{"cross_mech":[],"family":{"alphafold_models":2684,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"The COG complex comprises eight proteins (COG1-8) and plays critical roles in Golgi structure and function [[cite:PUB00012274]]. It is necessary for retrograde trafficking in the Golgi apparatus and for protein glycosylation [[cite:PUB00097774]]. COG complex, together with exocyst, Golgi-associated retrograde protein (GARP) and Dsl1 complexes, is a member of the CATHR (complexes associated with tethering containing helical rods) family sharing an evolutionary origin and structural features [[cite:PUB00100047]]. This domain represents the C-terminal of COG complex subunit 2 and consists of a conserved alpha-helical bundle. In Arabidopsis, COG2 forms a complex with FPP3/VETH1 and FPP2/VETH2 and ensures the correct secondary cell wall (SCW) deposition pattern by recruiting exocyst components to cortical microtubules in xylem cells during secondary cell wall deposition [[cite:PUB00097774]].","domain_architectures":68,"interpro_id":"IPR024603","known_evidence_count":null,"matches":3267,"name":"COG complex component, COG2, C-terminal","partial_evidence_count":null,"pfam_id":"PF12022","proteins":3152,"proteomes":2247,"short_name":"COG2_C","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12022","structures":0,"taxa":6622,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF12022.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":2684,"domain_architectures":68,"matches":3267,"proteins":3152,"proteomes":2247,"structures":0,"taxa":6622},"curation_status":"SEEDED","description":"The COG complex comprises eight proteins (COG1-8) and plays critical roles in Golgi structure and function [[cite:PUB00012274]]. It is necessary for retrograde trafficking in the Golgi apparatus and for protein glycosylation [[cite:PUB00097774]]. COG complex, together with exocyst, Golgi-associated retrograde protein (GARP) and Dsl1 complexes, is a member of the CATHR (complexes associated with tethering containing helical rods) family sharing an evolutionary origin and structural features [[cite:PUB00100047]]. This domain represents the C-terminal of COG complex subunit 2 and consists of a conserved alpha-helical bundle. In Arabidopsis, COG2 forms a complex with FPP3/VETH1 and FPP2/VETH2 and ensures the correct secondary cell wall (SCW) deposition pattern by recruiting exocyst components to cortical microtubules in xylem cells during secondary cell wall deposition [[cite:PUB00097774]].","id":"Pfam:PF12022","interpro_id":"InterPro:IPR024603","name":"COG complex component, COG2, C-terminal","pfam_id":"PF12022","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"COG2_C","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12022"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF12022.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"4b98954845e97aaafcefa8edfd686fe528d2ac9287e1c69b7aba0918430843d7"}},"protein_examples":{"candidate_count":5,"discovery_scanned":true,"example_count":5,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Arabidopsis thaliana","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/regulation-of-exocyst-localization-go0060178.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0060178","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/regulation-of-exocyst-localization-go0060178.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/cog-complex-component-cog2-c-terminal-ipr024603.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024603","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/cog-complex-component-cog2-c-terminal-ipr024603.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/conserved-oligomeric-golgi-complex-subunit-2-n-terminal-ipr024602.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024602","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/conserved-oligomeric-golgi-complex-subunit-2-n-terminal-ipr024602.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/repeat/pfam/cog2-c-pf12022.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12022","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/repeat/pfam/cog2-c-pf12022.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/repeat/pfam/cog2-n-pf06148.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF06148","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/repeat/pfam/cog2-n-pf06148.yaml"}],"pfam_ids":["PF06148","PF12022"],"protein_name":"Conserved oligomeric Golgi complex subunit 2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSDLVATSPSPSSAPRSATDFFSDPYDSHPLWFKPSLFLSPNFDSESYISELRTFVPFDTLRSELRSHLASLNRELVDLINRDYADFVNLSTKLVDIDAAVVRMRAPLLELREKITGFRGSVEAALFALRNGLQQRSDAAAAREVLELLLDTFHVVSKVEKLIKVLPSTPSDWQNEDANSMGRSSMNDENSTQQDGTTMRETQSMLLERIASEMNRLKFYMAHAQNLPFIENMEKRIQSASVLLDASLGHCFIDGLNNSDTSVLYNCLRAYAAIDNTNAAEEIFRTTIVAPFIQKIITHETTTNAAGTSEDELENDYKQIKHFIAKDCKMLLEISSTDKSGLHVFDFLANSILKEVLWAIQKVKPGAFSPGRPTEFLKNYKASLDFLAYLEGYCPSRSAVTKFRAEAICVEFMKQWNVGVYFSLRFQEIAGALDSALTSPSLVFIQDSDKESSLNLILRQSDTLLECLRSCWKEDVLVFSAADKFLRLTLQLLSRYSFWVSSALNNRKSNASPSPGCEWAVSATAEDFVYVIHDVNCLVSEVCGDYLGHISQYLSSSSTEVLDVVRISIEQGGVSLEKVLPLLTKTIIDVIVDKSVEDLRQLRGITATFRMTNKPLPVRHSPYVVGLLRPVKAFLEGDKARNYLTQKTKEELLHGSVSEITRRYYELAADVVSVARKTQSSLQKLRQNAQRRGGAASGVSDQNVSETDKMCMQLFLDIQEYGRNVSALGLKPADIPEYCSFWQCVAPADRQNSISV","sequence_length":756,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"80a4a6a749156748fcac880fe5e0d658003db2cd86dafa7864aa754c5eb8618e","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/F4JRR1.json","taxon_id":"3702","uniprot_accession":"F4JRR1","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/cog-complex-component-cog2-c-terminal-ipr024603.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024603","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/cog-complex-component-cog2-c-terminal-ipr024603.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/conserved-oligomeric-golgi-complex-subunit-2-n-terminal-ipr024602.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024602","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/conserved-oligomeric-golgi-complex-subunit-2-n-terminal-ipr024602.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/repeat/pfam/cog2-c-pf12022.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12022","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/repeat/pfam/cog2-c-pf12022.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/repeat/pfam/cog2-n-pf06148.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF06148","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/repeat/pfam/cog2-n-pf06148.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:Q14746","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF06148","PF12022"],"protein_name":"Conserved oligomeric Golgi complex subunit 2","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"340a9338edb0878c24c4d49bc8d85c932d6e42bdf9f00ba7cb73f671753d88a6","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MEKSRMNLPKGPDTLCFDKDEFMKEDFDVDHFVSDCRKRVQLEELRDDLELYYKLLKTAMVELINKDYADFVNLSTNLVGMDKALNQLSVPLGQLREEVLSLRSSVSEGIRAVDERMSKQEDIRKKKMCVLRLIQVIRSVEKIEKILNSQSSKETSALEASSPLLTGQILERIATEFNQLQFHAVQSKGMPLLDKVRPRIAGITAMLQQSLEGLLLEGLQTSDVDIIRHCLRTYATIDKTRDAEALVGQVLVKPYIDEVIIEQFVESHPNGLQVMYNKLLEFVPHHCRLLREVTGGAISSEKGNTVPGYDFLVNSVWPQIVQGLEEKLPSLFNPGNPDAFHEKYTISMDFVRRLERQCGSQASVKRLRAHPAYHSFNKKWNLPVYFQIRFREIAGSLEAALTDVLEDAPAESPYCLLASHRTWSSLRRCWSDEMFLPLLVHRLWRLTLQILARYSVFVNELSLRPISNESPKEIKKPLVTGSKEPSITQGNTEDQGSGPSETKPVVSISRTQLVYVVADLDKLQEQLPELLEIIKPKLEMIGFKNFSSISAALEDSQSSFSACVPSLSSKIIQDLSDSCFGFLKSALEVPRLYRRTNKEVPTTASSYVDSALKPLFQLQSGHKDKLKQAIIQQWLEGTLSESTHKYYETVSDVLNSVKKMEESLKRLKQARKTTPANPVGPSGGMSDDDKIRLQLALDVEYLGEQIQKLGLQASDIKSFSALAELVAAAKDQATAEQP","sequence_length":738,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"340a9338edb0878c24c4d49bc8d85c932d6e42bdf9f00ba7cb73f671753d88a6","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q14746.json","taxon_id":"9606","uniprot_accession":"Q14746","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Caenorhabditis elegans","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/cog-complex-component-cog2-c-terminal-ipr024603.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024603","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/cog-complex-component-cog2-c-terminal-ipr024603.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/conserved-oligomeric-golgi-complex-subunit-2-n-terminal-ipr024602.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024602","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/conserved-oligomeric-golgi-complex-subunit-2-n-terminal-ipr024602.yaml"}],"pfam_ids":["PF06148","PF12022"],"protein_name":"Conserved oligomeric Golgi complex subunit 2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGTLHGEKTMFASPNTFYIDESKLCFNKTHFNREDFNVERFMNLARQKSDLKTIQQDLRLYLKSVQNSMIELINDDYADFVHLSSNLVSLQDSLNKIEQDINRIWDEFKESTRESVGMAERIEQKCDELCSNREKQIEIRDRIYFLVAIEKLSEMLLHPPRKCSALWLQKAASFASELKGSTFPHSEEENAAEKIILSQLEAVLCAEGVRSAAGDCQNLPLIYSILSLTESTHSLTALLVSDLLYAEFVNEKHDESNQLKLLKQVFESVKKMRETWAEKMGTEHFRGNIRRFLDETLLTFILTFIDKCMGAVAVPSDTRLFHECFLLTQEFIDNWPSSHTCRAMLKSIRDKFNLLVYFKLETHRFGKQCDQLMSPEMFAEPETSENRENTPQLHCGVSRAIITAIEHVWSDDVYLPPIVDKLWDFTLKLLLKHFSWSQTMKNYFMEEKRDWTSMVTLRSDTGNLHQLVFDFALESIWGKFHDITVDTAPFGQCLTKHGRSIDSLCVQIDDSIIEMFSEVLHQEIAQVSDVPKQYRWTKKSPPTTHSKYVVTAIEMVENLKEKLCCEEHPHTDEIVRKVNLSAFNYFVGKGNEVLDSVEATGSSLSRFKRKTTTDSGSTVTDDDKIKQQIYHDAKYFLSYAENLVFSQADLTGLQEVVNRFDKDARSAIVQEKNQNEEAGNA","sequence_length":681,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"e0ada702b72cf04ca2bc8c0d6b184a4ae2f83f466bbeb365b2dde33466fe68d5","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q21444.json","taxon_id":"6239","uniprot_accession":"Q21444","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/cog-complex-component-cog2-c-terminal-ipr024603.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024603","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/cog-complex-component-cog2-c-terminal-ipr024603.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/conserved-oligomeric-golgi-complex-subunit-2-n-terminal-ipr024602.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024602","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/conserved-oligomeric-golgi-complex-subunit-2-n-terminal-ipr024602.yaml"}],"pfam_ids":["PF06148","PF12022"],"protein_name":"Conserved oligomeric Golgi complex subunit 2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MEKRRMNLPTGPDTLCFDKDEFMKEDFDVDHFVSDCRKRVQLEELRDDLELYYKLLKTAMVELINKDYADFVNLSTNLVGMDRALNQLSVPLGQLREEVLSLRSSVSEGILAVDERMSKQEDIRKKKMSVLRLIQVIRSVEKIEKILNSQSSKDVSSQEASSPLLTGQVLERIATEFNQLQFHAVQSKGMPLLDKVRPRIAGITAMLQQSLEGLLLEGLQTSDVDIVRHCLRTYATIDKTQDAEALVGQVLVKPYVNEVIVEQFVESHPSSLQLMYNKLLEFVPHHCRLLREVTGGAVSSEKGTIVPGYDFLVNSVWPEIVRGLEEKLPSLFNPGDPDAFHQKYTVSMDFVQRFERQCGSQASVKRLRAHPAYHNFSNKWNLPVYFQIRFREVAGSLEAALTDGLEDAPAGSPYCLLASHRTWISLGKCWSDEMFLPLLAHRLWRLTLQILARFSVFVSELSVRPVSNESAKETKKPLTGSKDPSEDQGSHASEASAASISSTQLVYVVSDLGRLQEWLPDLLETVKQKLEMIGFKNFSSISAALEDSQSALSAHVPALSSRIVQDLSESCFSYLKSALEVPRLYRRTNKEVPSTASSYVDSALKPLYQLQSGHGDKVQPAVMQSWLQEALSDSTHRYFETVSDVLNSVKKMEESLKRLKQARRSPATNPVSSSGGGMSDDDKIRLQLALDVEHLGEQIQRMGLQTSDIKSFPALMELVLAARDQAAAEQP","sequence_length":731,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"732d87e7816801206defb4e79bbdc7d261c1823d26dab9d7d292d9bcd0262df3","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q921L5.json","taxon_id":"10090","uniprot_accession":"Q921L5","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Drosophila melanogaster","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/cog-complex-component-cog2-c-terminal-ipr024603.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024603","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/cog-complex-component-cog2-c-terminal-ipr024603.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/conserved-oligomeric-golgi-complex-subunit-2-n-terminal-ipr024602.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024602","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/conserved-oligomeric-golgi-complex-subunit-2-n-terminal-ipr024602.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/repeat/pfam/cog2-c-pf12022.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12022","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/repeat/pfam/cog2-c-pf12022.yaml"}],"pfam_ids":["PF06148","PF12022"],"protein_name":"Conserved oligomeric Golgi complex subunit 2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MHDPVKKSAHLTAGSTSTAEKLCFDKNEFMKANFSVDEFLHKNRNAPSLEQLRDNLGLYLKGLRAAMIDLINEDYADFVNLSANLVGLDQNIKTIQQPLEQFRSDIESIHGLIDENVTELRAQLEEKRQLREFKRGLQSLKKVYETINKLQDLIDRKLSGEQPIKAVDLERAALDLIQLKFHEKHCFKHLSPDHQGKIQQLEEQLHQHLRRFFNDALSQARNSAPESLERCLRIYITLNACDQAECAFREDVVAPYMTGVIGEQQLQNSPQGLAGIYSKILNFISLHMTDLLRLTLYSDKFPGFNFVVNSYWSDVETRLELHMNSIFAPGNSEVFYVKYKCTRDFLGKIEELLTCSGEQAVTFYRQHKQTKSFEARWNLPVYFQICFQEIAGKFEAQLEPVLQEDSLKDNLTDSDYKISAFNAAKEAMTRCWAEGVYLPEVFPKFYKLNVQVVLRLSRWITDAITQSKGSNFSKPYTRNQLLIALHADIRKLDAHLPELQQLIIKSVPVEQCTKIFSDVLAKSMSCLADTLGAHLTNIQKTLVELLIGECETENVRQVNDLPRLYRKTNREVPTRCSSYVEQMLRPLKAFAQQNESQLGTLVVEQILAEVASHITKAYFNVVSDVLTSVQKTEESLRRLRNVKSGGAATVSTGSSAVMSDDDKIRVQLRVDVTSWRQELCKLNFQATQIDKLVELTNMVEDSIKLKDNSA","sequence_length":710,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"1f27c324d11c250eea54a985654dc42827ad85ce9999e2e67ef734f570baefb4","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q9VF78.json","taxon_id":"7227","uniprot_accession":"Q9VF78","uniprot_release":"2026_03"}],"pfam_id":"PF12022","short_name":"COG2_C","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}