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This protein folds into an alpha/beta structure consisting of a small antiparallel beta-sheet and alpha-helices packed on one side of it.","domain_architectures":14,"interpro_id":"IPR021954","known_evidence_count":null,"matches":705,"name":"Protein CHLORORESPIRATORY REDUCTION 7","partial_evidence_count":null,"pfam_id":"PF12095","proteins":705,"proteomes":578,"short_name":"CRR7","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12095","structures":1,"taxa":1666,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF12095.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":527,"domain_architectures":14,"matches":705,"proteins":705,"proteomes":578,"structures":1,"taxa":1666},"curation_status":"SEEDED","description":"This entry includes protein from blue-green algae and plants, including CRR7 protein from Arabidopsis. CRR7 is part of the chloroplastic NAD(P)H dehydrogenase complex (NDH Complex) involved in respiration, photosystem I (PSI) cyclic electron transport and CO2 uptake [[cite:PUB00075318]]. A member of this family, Ssl3829, was shown to play an important role in the assembly of the NDH-1 hydrophilic arm by accumulating the NAI300 complex and Slr1097 protein in the cytoplasm [[cite:PUB00163390]]. The structure of another member of this family, Asl3597 from Nostoc sp. PCC7120, was determined [[cite:PUB00163389]]. This protein folds into an alpha/beta structure consisting of a small antiparallel beta-sheet and alpha-helices packed on one side of it.","id":"Pfam:PF12095","interpro_id":"InterPro:IPR021954","name":"Protein CHLORORESPIRATORY REDUCTION 7","pfam_id":"PF12095","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"CRR7","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12095"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF12095.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"389aca7f471d25c21909b03bf530791079c49260392bfabf8567a17a5a0f4b7f"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Arabidopsis thaliana","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/crr7-pf12095.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12095","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/crr7-pf12095.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/protein-chlororespiratory-reduction-7-like-superfamily-ipr038150.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038150","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/protein-chlororespiratory-reduction-7-like-superfamily-ipr038150.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/protein-chlororespiratory-reduction-7-3-90-940-40.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:3.90.940.40","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/protein-chlororespiratory-reduction-7-3-90-940-40.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:Q9FL87","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF12095"],"protein_name":"Protein CHLORORESPIRATORY REDUCTION 7, chloroplastic","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"409f0b8a036e186322960ccf1cd5d6d6c015a31a13caa58b38d5ef570a85c90e","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MECSLQKQLFNNGDKLFSSRHNRRVSIEQVHVTDSLSVNSINLFHKPICYPISSIITSRKSKSHFSVCATRRRRVHSNSDTYVLLEAGQDEQFVTEDELKAKLRGWLENWPVNSLPPDLARFDDLDEAVDFLVKAVCELEIDGEVGSVQWYQVRLE","sequence_length":156,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"409f0b8a036e186322960ccf1cd5d6d6c015a31a13caa58b38d5ef570a85c90e","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q9FL87.json","taxon_id":"3702","uniprot_accession":"Q9FL87","uniprot_release":"2026_03"}],"pfam_id":"PF12095","short_name":"CRR7","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}