{"cross_mech":[],"family":{"alphafold_models":2926,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain, previously known as DUF4105, is found N-terminal in Lipoprotein N-acyltransferase Lnb from Bacteroides and related uncharacterised bacterial proteins. Lnb functions as a lipoprotein N-acyltransferase in its native cell background [[cite:PUB00158892]]. It is composed of two domains, N-terminal (this entry) and C-terminal alpha- helical transmembrane domain. The domain represented by this entry contains a highly conserved histidine residue and a well-conserved NCT motif. Its predicted structure has a significant similarity to the papain-like cysteine peptidases. In addition, the putative catalytic triad Asn-His-Cys is highly conserved. This domain is also found in combination with other domains.","domain_architectures":15,"interpro_id":"IPR025178","known_evidence_count":null,"matches":4839,"name":"Lnb N-terminal periplasmic domain","partial_evidence_count":null,"pfam_id":"PF13387","proteins":4837,"proteomes":3704,"short_name":"Lnb_N","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13387","structures":0,"taxa":5476,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF13387.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":2926,"domain_architectures":15,"matches":4839,"proteins":4837,"proteomes":3704,"structures":0,"taxa":5476},"curation_status":"SEEDED","description":"This domain, previously known as DUF4105, is found N-terminal in Lipoprotein N-acyltransferase Lnb from Bacteroides and related uncharacterised bacterial proteins. Lnb functions as a lipoprotein N-acyltransferase in its native cell background [[cite:PUB00158892]]. It is composed of two domains, N-terminal (this entry) and C-terminal alpha- helical transmembrane domain. The domain represented by this entry contains a highly conserved histidine residue and a well-conserved NCT motif. Its predicted structure has a significant similarity to the papain-like cysteine peptidases. In addition, the putative catalytic triad Asn-His-Cys is highly conserved. This domain is also found in combination with other domains.","id":"Pfam:PF13387","interpro_id":"InterPro:IPR025178","name":"Lnb N-terminal periplasmic domain","pfam_id":"PF13387","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Lnb_N","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13387"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF13387.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"560b0183997ad7a771dca3980310e2cec8bd62c6f8a9fb4ff27850608a226001"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF13387","short_name":"Lnb_N","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}