10696"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF10696.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"c0552693fd3426e11210503736df1df8185a8a62cc7d889e6089e676c3015c31"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/hypothetical-protein-nf008663.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:NF008663","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/hypothetical-protein-nf008663.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/hypothetical-protein-nf008666.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:NF008666","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/hypothetical-protein-nf008666.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf2501-pf10696.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF10696","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf2501-pf10696.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P18390","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF10696"],"protein_name":"Uncharacterized protein YjjA","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"c5d3cf69e410e03c84953e22422439492445939ab69f62c74e0d66c9832ab01a","sequence_version":3,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MMKTVKHLLCCAIAASALISTGVHAASWKDALSSAASELGNQNSTTQEGGWSLASLTNLLSSGNQALSADNMNNAAGILQYCAKQKLASVTDAENIKNQVLEKLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGLNFIS","sequence_length":164,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"c5d3cf69e410e03c84953e22422439492445939ab69f62c74e0d66c9832ab01a","sequence_version":3,"source_url":"https://rest.uniprot.org/uniprotkb/P18390.json","taxon_id":"83333","uniprot_accession":"P18390","uniprot_release":"2026_03"}],"pfam_id":"PF10696","short_name":"DUF2501","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}