{"cross_mech":[],"family":{"alphafold_models":2841,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family represents the haspin-like kinase domains.","domain_architectures":94,"interpro_id":"","known_evidence_count":null,"matches":3607,"name":"Haspin like kinase domain","partial_evidence_count":null,"pfam_id":"PF12330","proteins":3556,"proteomes":2660,"short_name":"Haspin_kinase","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12330","structures":41,"taxa":7040,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF12330.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":2841,"domain_architectures":94,"matches":3607,"proteins":3556,"proteomes":2660,"structures":41,"taxa":7040},"curation_status":"SEEDED","description":"This family represents the haspin-like kinase domains.","id":"Pfam:PF12330","name":"Haspin like kinase domain","pfam_id":"PF12330","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Haspin_kinase","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12330"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF12330.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"8982c79851e9246a0ecca79999a8d9fa19c2b48750c93fdf47f610f9b8a485a0"}},"protein_examples":{"candidate_count":6,"discovery_scanned":true,"example_count":6,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Arabidopsis thaliana","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/histone-h3t11-kinase-activity-go0035402.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0035402","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/histone-h3t11-kinase-activity-go0035402.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0072354","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024604","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml"}],"pfam_ids":["PF12330"],"protein_name":"Serine/threonine-protein kinase haspin homolog","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGQRVDLWSEVIKSEEEDGDIPKIEAVFQRRKKPDKSSEAVNFGWLVKGARTSSVNGPKRDSWARSLSTRGRESIAVRAYVNNQPQKKAAGRKKPPIPKGKVVKAPDFQKEKEYFRDIDAFELLEESPSPNKSSTWTMGEQVVPEMPHLSTRLEKWLISKKLNHTCGPSSTLSKILENSAIHQESVCDNDAFDSLSLKTPDKSSAGNTSVFRLIPSCDENLAAEDVPVRKIKMESIDLEDELKRLSLTSDLIPTHQDFDQPILDLLSACGQMRPSNFIEAFSKFCEPESIVKIGEGTYGEAFRAGSSVCKIVPIDGDFRVNGEVQKRADELLEEVILSWTLNQLRECETTAQNLCPTYIKTQDIKLCQGPYDPILIKAWEEWDAKHGSENDHPDFPEKQCYVMFVLEHGGKDLESFVLLNFDEARSLLVQATAGLAVAEAAFEFEHRDLHWGNILLSRNNSDTLPFILEGKQVCIKTFGVQISIIDFTLSRINTGEKILFLDLTSDPYLFKGPKGDKQSETYRKMKAVTEDYWEGSFARTNVLWLIYLVDILLTKKSFERSSKHERELRSLKKRMEKYESAKEAVSDPFFSDMLMDQIS","sequence_length":599,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"318b68244f6756d4f33566e5dee0299e9c170e06ec1662cc8c9d87969ac879c3","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/O80528.json","taxon_id":"3702","uniprot_accession":"O80528","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0072354","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/mitotic-morphogenesis-checkpoint-signaling-go0044879.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0044879","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/mitotic-morphogenesis-checkpoint-signaling-go0044879.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024604","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/haspin-kinase-pf12330.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12330","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/haspin-kinase-pf12330.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P32789","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF12330"],"protein_name":"Serine/threonine-protein kinase Haspin homolog ALK2","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"a863df4f0486d2ff26e228afa2030b7ca943fe5b691ac5a3d13f79dbc16eecf5","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MNFDAVADQQMTDRRYFALEVAESDDADSSLNSSSMGSPAVDVGRKVYKITSHKGSAEDESQSFFTSSDSPTSKTRPVGKTIENDDYYGKRSSTGSSLKQLFNKININDTAHSSNKENVSQSVLSENKLLSPSKRLSKQGLTKVTNSKFRTPLRPISNQSTLSRDEPVKDFRSLKFRSGSDFKCWGDEKTSSHVHSSSVNSVNSFTSTTSSSKWKFWKNDNLLSRSLSSRSVNDQDPNFVQPKPTNSLQKKSSISSFHNSIFGGGKHTEKKRNSGFIMPDHQSTKELNHKHSSSNLSFRSLKHKTSHSSLNKLKVRRKGNTQELNHPIKKTCQISLPVPDQVSKDKIQLKLKNSTSLASLSSEVTPINTLDYNDSILQQILQLCDVKYILHDLREAQSLGLFTLNTRSVQLSHNFWQTYHSDMQTSLICKKVCLGALSDLTTSNLISLHELKSLRLIQGTSGVANLLQAYVVPSNQCENDQNLILYLFFKYQGTPLSRCSNIDYSQALSIFWQCSSILYVAESKFQLEHRNLTLDHILIDSKGNVTLIDMKCCRFLNIDNNKASYTRLDHHYFFQGRGTLQFEIYELMRSMLPQPISWATFEPRTNLLWLYHLSSSLLKMAKKAVVSGALNREENILIELTHLLDPARKHSKTIFKKELVIRTCGDLLSLKGEIMQ","sequence_length":676,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"a863df4f0486d2ff26e228afa2030b7ca943fe5b691ac5a3d13f79dbc16eecf5","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P32789.json","taxon_id":"559292","uniprot_accession":"P32789","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0072354","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/mitotic-morphogenesis-checkpoint-signaling-go0044879.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0044879","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/mitotic-morphogenesis-checkpoint-signaling-go0044879.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024604","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/haspin-kinase-pf12330.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12330","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/haspin-kinase-pf12330.yaml"}],"pfam_ids":["PF12330"],"protein_name":"Serine/threonine-protein kinase Haspin homolog ALK1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MLLHFDIVIQLLSSHTLKSHQVEPPMDFETSFEEFVEDKRFIALEVSDNDDDCDTDLTADTADELESSAILKMRESDASLNVTTGNNTSRKTTSNSKKRWSLLSNHSAVSSSKSKKRWSVLSSSFTSESHKDRESRNVLQQKRKSLQSYSSLDTVASNSSISASSSLKRSSTGLSLRQLFTKIGINDDISQPGIGIPQGKENLPPTMGKKNSSIASTSSENRLRTPLKPLVNHSKRPTSQPQQQQPLYNASLSSRRSSISSTVSSSSSSKWRFWKRNKNQTPALLQPDHHSLKTFPAVNRRDSMTPVEPRNMVKHKTSFSDFHKTIFSSNTYSESSDTISSMEITLKNKASSSSLSLNVLKKRNSQSSLKHKSSHASLQKFKRNKGKSSMIAPSTATNSSNDDSCSYSSKNSTLSHRISLPVPDQVSRDKIQNKLRYSTSLLSLNSKSSLPMNKNDHDETLLRQILLNCDIKRILNPAKGDVLPLINDVNHLSSIQLTSNVWQIGEVICKKVSLGTIDDITWDRKFLSLQELEKLKIMQQKFDGIPQLLKSFVVKEANGGLYLYLLFKDHGTPISLISLKNWKQILKIFWSCAGIIHGLEKNLKFEHRNLTLDNILIDGNGNITIIDFKCSRLQTPQDDVLYLRLDHPLFFLNGKDKSKINEYQYQFEFEIYQSMRILLNMDASAFEPMTNLYWLYYLSRVLLKFGDRKLGKNDANRDKMARVINHLEMNLAVHKRGGQLFKRLETEDIKNTGDLLKLYK","sequence_length":760,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"5a06135590cc876730d69ee31d7750f5be374c080b2eb57b5faa34ccfd407c35","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/P43633.json","taxon_id":"559292","uniprot_accession":"P43633","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Drosophila melanogaster","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0072354","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/positive-regulation-of-maintenance-of-mitotic-sister-chromatid-cohesion-centrome-go2000720.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:2000720","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/positive-regulation-of-maintenance-of-mitotic-sister-chromatid-cohesion-centrome-go2000720.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/positive-regulation-of-maintenance-of-sister-chromatid-cohesion-go0034093.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0034093","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/positive-regulation-of-maintenance-of-sister-chromatid-cohesion-go0034093.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/pathway/go/positive-regulation-of-protein-localization-to-chromatin-go0120187.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0120187","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/pathway/go/positive-regulation-of-protein-localization-to-chromatin-go0120187.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024604","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml"}],"pfam_ids":["PF12330"],"protein_name":"Serine/threonine-protein kinase haspin homolog","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MLSISKTKMDFLEEGRWKDPFDELLDSRTKLSKMNIVKQNVRVTYNIDSSVENSSYIEIKEPNHKNEPLTLEDCSIKVYCPSDSISTPCDKRLGGTTGLFETDLSPITRLKLEGVEDSRDKCADTNEADLYVNVEILFQNINSSPKKCSNFGKKRLSNLNKMVTAVHPSISLNPGKWRKSLNNFIRSKITETNFTKKVERRSSICQDRKSLVLKGEHKFENKYEEDVLKYCHQCTPLPFNTAYEQHKLLNTKKIGEGAYGEVFRCSRNQEVLKDHISDIVLKIIPLEGSTVINGEKQKTFSQILPEIIITKKMCSLRTSKTNSTNGFVSIQKVSLVKGRYPPHFIKLWEKYDNEKGSENDHPELFGDNQLFAVLELKFAGSDMANFKFLNSEQSYYALQQIILALAVGEEEYQFEHRDLHLGNILIEYTNKKHIVCTFKSSNLTLLSKGVNVTIIDYTLSRVTINDCCYFNDLSRDEELFQATGDYQYDVYRMMRNELKNNWSSFSPKTNIIWLSYVIVKVLDSVKYKSINTKVHRMYIDKIKELKNIIMTFESASHCANYLFNLN","sequence_length":566,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"bdbaace3cfefbe3980eabcfafebe361479b712cb40643cf3e085d0c9d9a664ce","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P83103.json","taxon_id":"7227","uniprot_accession":"P83103","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0072354","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024604","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/haspin-kinase-pf12330.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12330","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/haspin-kinase-pf12330.yaml"}],"pfam_ids":["PF12330"],"protein_name":"Serine/threonine-protein kinase haspin","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MAASLPGPGSRLFRTYGAADGRRQRRPGREAAQWFPPQDRRRFFNSSGSSDASIGDPSQSDDPDDPDDPDFPGSPVRRRRRRPGGRVPKDRPSLTVTPKRWKLRARPSLTVTPRRLGLRARPPQKCSTPCGPLRLPPFPSRDSGRLSPDLSVCGQPRDGDELGISASLFSSLASPCPGSPTPRDSVISIGTSACLVAASAVPSGLHLPEVSLDRASLPCSQEEATGGAKDTRMVHQTRASLRSVLFGLMNSGTPEDSEFRADGKNMRESCCKRKLVVGNGPEGPGLSSTGKRRATGQDSCQERGLQEAVRREHQEASVPKGRIVPRGIDRLERTRSSRKSKHQEATETSLLHSHRFKKGQKLGKDSFPTQDLTPLQNVCFWTKTRASFSFHKKKIVTDVSEVCSIYTTATSLSGSLLSECSNRPVMNRTSGAPSSWHSSSMYLLSPLNTLSISNKKASDAEKVYGECSQKGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK","sequence_length":798,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"156a54656cbd089f3fa5dc90c7d33f1a96e549d5a7065e429a557db3a64d9e56","sequence_version":3,"source_url":"https://rest.uniprot.org/uniprotkb/Q8TF76.json","taxon_id":"9606","uniprot_accession":"Q8TF76","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml","qualification_status":"NOT_ASSESSED","record_id":"GO:0072354","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/molecular_function/go/histone-h3t3-kinase-activity-go0072354.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR024604","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/serine-threonine-protein-kinase-haspin-c-terminal-ipr024604.yaml"}],"pfam_ids":["PF12330"],"protein_name":"Serine/threonine-protein kinase haspin","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MAQAHPRSGTRLFRTYAARGVRGSQRQPGGLAEQWFQPPNLKRAFSSSLSDSNESPAVASDDPDDPDFPGSLVGQRRRRPRGSGSRNQRTLTNTPRVQRLRPRPPQKCSTPCSRLRPPPFPNCSPGCLGSDHSVCIQSRDSNELGTSASLFSSPASPGAPDPLYADSAVPGSFHLPAASLSEPSVPCPQVAATGDRYTGRALRAEASFRSSLFSLVNSGATEENKFGTDGENVKESCCERRQQMGNRLTDPDLTSPGKRKAACKKVVSQGVDQRDYEESSACKDLRVPGEISRPKRTGPLRKRKQQEATGTPPRHYHQSKKKRKASVSLWNLNTSQRDSWTKTRASFGFHKKKIITSVIEVCSSVASSSSRSLLSECSTPPIKNRAHLTVSSRCSSVYLLSPLKTLHVTDQRPSYAEKVYGECNQEGPIPFSDCLSTEKLERCEKIGEGVFGEVFQIINDQAPVALKIIAIEGLDLVNGSHQKTFEEILPEIIISKELSLLSSEAYNRTEGFIGLNSVHCVQGLYPPLLLKAWDHYNTTKRSANDRPDFFQEDQLFIILEFEFGGVDLERMKTKLSSVATAKSILHQITASLAVAEASLHFEHRDLHWGNVLLKKTNLKELRYTLNGKTSTIPTHGLQVNIIDYTLSRLERDGIVVFCDISAEEDLFTGEGDYQFEIYRLMRKENKNCWGEYHPYNNVLWLHYLTDKILNKMKFKTKCQSAAMKQIRKNLQHFHRTVLSFSSATDLLCQHSLFR","sequence_length":754,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"c7f743908c94bff5749dbf26a6c207331e356ed679bed50407a216562a85dd2a","sequence_version":3,"source_url":"https://rest.uniprot.org/uniprotkb/Q9Z0R0.json","taxon_id":"10090","uniprot_accession":"Q9Z0R0","uniprot_release":"2026_03"}],"pfam_id":"PF12330","short_name":"Haspin_kinase","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}