{"cross_mech":[],"family":{"alphafold_models":161,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain is found at the N-terminal end of alpha-(1->3)- arabinofuranosyltransferase from Mycolicibacterium smegmatis (AftD, [ec:2.4.2.47]), which is involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan -peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. It catalyses the addition of an arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG [[cite:PUB00086410]]. This domain shows mixed alpha/beta folds homologous to other solved GT-C glycosyltransferase structures [[cite:PUB00155574]].","domain_architectures":18,"interpro_id":"IPR021798","known_evidence_count":null,"matches":1717,"name":"Alpha-(1->3)-arabinofuranosyltransferase, N-terminal GT-C domain","partial_evidence_count":null,"pfam_id":"PF11847","proteins":1673,"proteomes":1560,"short_name":"GT-C_AftD","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11847","structures":3,"taxa":1916,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF11847.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":161,"domain_architectures":18,"matches":1717,"proteins":1673,"proteomes":1560,"structures":3,"taxa":1916},"curation_status":"SEEDED","description":"This domain is found at the N-terminal end of alpha-(1->3)- arabinofuranosyltransferase from Mycolicibacterium smegmatis (AftD, [ec:2.4.2.47]), which is involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan -peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. It catalyses the addition of an arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG [[cite:PUB00086410]]. This domain shows mixed alpha/beta folds homologous to other solved GT-C glycosyltransferase structures [[cite:PUB00155574]].","id":"Pfam:PF11847","interpro_id":"InterPro:IPR021798","name":"Alpha-(1->3)-arabinofuranosyltransferase, N-terminal GT-C domain","pfam_id":"PF11847","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"GT-C_AftD","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11847"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF11847.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"340c785c085996bd8cd8d659eba5747bdd3d41004a0ba1da714c868ae56bc2f4"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mycolicibacterium smegmatis (strain ATCC 700084 / 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tuberculosis (strain ATCC 25618 / 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