{"cross_mech":[],"family":{"alphafold_models":3480,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain is functionally uncharacterised. This domain is found at the C-terminal of a family of 4Fe-4S, iron-sulphur cluster binding proteins, including Lactate utilisation protein B (LutB). These proteins have a perfect 4Fe-4S binding motif C-x(2)-C-x(2)-C-x(3)-CP followed by either a perfect or imperfect (the first Cys replaced by Ser) second copy. Members probably bind two 4Fe-4S iron-sulphur clusters. This domain is found in LutB proteins in association with the LUD domain ([pfam:PF02589]) and usually Fer4_8 ([pfam:PF13183]). The LutABC operon is involved in lactate-utilisation and is essential [[cite:PUB00076952],[cite:PUB00053899]].","domain_architectures":9,"interpro_id":"IPR024569","known_evidence_count":null,"matches":5783,"name":"Lactate utilisation protein B, C-terminal","partial_evidence_count":null,"pfam_id":"PF11870","proteins":5783,"proteomes":5267,"short_name":"LutB_C","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11870","structures":0,"taxa":7254,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF11870.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":3480,"domain_architectures":9,"matches":5783,"proteins":5783,"proteomes":5267,"structures":0,"taxa":7254},"curation_status":"SEEDED","description":"This domain is functionally uncharacterised. This domain is found at the C-terminal of a family of 4Fe-4S, iron-sulphur cluster binding proteins, including Lactate utilisation protein B (LutB). These proteins have a perfect 4Fe-4S binding motif C-x(2)-C-x(2)-C-x(3)-CP followed by either a perfect or imperfect (the first Cys replaced by Ser) second copy. Members probably bind two 4Fe-4S iron-sulphur clusters. This domain is found in LutB proteins in association with the LUD domain ([pfam:PF02589]) and usually Fer4_8 ([pfam:PF13183]). The LutABC operon is involved in lactate-utilisation and is essential [[cite:PUB00076952],[cite:PUB00053899]].","id":"Pfam:PF11870","interpro_id":"InterPro:IPR024569","name":"Lactate utilisation protein B, 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