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It is found in association with [pfam:PF04196].","domain_architectures":6,"interpro_id":"IPR022531","known_evidence_count":null,"matches":432,"name":"RNA-directed RNA polymerase L, PA-C-like domain","partial_evidence_count":null,"pfam_id":"PF12603","proteins":432,"proteomes":131,"short_name":"L_PA-C-like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12603","structures":13,"taxa":363,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF12603.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":123,"domain_architectures":6,"matches":432,"proteins":432,"proteomes":131,"structures":13,"taxa":363},"curation_status":"SEEDED","description":"This domain is found in RNA-directed RNA polymerase L from from Bunyavirales. It has been described as the PA-C-like domain which forms a narrow and positively charged cleft with the thumb domain, where the 3' RNA is likely bound [[cite:PUB00101134]]. It is found in association with [pfam:PF04196].","id":"Pfam:PF12603","interpro_id":"InterPro:IPR022531","name":"RNA-directed RNA polymerase L, PA-C-like domain","pfam_id":"PF12603","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"L_PA-C-like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12603"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF12603.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"dc29a98200af6b0ce576ae7ee3e0e81622e94418ed393a6b58b0dcb8f6c722f9"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Dabie 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