{"cross_mech":[],"family":{"alphafold_models":2669,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This eukaryotic family of proteins includes a group of fungal proteins, including Egh16 from Erysiphe graminis f.sp. hordei and its homologues [[cite:PUB00086549],[cite:PUB00086548]]. They are found in pathogenic fungi and may play important roles during the early infection stage in fungal pathogens [[cite:PUB00086551]].","domain_architectures":27,"interpro_id":"IPR021476","known_evidence_count":null,"matches":3135,"name":"Egh16-like virulence factor","partial_evidence_count":null,"pfam_id":"PF11327","proteins":3120,"proteomes":721,"short_name":"Egh16-like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11327","structures":0,"taxa":1537,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF11327.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":2669,"domain_architectures":27,"matches":3135,"proteins":3120,"proteomes":721,"structures":0,"taxa":1537},"curation_status":"SEEDED","description":"This eukaryotic family of proteins includes a group of fungal proteins, including Egh16 from Erysiphe graminis f.sp. hordei and its homologues [[cite:PUB00086549],[cite:PUB00086548]]. They are found in pathogenic fungi and may play important roles during the early infection stage in fungal pathogens [[cite:PUB00086551]].","id":"Pfam:PF11327","interpro_id":"InterPro:IPR021476","name":"Egh16-like virulence factor","pfam_id":"PF11327","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Egh16-like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11327"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF11327.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"e6bb3a46eec2cc67031134c062f2c29bb8c3ee66ccd84841c1309d162b305bbf"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Arthrobotrys flagrans","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/egh16-like-pf11327.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF11327","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/egh16-like-pf11327.yaml"}],"pfam_ids":["PF11327"],"protein_name":"Lytic polysaccharide monooxygenase trsA","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MHFSTLLTSVTIALVGIVDVTSAHCVFVDAYGNAKPAIRGHGLGFGPFTPRKGTHLLPHQRDIAVFDDRVVHTAWNKKYRPYGCGCSAQTSAVWYDKNMRTKWKQKGSWLFSEVTPAAAFINVKKSVDFLAFQETKGVTRSCLATGRKGLKTGIPQVTAGGKLHILVYQVNLDGGGPFKCKIDYKGNGASWTTSLAVTKNCPGDQSSSFNWPGIGKTCWVSIAMPKNLNCHGKFGTNGRIEDVCLVRCENNAANGPFGGCVPIKQFRPAKKVVTEKIGTKKVVSTKIVTRKQYITTRKTIRVPVTKIIKVPAPKPTKVLPPRIKVVTVTRNTVVILTKGGVRKTTSVTKGGVITVTETVKVQPPKTSTVTVYEDEVFEEEIPEGGNDDDDDEDDASEVEADPANDDANKVAPKAAQATQEPTPEEIEAAIGGEEFDEDDIEKLKNEKVSKEDKELLQEAAESKDQKVEFEDIPDTYKLRFHRE","sequence_length":483,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"de5f9574362d0f3be47c62f7ddabba6ac83ae6b220b1c68912b26f3188a538aa","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/A0A437A807.json","taxon_id":"97331","uniprot_accession":"A0A437A807","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/egh16-like-pf11327.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF11327","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/egh16-like-pf11327.yaml"}],"pfam_ids":["PF11327"],"protein_name":"Secreted virulence factor ELV1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MVSFTDFLSASAVLAIAHGHGVILNAQGPAGPGSVGFQVNPDLPRNCTTISPCQQDATLIRDAEIQQNLVNECGRTELAGNIDIGENTENALAANAVTQVTKGSSIEVTIHQVNADGAGPYVCDLDQTSNGLRLVGQIPLKVTNNVPGANGFSQAKAQQFKMTVTLPDDLACTGASTGNVCTVRCRNNAVAGPFGGCFPVQQTDIEPKVNTPANLASAQSLELTLAQTQNNQADLVKALEANANAGTDEAKQNLAAVEAILNINPTTKAAPVQTPDLPAAPAASSDTVTSAPAEATEGAGAGAGADNGIGNGNGNAGNGNNRGGNAGGNNNNNNGNGAGNGNGNGRGRNGGNANRNGGAGNAGNAGAGGGRFGDNNKRSIGLRWSNRMA","sequence_length":389,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"825e3958914800643e0950cabd2d8f30395ce26689f2cf2779c60cadc180b928","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/G2X0V4.json","taxon_id":"498257","uniprot_accession":"G2X0V4","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/egh16-like-pf11327.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF11327","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/egh16-like-pf11327.yaml"}],"pfam_ids":["PF11327"],"protein_name":"Appressoria-specific virulence factor GAS2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MKYTSAILISAFAATNVFAHGVVTEVQGANGVTLPGLTAIDGTPRDCPNPGCGSEADTAIIRDRELGTSRASALGRTQGGGPVDAAKMIELFMDGASVNKSDVVAARERHAANLARRATLLPRAGGGTSTPKGTEETGVKAATGIAATKGLPTTNDDGTINIVFHQVNQDGAGPLTADIDSTSGGQDVSAFQKAKITTNVPGLGIAGLSAAQTMDFPVAVQMPAGATCSGSVGGANNVCIARLRNAAVTGPFGGSVAFTQSPAARKRAIEYNLAKRRFARSLATDEEDDE","sequence_length":290,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"de19eb50244bdd23fac75b15063999ab05797ba505936c0513d92519ddad76ac","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/G4NF50.json","taxon_id":"242507","uniprot_accession":"G4NF50","uniprot_release":"2026_03"}],"pfam_id":"PF11327","short_name":"Egh16-like","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}