{"cross_mech":[],"family":{"alphafold_models":329,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"RNaseH domain of the pPIWI_RE PIWI/Argonaute module. pPIWI_RE is found in a conserved three-gene island that also contains a DinG-type helicase and an REase nuclease. This three gene island is predicted to form a conflict system which targets R-loop formation of invasive plasmids during plasmid replication [[cite:PUB00091016]].","domain_architectures":11,"interpro_id":"IPR024996","known_evidence_count":null,"matches":695,"name":"RNaseH domain of pPIWI_RE","partial_evidence_count":null,"pfam_id":"PF13032","proteins":693,"proteomes":603,"short_name":"RNaseH_pPIWI_RE","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13032","structures":0,"taxa":1031,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF13032.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":329,"domain_architectures":11,"matches":695,"proteins":693,"proteomes":603,"structures":0,"taxa":1031},"curation_status":"SEEDED","description":"RNaseH domain of the pPIWI_RE PIWI/Argonaute module. pPIWI_RE is found in a conserved three-gene island that also contains a DinG-type helicase and an REase nuclease. This three gene island is predicted to form a conflict system which targets R-loop formation of invasive plasmids during plasmid replication [[cite:PUB00091016]].","id":"Pfam:PF13032","interpro_id":"InterPro:IPR024996","name":"RNaseH domain of pPIWI_RE","pfam_id":"PF13032","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"RNaseH_pPIWI_RE","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13032"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF13032.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"8b2508d3035a91119c83dbdd0a32440e1d057d1a996a87e71c6341242e6eb398"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF13032","short_name":"RNaseH_pPIWI_RE","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}