{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF12206","protein_label":"Uncharacterized protein YqbH","reviewed":true,"short_name":"DUF3599","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf3599-pf12206.yaml","source_record_id":"Pfam:PF12206","source_record_label":"Domain of unknown function (DUF3599)","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"P45924","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF12206","protein_label":"Phage-like element PBSX protein XkdH","reviewed":true,"short_name":"DUF3599","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf3599-pf12206.yaml","source_record_id":"Pfam:PF12206","source_record_label":"Domain of unknown function (DUF3599)","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"P54328","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF12206","protein_label":"","reviewed":null,"short_name":"DUF3599","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf3599-pf12206.yaml","source_record_id":"Pfam:PF12206","source_record_label":"Domain of unknown function (DUF3599)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF12206","protein_label":"Uncharacterized protein YqbH","reviewed":true,"short_name":"DUF3599","source_category":"sequence/homologous_superfamily/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/homologous_superfamily/interpro/xkdh-like-superfamily-ipr038667.yaml","source_record_id":"InterPro:IPR038667","source_record_label":"XkdH-like superfamily","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"P45924","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF12206","protein_label":"Phage-like element PBSX protein XkdH","reviewed":true,"short_name":"DUF3599","source_category":"sequence/homologous_superfamily/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/homologous_superfamily/interpro/xkdh-like-superfamily-ipr038667.yaml","source_record_id":"InterPro:IPR038667","source_record_label":"XkdH-like superfamily","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"P54328","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF12206","protein_label":"Uncharacterized protein YqbH","reviewed":true,"short_name":"DUF3599","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/protein-of-unknown-function-duf3599-2-40-10-370.yaml","source_record_id":"CATH:2.40.10.370","source_record_label":"Protein of unknown function DUF3599","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"P45924","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF12206","protein_label":"Phage-like element PBSX protein XkdH","reviewed":true,"short_name":"DUF3599","source_category":"structure/homologous_superfamily/cath","source_mech":"ProteinTraitsMech","source_path":"data/traits/structure/homologous_superfamily/cath/protein-of-unknown-function-duf3599-2-40-10-370.yaml","source_record_id":"CATH:2.40.10.370","source_record_label":"Protein of unknown function DUF3599","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"P54328","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":32,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":2,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":3},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family of proteins is found in bacteria. Proteins in this family are approximately 120 amino acids in length. This domain is the phage-like element pbsx protein xkdh.","domain_architectures":1,"interpro_id":"IPR024556","known_evidence_count":null,"matches":55,"name":"Domain of unknown function (DUF3599)","partial_evidence_count":null,"pfam_id":"PF12206","proteins":55,"proteomes":49,"short_name":"DUF3599","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12206","structures":1,"taxa":108,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF12206.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":32,"domain_architectures":1,"matches":55,"proteins":55,"proteomes":49,"structures":1,"taxa":108},"curation_status":"SEEDED","description":"This family of proteins is found in bacteria. Proteins in this family are approximately 120 amino acids in length. This domain is the phage-like element pbsx protein xkdh.","id":"Pfam:PF12206","interpro_id":"InterPro:IPR024556","name":"Domain of unknown function (DUF3599)","pfam_id":"PF12206","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF3599","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12206"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF12206.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"b743c141ac02b4c2f35bc20256a506a99da72e33129fb2d6817f8b5476045e5a"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacillus subtilis (strain 168)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf3599-pf12206.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12206","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf3599-pf12206.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/xkdh-like-superfamily-ipr038667.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038667","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/xkdh-like-superfamily-ipr038667.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/protein-of-unknown-function-duf3599-2-40-10-370.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:2.40.10.370","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/protein-of-unknown-function-duf3599-2-40-10-370.yaml"}],"pfam_ids":["PF12206"],"protein_name":"Uncharacterized protein YqbH","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSYQSLLTHRCDIYHLQEKKENRKQKFGVPVEDVQPVFSYPDEPDIENQPCYFTEKSQSIIQQESNVSIYQSFLVHFPATADIRVNDRAVWDGTAYKLQKPRKIRNHHWEVTAVREVEYL","sequence_length":120,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"04f6cecaff556bc9f9f73c36c12a42b3fd632202b9aced73cac75e53d7ffd200","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P45924.json","taxon_id":"224308","uniprot_accession":"P45924","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacillus subtilis (strain 168)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf3599-pf12206.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12206","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf3599-pf12206.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/homologous_superfamily/interpro/xkdh-like-superfamily-ipr038667.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR038667","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/homologous_superfamily/interpro/xkdh-like-superfamily-ipr038667.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/structure/homologous_superfamily/cath/protein-of-unknown-function-duf3599-2-40-10-370.yaml","qualification_status":"NOT_ASSESSED","record_id":"CATH:2.40.10.370","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/structure/homologous_superfamily/cath/protein-of-unknown-function-duf3599-2-40-10-370.yaml"}],"pfam_ids":["PF12206"],"protein_name":"Phage-like element PBSX protein XkdH","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSYRQMLIHRCDIYHEAAQAPSAGRFGIPADRLQPVISYPDTPDEQDVPCYFTEKTQQLIQEEPDQTVYHSFLVHFPLSADIRVNDKIIWENHKYILKLPKRIRHHHWEVVAVRDESL","sequence_length":118,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"1ac0d85d207b51114cf5e4205e28aa8de5ec78d8400a292c666010b2b180a31d","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P54328.json","taxon_id":"224308","uniprot_accession":"P54328","uniprot_release":"2026_03"}],"pfam_id":"PF12206","short_name":"DUF3599","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}