{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF10872","protein_label":"Uncharacterized 5.8 kDa protein","reviewed":true,"short_name":"DUF2740","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2740-pf10872.yaml","source_record_id":"Pfam:PF10872","source_record_label":"Protein of unknown function (DUF2740)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10742","taxon_label":"Escherichia phage HK022","uniprot_accession":"Q37928","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF10872","protein_label":"Uncharacterized 5.8 kDa protein","reviewed":true,"short_name":"DUF2740","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2740-pf10872.yaml","source_record_id":"Pfam:PF10872","source_record_label":"Protein of unknown function (DUF2740)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10754","taxon_label":"Salmonella phage P22","uniprot_accession":"Q38661","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF10872","protein_label":"","reviewed":null,"short_name":"DUF2740","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf2740-pf10872.yaml","source_record_id":"Pfam:PF10872","source_record_label":"Protein of unknown function (DUF2740)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":6,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":2,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family of proteins with unknown function has a highly conserved sequence.","domain_architectures":1,"interpro_id":"IPR022626","known_evidence_count":null,"matches":21,"name":"Protein of unknown function (DUF2740)","partial_evidence_count":null,"pfam_id":"PF10872","proteins":21,"proteomes":19,"short_name":"DUF2740","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10872","structures":0,"taxa":65,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF10872.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":6,"domain_architectures":1,"matches":21,"proteins":21,"proteomes":19,"structures":0,"taxa":65},"curation_status":"SEEDED","description":"This family of proteins with unknown function has a highly conserved sequence.","id":"Pfam:PF10872","interpro_id":"InterPro:IPR022626","name":"Protein of unknown function (DUF2740)","pfam_id":"PF10872","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF2740","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF10872"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF10872.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"ec4db68184267e008b3a066a0a633e8aa98e3b662e49f3de7bec9cb66a7e916f"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia phage HK022","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf2740-pf10872.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF10872","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf2740-pf10872.yaml"}],"pfam_ids":["PF10872"],"protein_name":"Uncharacterized 5.8 kDa protein","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MTKQLSPYQDKIHKHILRDRFLSSFKQPGRFRAELEKVKLMQKEKGHE","sequence_length":48,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"2d5820af51c3f7d7965ff7668139102a8bec0ce947232aa6eefc40fd5a95a46e","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q37928.json","taxon_id":"10742","uniprot_accession":"Q37928","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Salmonella phage P22","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf2740-pf10872.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF10872","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf2740-pf10872.yaml"}],"pfam_ids":["PF10872"],"protein_name":"Uncharacterized 5.8 kDa protein","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MPKQLSPDQDKLHKNILRDRFLSSFKQPGRFRAELEKVKLILKRKGHE","sequence_length":48,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"9b3af2d782f64ee1e5c10a3f370e0166f5f3acaa21bbbeb579d31fd9a7c6571e","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q38661.json","taxon_id":"10754","uniprot_accession":"Q38661","uniprot_release":"2026_03"}],"pfam_id":"PF10872","short_name":"DUF2740","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}