{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF12990","protein_label":"","reviewed":null,"short_name":"DUF3874","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf3874-ipr024450.yaml","source_record_id":"InterPro:IPR024450","source_record_label":"Domain of unknown function DUF3874","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF12990","protein_label":"","reviewed":null,"short_name":"DUF3874","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf3874-pf12990.yaml","source_record_id":"Pfam:PF12990","source_record_label":"Domain of unknonw function from B. Theta Gene description (DUF3874)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"KNOWN_HISTORICAL_DUF"}],"family":{"alphafold_models":208,"candidate_reasons":["short_name_matches_duf"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":true,"records_by_mech":{},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"Based on Bacteroides thetaiotaomicron gene BT_4228, a putative uncharacterized protein As seen in gene expression experiments (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2231), It appears to be upregulated in the presence of host or other bacterial species vs when in culture [[cite:PUB00056011],[cite:PUB00056012]].","domain_architectures":3,"interpro_id":"IPR024450","known_evidence_count":null,"matches":294,"name":"Domain of unknonw function from B. Theta Gene description (DUF3874)","partial_evidence_count":null,"pfam_id":"PF12990","proteins":294,"proteomes":80,"short_name":"DUF3874","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12990","structures":0,"taxa":128,"unknown_status":"KNOWN_HISTORICAL_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF12990.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":208,"domain_architectures":3,"matches":294,"proteins":294,"proteomes":80,"structures":0,"taxa":128},"curation_status":"SEEDED","description":"Based on Bacteroides thetaiotaomicron gene BT_4228, a putative uncharacterized protein As seen in gene expression experiments (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2231), It appears to be upregulated in the presence of host or other bacterial species vs when in culture [[cite:PUB00056011],[cite:PUB00056012]].","id":"Pfam:PF12990","interpro_id":"InterPro:IPR024450","name":"Domain of unknonw function from B. Theta Gene description (DUF3874)","pfam_id":"PF12990","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"KNOWN_HISTORICAL_DUF","short_name":"DUF3874","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12990"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF12990.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"67c1cb66c592271f56e67d1d3b4c305bb0306182622787ecd4bb03dc30518e4d"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF12990","short_name":"DUF3874","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}
