{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF12396","protein_label":"","reviewed":null,"short_name":"DUF3659","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/vdag-07280-repeated-domain-ipr022124.yaml","source_record_id":"InterPro:IPR022124","source_record_label":"VDAG_07280, repeated domain","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF12396","protein_label":"Virulence-associated protein VDAG_07280","reviewed":true,"short_name":"DUF3659","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf6987-pf22485.yaml","source_record_id":"Pfam:PF22485","source_record_label":"Domain of unknown function (DUF6987)","source_section":"canonical_examples","taxon_id":"NCBITaxon:498257","taxon_label":"Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)","uniprot_accession":"G2XBE2","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF12396","protein_label":"Virulence-associated protein VDAG_07280","reviewed":true,"short_name":"DUF3659","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf3659-pf12396.yaml","source_record_id":"Pfam:PF12396","source_record_label":"Protein of unknown function (DUF3659)","source_section":"canonical_examples","taxon_id":"NCBITaxon:498257","taxon_label":"Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)","uniprot_accession":"G2XBE2","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF12396","protein_label":"","reviewed":null,"short_name":"DUF3659","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf3659-pf12396.yaml","source_record_id":"Pfam:PF12396","source_record_label":"Protein of unknown function (DUF3659)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":784,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":1,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":2},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain family is found in bacteria and eukaryotes, and is approximately 70 amino acids in length.","domain_architectures":75,"interpro_id":"IPR022124","known_evidence_count":null,"matches":9374,"name":"Protein of unknown function (DUF3659)","partial_evidence_count":null,"pfam_id":"PF12396","proteins":1378,"proteomes":824,"short_name":"DUF3659","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12396","structures":0,"taxa":1647,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF12396.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":784,"domain_architectures":75,"matches":9374,"proteins":1378,"proteomes":824,"structures":0,"taxa":1647},"curation_status":"SEEDED","description":"This domain family is found in bacteria and eukaryotes, and is approximately 70 amino acids in length.","id":"Pfam:PF12396","interpro_id":"InterPro:IPR022124","name":"Protein of unknown function (DUF3659)","pfam_id":"PF12396","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF3659","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12396"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF12396.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"514cdec41fa2516968c4534233f32db39e12005051c076eb65f397ff18f5e832"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf6987-pf22485.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF22485","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf6987-pf22485.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf3659-pf12396.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12396","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf3659-pf12396.yaml"}],"pfam_ids":["PF12396","PF22485"],"protein_name":"Virulence-associated protein VDAG_07280","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MADTTTKKAEDTKQSVGNVVTATGDIVGKDGGIVGKALPLDNASAGGSKKGIFGTLMGATKGVKGVVDTVDGTVQTVEKGLPLVGDLTKGLGLGNGGGGFGGLLGKKQEDRSAEDKAATTEQAKKELFDNSDKAADAAPIDLKDQEAVDNAKTEVETKSQPPQSEASESKDEATEATTEASTDDNETVKQSGKDLTDTVSGAVGGAKDAVESTASGAKDTVEDTTQKTTDTAEDTTTKATDAVEDTTSKATDAAEDTTSKATDAAEDTTSKAADAAEKTADDVQDTAEETAETAQSTVDDTSKDVPKDTDSAKGLDDTADDAFDTAEQTTSDAKDSADKTASDDKVEDTKAAAEGAKDTAEETAEDAKDAASEAPKGLSEQAQSQLDEMETVADVQVENPFQKFEGAQLDDEGKVIFDNQSIGKVVEGDPLELANKEIAPDGAILNDEGSEIGRVELKSEIAEDLQKQAEALAGLKDAKVNKAGNLVKNDAVIGRIVEGTIKNLIGRKADAQGRIWNDSGEQIGRAEPLADKEREEFKEPSPFEDFPDAVVQSNGDVTFEGEKIGVLVEGDPKKLKGKHIDEDGEVQDRQGNVIGRAERWEPEEEEPAPEVDNSLLAEKRVNKAGLVVDSNGTAFGRVVEGDVAKLINRMCNKKGEVLSESGEVIGRAELIPEHERHEKKDQPFENFPDAVVQANGDVTHNGEIVGRLIEGDAKKLQNSKVDADGDVVRDGNVIGKAERYTPEEPEPEPEQDKSILGGKRVNKAGFVVDSNGVPYGRVVEGDISRLVNRMCDKQGNVLSESGDKLGVAEVLPEGERELKKEGPFAELPGCTVAKDGTVVTPSGDIVGRLIEGDGKKLFGREVDDDGEILHQGNVIGRAERWEPEPEPEKEKGPFAGLKVNKQGDVYRDGELVARLTSGELSVCSGAEIDDDNDVINHKGTSVGHVTAIADIPEPEPEEPKESEEEKKAREEAEQDEKLAKNLASQVEQSLDKIRPICKMITDKIEKAERTPKDELDEEALVKEVKPLIEEGGNILSELNGTIRAMDPDGRIQRNAKHKSSTSEASPAEHHLADLLKELSGSVVTCVENAKKKIADMPHAKKHLNPLWALLTEPLGQILAAVGLLLAGVLNLVGRLLSGLGLGGIIDGLLGTLGLNRVLEGLGLSSITGALTGKNK","sequence_length":1175,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"a73a9f70fd8106e92b42665bd793973559b73bda9595a9b20685f3657807c6b6","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/G2XBE2.json","taxon_id":"498257","uniprot_accession":"G2XBE2","uniprot_release":"2026_03"}],"pfam_id":"PF12396","short_name":"DUF3659","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}