{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF12870","protein_label":"","reviewed":null,"short_name":"DUF4878","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf4878-ipr024267.yaml","source_record_id":"InterPro:IPR024267","source_record_label":"Domain of unknown function DUF4878","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF12870","protein_label":"Uncharacterized protein aq_142","reviewed":true,"short_name":"DUF4878","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf4878-pf12870.yaml","source_record_id":"Pfam:PF12870","source_record_label":"Domain of unknown function (DUF4878)","source_section":"canonical_examples","taxon_id":"NCBITaxon:224324","taxon_label":"Aquifex aeolicus (strain VF5)","uniprot_accession":"O66537","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF12870","protein_label":"","reviewed":null,"short_name":"DUF4878","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf4878-pf12870.yaml","source_record_id":"Pfam:PF12870","source_record_label":"Domain of unknown function (DUF4878)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":219,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":1,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This is a family of putative lipoproteins from bacteria. The family is probably related to the NTF2-like transpeptidase family.","domain_architectures":3,"interpro_id":"IPR024267","known_evidence_count":null,"matches":311,"name":"Domain of unknown function (DUF4878)","partial_evidence_count":null,"pfam_id":"PF12870","proteins":311,"proteomes":294,"short_name":"DUF4878","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12870","structures":1,"taxa":622,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF12870.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":219,"domain_architectures":3,"matches":311,"proteins":311,"proteomes":294,"structures":1,"taxa":622},"curation_status":"SEEDED","description":"This is a family of putative lipoproteins from bacteria. The family is probably related to the NTF2-like transpeptidase family.","id":"Pfam:PF12870","interpro_id":"InterPro:IPR024267","name":"Domain of unknown function (DUF4878)","pfam_id":"PF12870","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF4878","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12870"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF12870.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"d6cec90d372de5a500ee3548a6d8c77c2ee949d9493304b253b9a01012f4344d"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Aquifex aeolicus (strain VF5)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf4878-pf12870.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF12870","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf4878-pf12870.yaml"}],"pfam_ids":["PF12870"],"protein_name":"Uncharacterized protein aq_142","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MRNKVLIVLAVIAGALILKSCGEPYSGAKETVGEFMEEIAEGEGRDAIKYLYPAYRDELAKNFKLPVQFTEMKPSEVLACVLSTMGRNIDEVEIKKAIAVNPNTANVVVKVEDKEGIEKFFSFTVVKEGDKWYIAKIEKYIPQVGR","sequence_length":146,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"5c4c8e810ebaaed4e6f66cdb6a971d5df20826c42f51fc292a2318debe332ea3","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/O66537.json","taxon_id":"224324","uniprot_accession":"O66537","uniprot_release":"2026_03"}],"pfam_id":"PF12870","short_name":"DUF4878","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}